Stephen Worthley

Stephen Worthley

Interventional cardiologist / Cardiologist
Macquarie University Hospital - Sydney, Australia

Latest contributions

Complications and bailout strategies in transcatheter mitral interventions

15 Feb 2026 – From PCR Tokyo Valves 2026

This session addresses complications arising during transcatheter mitral edge-to-edge repair (TEER), focusing on identification, anticipation, and management strategies. It also highlights the importance of case selection to improve procedural safety, supported by detailed case analyses covering leaflet/device, access/septal, and hemodynamic complications.

Complications and bailout strategies in transcatheter mitral interventions

Miscellaneous complications: my worst nightmare

15 Feb 2026 – From PCR Tokyo Valves 2026

Explore the prevention and management of complications arising from transcatheter interventions in structural heart disease through challenging case analyses. This session presents real-world scenarios addressing complications encountered during TAVI, mitral, and tricuspid procedures, highlighting strategies to anticipate and manage these critical events effectively.

Miscellaneous complications: my worst nightmare

Coronary access and revascularisation in patients undergoing TAVI: from work-up to lifetime management

15 Feb 2026 – From PCR Tokyo Valves 2026

This session delves into the comprehensive management of ischemic heart disease in patients undergoing transcatheter aortic valve implantation (TAVI). It highlights the critical importance of maintaining coronary access post-TAVI and explores how various valve designs affect coronary accessibility, particularly in cases involving valve-in-valve (TAV-in-TAV) procedures, guiding...

Coronary access and revascularisation in patients undergoing TAVI: from work-up to lifetime management

Challenging scenarios in the pulmonary system - Part 2

23 May 2025 – From EuroPCR 2025

Delve into complex pulmonary interventions through cases highlighting pulmonary thrombectomy, intracavitary thrombus management, and challenges in simultaneous pulmonary embolism and ischemic stroke. This session emphasizes minimally invasive approaches and strategic decision-making in pulmonary vascular disease.

Challenging scenarios in the pulmonary system - Part 2

Leaflet modification to prevent coronary obstruction during TAVI

22 May 2025 – From EuroPCR 2025

This session addresses advanced leaflet modification techniques to prevent coronary obstruction during TAVI. Learn from detailed cases involving valve-in-valve interventions, treatment of failed stentless valves, homograft management, and dedicated devices for leaflet modification prior to valve-in-valve and valve-in-valve-in-valve procedures.

Leaflet modification to prevent coronary obstruction during TAVI

How to optimise TAVI outcomes in the Asian-Pacific population?

22 May 2025 – From EuroPCR 2025

What are the key considerations for TAVI in Asian-Pacific patients? This EuroPCR 2025 session focuses on optimising outcomes in anatomically and clinically specific contexts, such as patients with small annuli. Learn how the latest intra-annular self-expanding devices can help reduce post-procedural pacemaker implantation (PPI) rates, and...

How to optimise TAVI outcomes in the Asian-Pacific population?

New devices for structural interventions

21 May 2025 – From EuroPCR 2025

Discover emerging devices transforming structural heart interventions. This session highlights biomimetic valve designs, new transcatheter aortic valve systems, novel devices for aortic insufficiency, leaflet resection, left atrial appendage closure, and short self-expanding TAVR valves with promising early results.

New devices for structural interventions

Featured Cases - Pulmonary valve intervention

26 Nov 2024 – From PCR London Valves 2024

Explore this session featuring a selection of compelling clinical cases from PCR London Valves 2024, focusing on innovative percutaneous interventions for complex pulmonary valve pathologies. Discover how clinicians are simplifying the challenge of treating dilated main pulmonary arteries, dealing with premature balloon rupture, and tackling giant...

Featured Cases - Pulmonary valve intervention

New technology for transcather valve replacement - LIVE case

25 Nov 2024 – From PCR London Valves 2024

Watch a series of recorded cases showcasing advanced valve therapies and innovative techniques:

  • A 70-year-old man with Marfan syndrome (treated by Bentall and CABG in 2012), impaired LV function (35%), CRT-D, and symptomatic severe primary MR (A2 prolapse with calcification) underwent implantation of an Intrepid valve under...
New technology for transcather valve replacement - LIVE Case

Breaking new ground in mitral valve interventions

24 Nov 2024 – From PCR London Valves 2024

What’s shaping the future of mitral valve therapies? This video from PCR London Valves 2024 unveils groundbreaking late-breaking trials that redefine the possibilities in mitral interventions.

You'll explore real-world insights from the OCEAN-Mitral registry on the MitraClip G4, uncover the link between tricuspid regurgitation and 3-year mortality...

Breaking new ground in mitral valve interventions

Featured cases - Strategic approaches in mitral regurgitation

24 Nov 2024 – From PCR London Valves 2024

Immerse yourself in this featured session showcasing strategic approaches in the management of mitral regurgitation. Explore a range of complex cases, including percutaneous annuloplasty with a novel device in functional mitral regurgitation, the management of mitral annulus cavity and regurgitation post-healed endocarditis, simultaneous management of two...

Featured cases - Strategic approaches in mitral regurgitation

Featured research - Mitral valve (Part 1)

24 Nov 2024 – From PCR London Valves 2024

Explore the cutting edge of mitral valve research in this two-part featured research session. Dive into a diverse array of abstracts selected from the upcoming PCR London Valves 2024 conference, covering topics such as optimizing neo-left ventricular outflow tract area, addressing anatomical challenges in TMVR, the...

Featured research - Mitral valve (Part 1)

Innovations in heart failure: moving the heart forward

13 May 2024 – From EuroPCR 2024

Innovations in heart failure: moving the heart forward

EuroPCR 2023 Hotlines/Late-Breaking Trials: mitral and tricuspid valves disease

17 May 2023 – From EuroPCR 2023

The presenters share their views on a range of essays and studies. Join them for an update on: Early experience with a d-shape, monoleaflet TMVR system; Outcomes of Mitral Valve-in-Valve, Mitral Valve-in-Ring and Valve-in-Mitral Annular; Calcification: prospective MITRAL; DRAGONFLY-DMR: transcatheter repair by DragonFly device in mitral...

HighLife TSMVR and their latest experiences, moving forward

29 Nov 2022 – From PCR London Valves 2022

A panel of experts review the latest clinical data, study progress and future plans regarding mitral valve replacement, and the position of HighLife, a new technology in this field.

Transcatheter primary mitral regurgitation repair and tricuspid replacement - LIVE case

28 Nov 2022 – From PCR London Valves 2022

  • Part 1: Primary MR repair (recorded case)
    An 89-year-old male with atrial fibrillation, severe primary MR (prolapse A1-A2) with a preserved LV function. The operators implant 1 Pascal ACE, on general anaesthesia, guided by TEE.
  • Part 2: Tricuspid valve in valve (Live case)
    A 52-year-old female, with diabetes and...
Transcatheter intervention for mitral and tricuspid valve disease: state of the art

How to deal with residual or recurrent mitral regurgitation after failed surgical or transcatheter repair

28 Nov 2022 – From PCR London Valves 2022

Consul this session to learn more about the available treatment options after failed mitral surgical or transcatheter procedures, the factors that increase the likelihood of residual/recurrent mitral regurgitation, and more!

How to deal with residual or recurrent mitral regurgitation after failed surgical or transcatheter repair

TAVI – Minimising vascular complications and optimising delivery

29 Jun 2022

Watch the replay of the 1st module in this series on TAVI to discuss techniques to limit vascular complications and much more!
With Stephen Worthley, Dave Smith and Lars Sondergaard

Transcatheter mitral valve replacement

18 May 2022 – From EuroPCR 2022

In this session focusing on transcatheter mitral valve replacement, learn more about: who are the optimal patients, two clinical case examples - "meet the patient" and "a live CT analysis", and what to analyse and measure during the CT analysis.

Transcatheter mitral valve replacement

Highlife TSMVR - (Not) only for the happy few?

17 May 2022 – From EuroPCR 2022

Watch this discussion between Nicolo Piazza, Stephen Worthley and Wolfgang Rottbauer to find out more about Highlife TSMVR imaging preparation, to understand the looping procedure by manoeuvring the guidewire in the appropriate fluoroscopic views, and finally learn how to place the ring and valve delivery and...

Highlife TSMVR - (Not) only for the happy few?

HighLife TSMVR study status and new developments

22 Nov 2021 – From PCR London Valves 2021

Watch this session from the PCR London Valves 2021 Congress to find out more about HighLife systems and how it works, to witness a live recorded case presentation, to get clinical data, and to get an idea of the upcoming future alterations of the device to...

HighLife TSMVR study status and new developments