Philippe Garot
Latest contributions
Editorial - The Essentials of left atrial appendage closure
06 Jul 2026
Philippe Garot introduces this special report, which brings together leading experts to review the latest evidence, practical considerations and future directions in LAAC.

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Combined mitral repair and LAA closure with two separate septal punctures - LIVE case
Recommended by PCR
21 May 2026 – From EuroPCR 2026
A 79‑year‑old man with hypertension, a history of basal cell carcinoma and psoriasis, presented with symptomatic severe primary MR (flail P2 due to ruptured chordae) and bleeding complications (recurrent skin bleeding) while on DOAC therapy for permanent atrial fibrillation.
Two G5 MitraClip devices were implanted. Subsequently, through...
Outcomes of LAA closure vs. DOAC in patients with atrial fibrillation across different age groups
21 May 2026 – From EuroPCR 2026
This major late-breaking trial from EuroPCR 2026 highlights new insights from the CHAMPION AF study, one of the largest randomised trials comparing left atrial appendage closure (LAAC) with direct oral anticoagulants (DOACs) in patients with atrial fibrillation. In this interview, Philippe Garot and Jens Erik Nielsen-Kudsk...
Major Late-Breaking Trials from EuroPCR 2026
20 May 2026 – From EuroPCR 2026
This session presents major late-breaking trials from EuroPCR 2026, reviewing contemporary evidence on coronary revascularization in TAVI patients, long-term outcomes of PCI versus CABG for left main disease, and comparative effectiveness of LAA closure versus NOAC in atrial fibrillation across age groups, with clinical practice implications.
Insight from recent evidence in structural heart disease: indications for LAA closure (CHAMPION) and PCI in TAVI candidates (PRO-TAVI)
20 May 2026 – From EuroPCR 2026
This session reviews recent evidence impacting the management of structural heart disease, focusing on left atrial appendage (LAA) closure indications and PCI considerations in transcatheter aortic valve implantation (TAVI) candidates. It discusses optimal strategies for coronary artery disease in TAVI patients and evaluates findings from the...
Align for the future with structural heart innovations - LIVE case and major trial updates
19 May 2026 – From EuroPCR 2026
Stay abreast of structural heart innovations with expert discussions on best-in-class transcatheter aortic valve implantation (TAVI) practices, including imaging, sizing, and procedural strategies. This session with LIVE case introduces the novel Myval Octapro+ transcatheter heart valve (THV), its design philosophy, and potential clinical benefits, along with...
How to prevent and manage complex and complicated LAA closure cases?
19 May 2026 – From EuroPCR 2026
Designed to enhance procedural success in transcatheter left atrial appendage closure, this session addresses identification of complex anatomies, management of intraprocedural challenges, and strategies to prevent and handle complications, illustrated by practical case examples and expert evaluations.
Building evidences to address current challenges in the treatment of aortic stenosis
21 May 2026 – From EuroPCR 2026
At EuroPCR 2026, Andreas Baumbach, Philippe Garot and Rutger-Jan Nuis discuss three important trials that could help shape the future management of aortic stenosis.
The BASELINE trial compares self-expanding and balloon-expandable valves in patients undergoing valve-in-valve TAVI for a failing surgical bioprosthesis. The START YOUNG trial focuses...
What CHAMPION-AF means for the future of left atrial appendage closure
16 Jun 2026
In this discussion, Philippe Garot and Saibal Kar review the implications of the CHAMPION-AF trial for the future of left atrial appendage closure (LAAC). The study demonstrated that LAAC is non-inferior to NOACs for preventing stroke, systemic embolism and death, while significantly reducing long-term bleeding.
These findings...
Is LAA Closure ready for prime time?
04 May 2026
An educational series led by Philippe Garot which explores the latest evidence on LAAC for stroke prevention in atrial fibrillation, including CHAMPION-AF, patient selection, procedural techniques and future directions.
Digital late breakers: will LAAC become standard practice for patients with AF?
15 Apr 2026
In this replay, P. Garot, M. Bergmann and J.E. Nielsen‑Kudsk review current indications for LAAC, insights from the CHAMPION‑AF trial and practical case learnings.
All about PCR’s Teaching Assessment Board (TAB)
03 Dec 2025
Learn how session feedback is compiled to create a virtuous cycle of continuous refinement for education in #interventionalcardiology
Mitral TEER and LAA closure - LIVE Case
17 Nov 2025 – From PCR London Valves 2025
Watch a LIVE case followed by a recorded case regarding a 91-year-old female with permanent AF, LAD PCI three months earlier, and recurrent GID bleeding who presented with symptomatic severe primary mitral regurgitation due to P2 prolapse and flail. CT imaging showed a LAA with a...
Mitral paravalvular leak closure: procedural planning and step-by-step performance
17 Nov 2025 – From PCR London Valves 2025
This session provides an expert overview of mitral paravalvular leak closure, emphasizing critical clinical and anatomical selection criteria. It covers essential pre-procedural imaging and planning strategies, complemented by an educational recorded case and a review of immediate and long-term procedural outcomes.
LAA closure is evolving: are you ready?
17 Nov 2025 – From PCR London Valves 2025
This session addresses the evolving landscape of left atrial appendage (LAA) closure in stroke prevention for atrial fibrillation patients. It reviews unmet clinical needs, evaluates the latest evidence and guideline recommendations, and identifies patient populations that benefit most from LAA closure, with discussions on balancing efficacy...
Mastering simple and complex LAA closure: a step-by-step case-based approach
16 Nov 2025 – From PCR London Valves 2025
This case-based session offers a comprehensive approach to mastering left atrial appendage (LAA) closure, emphasizing the critical role of imaging from pre-procedural planning through execution. It covers patient selection, procedural strategies from experienced operators, device selection tailored to anatomy, and nuanced decision-making during challenging device releases...
Sealing the risk: a case of left atrial appendage closure
15 Sep 2025
A 76-year-old woman with permanent atrial fibrillation, a history of breast cancer, and a recent diagnosis of an intestinal stromal tumour presents with a high thromboembolic and bleeding risk, making long-term anticoagulation unsafe. Cardiac CT reveals a challenging left atrial appendage anatomy. How would you treat this...

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LAAC: current and future indications
03 Jun 2025
Watch the replay of this webinar and learn about the evidence (current guidelines and indications) for LAAC in 2025, and so much more!
TAVI for bioprosthetic valve failure - LIVE Case
22 May 2025 – From EuroPCR 2025
A 68-year-old male patient with a history of Sapien 3 26 mm TAVI (2021), complicated by the need for two valves (one displaced in the descending aorta) and permanent pacemaker implantation, as well as endocarditis (2022), presented with symptomatic bioprosthesis failure and reduced LV function (20...
Combined LAA closure and transcatheter mitral valve repair - LIVE Case
22 May 2025 – From EuroPCR 2025
An 82-year-old male patient with a history of PM (pacemaker) implantation in 2024, and ischaemic cardiomyopathy presented with symptomatic heart failure due to severe secondary mitral regurgitation and impaired LV function (EF 40 %). He also presented with recurrent gastro-intestinal bleeding while on DOAC for atrial...
Academic Research Consortium initiative on left atrial appendage closure – standardising definitions and endpoints to move forward
21 May 2025
Philippe Garot describes the EuroPCR 2025 session on left atrial appendage closure (LAAC), which offers a preview of the upcoming new consensus document developed by the Academic Research Consortium.

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Case-based learning on different aspects of transcatheter LAA closure
21 May 2025 – From EuroPCR 2025
Engage in case-based learning focused on transcatheter left atrial appendage (LAA) closure. This session covers safe transseptal puncture techniques, state-of-the-art standard LAA closure procedures, management of challenging LAA anatomies, and optimization of post-procedure antithrombotic therapy in high-risk patients.
Academic Research Consortium on LAA closure
21 May 2025 – From EuroPCR 2025
Gain comprehensive understanding of the Academic Research Consortium's achievements in left atrial appendage (LAA) closure. Learn how standardized endpoints are streamlined for randomized controlled trials and how collaborative efforts homogenize definitions to advance clinical research.
What are the essential aspects of transcatheter LAA closure?
20 May 2025 – From EuroPCR 2025
Ole De Backer and Philippe Garot discuss the rapid evolution of transcatheter left atrial appendage (LAA) occlusion.
They begin by contrasting patient selection in Europe and the US, where approaches diverge significantly: in Europe, very high bleeding risk remains the main criterion, while in the US, LAA...
Navigating LAA closure in retrobend chicken-wing anatomy
07 Mar 2025
A 76-year-old female patient with a history of atrial fibrillation and contraindication to long-term anticoagulation presents for left atrial appendage closure. However, preprocedural imaging reveals a challenging retrobend chicken-wing morphology. What is the best technique to optimize positioning and ensure safe, effective closure in this scenario?

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LAA occlusion in reverse chicken-wing
04 Nov 2024
Discover the case of an 82-year-old female with cardiovascular risk factors including hypertension and diabetes (managed with oral antidiabetics), permanent non-valvular atrial fibrillation, who presented with recurrent episodes of epistaxis while on anticoagulants...

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Management of LAA closure complications
16 May 2024 – From EuroPCR 2024
This session explores the various complications that can arise during left atrial appendage (LAA) closure procedures, including pericardial effusion, device embolisation, and procedural strokes. Learn how to identify risk factors, prevent these complications, and effectively manage them through case-based discussions and expert guidance.
Is this patient a good candidate for Left Atrial Appendage Closure? An interactive rapid-fire discussion
16 May 2024 – From EuroPCR 2024
This interactive session focuses on selecting good candidates for left atrial appendage (LAA) closure procedures. It covers the key clinical elements driving the indication for LAA closure and the technical elements that make a case complex. Through a series of case presentations and discussions, the session...
LAA closure - LIVE case
16 May 2024 – From EuroPCR 2024
A 78-year-old woman with hypertension, diabetes, obesity, and a history of pacemaker implantation in 2023, presented with retinal hemorrhage while on NACO for AF. Despite a CHA2DS2-VASC score of 5, anticoagulation was withdrawn. The operators implanted a Watchman device in the LAA via a venous right femoral...
Left main and complex bifurcation stenting
14 May 2024 – From EuroPCR 2024
Watch this session focused on a patient with distal left main stenosis to understand that the stepwise provisional side branch (SB) stenting strategy is the standard approach for most left main trifurcation lesions. Discover the importance of optical frequency domain imaging for strategy determination and bifurcation...