Xavier Freixa
Latest contributions
Making the complex simple: bicaval valve implantation as a rescue strategy
01 Jun 2026
An 80-year-old woman was referred for persistent right heart failure despite previous surgical mitral repair and subsequent transcatheter tricuspid intervention. Over time, she developed progressive symptoms with recurrent severe tricuspid regurgitation, refractory to optimised medical therapy.
Multimodality imaging confirmed significant right-sided chamber dilatation and complex valve anatomy,...

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Combined mitral intervention and LAA closure: LIVE Educational Case from Rigshospitalet Heart Centre - Copenhagen, Denmark
21 May 2026 – From EuroPCR 2026
This session offers a comprehensive educational experience on combined mitral intervention and LAA closure. It identifies ideal candidates, addresses procedural challenges of performing both interventions in a single session, and provides a detailed, step-by-step guide through a live case from Rigshospitalet Heart Centre.
Innovation in action: achieving optimal outcomes in mitral regurgitation
20 May 2026 – From EuroPCR 2026
A growing mitral valve portfolio is reshaping how mitral regurgitation is treated, offering tailored solutions across a broader range of patient anatomies and clinical scenarios.
This EuroPCR 2026 session focuses on innovations in transcatheter mitral therapies, highlighting how mitral transcatheter edge-to-edge repair (TEER) with the PASCAL Precision...
When to best combine guided-directed medical therapy and devices at discharge of acute heart failure
20 May 2026 – From EuroPCR 2026
This session addresses the challenges and strategies in optimizing guided-directed medical therapy for acute heart failure patients, especially those intolerant to up-titration. It also covers the assessment and timing for cardiac resynchronisation therapy (CRT), highlighting the benefits of combining medical therapy and device implantation to improve...
Insight from recent evidence in structural heart disease: indications for LAA closure (CHAMPION) and PCI in TAVI candidates (PRO-TAVI)
20 May 2026 – From EuroPCR 2026
This session reviews recent evidence impacting the management of structural heart disease, focusing on left atrial appendage (LAA) closure indications and PCI considerations in transcatheter aortic valve implantation (TAVI) candidates. It discusses optimal strategies for coronary artery disease in TAVI patients and evaluates findings from the...
How to prevent and manage complex and complicated LAA closure cases?
19 May 2026 – From EuroPCR 2026
Designed to enhance procedural success in transcatheter left atrial appendage closure, this session addresses identification of complex anatomies, management of intraprocedural challenges, and strategies to prevent and handle complications, illustrated by practical case examples and expert evaluations.
Complications of paravalvular leak closure
18 Nov 2025 – From PCR London Valves 2025
This session addresses the complexities and risks associated with paravalvular leak (PVL) closure. It offers detailed analysis of principal complications, prevention techniques, and practical management strategies shared by experienced operators. Case studies illustrate complications such as device embolisation, prosthetic valve disc impingement, and delivery failures, along...
Spotlight on a selection of top Late-breaking Trials presented at PCR London Valves 2025
17 Nov 2025
View a snapshot of the results of these 4 trials in valvular and structural interventions presented in London during this year's Heart Team Course!
Complications of LAA closure - Avoidance and management
17 Nov 2025 – From PCR London Valves 2025
Focused on the prevention and management of complications in left atrial appendage (LAA) closure, this session covers recognition of key procedural risks, techniques for safe transseptal puncture, and strategies to prevent and address device embolisation, pericardial effusion, residual leaks, and device-related thrombus, ensuring procedural safety and...
From innovation to intervention: optimising procedural techniques in tricuspid TEER
17 Nov 2025 – From PCR London Valves 2025
Explore advanced strategies for tricuspid TEER in this PCR London Valves 2025 session.
Through real-world cases and interactive simulation, learn how to optimise outcomes in complex tricuspid anatomy, manage challenges posed by pacemaker leads, and enhance procedural efficiency using the TriClip G5 device.
Gain practical insights on clipping...
Featured research - Tricuspid valve intervention: the TRIPLACE registry
17 Nov 2025 – From PCR London Valves 2025
This session features cutting-edge research on tricuspid valve interventions, including insights from the TRIPLACE registry on orthotopic TTVR thrombosis, predictive value of three-dimensional tricuspid annulus measurements for procedural outcomes, early clinical experiences with novel TTVR systems, and procedural clipping strategies based on results from the BRIGHT...
One-year results from the ADALA trial
16 Nov 2025 – From PCR London Valves 2025
Left atrial appendage (LAA) closure is a new focus at this year’s PCR London Valves Course, and, in this interview, Xavier Freixa and Christopher Allen discuss the ADALA trial and its impact on post-occlusion management.
The study compared three months of low-dose DOAC with three months of...
Late-breaking evidence in structural and coronary interventions - Part 2
16 Nov 2025 – From PCR London Valves 2025
This session presents the latest data from pivotal late-breaking trials in interventional cardiology. Highlights include one-year results from the ADALA trial, first-in-man use of the Vivasure PerQseal Elite for large hole arterial closure, two-year outcomes of the DragonFly system in China, six-month European outcomes, and insights...
LAAC: current and future indications
03 Jun 2025
Watch the replay of this webinar and learn about the evidence (current guidelines and indications) for LAAC in 2025, and so much more!
Optimal use of cardiac imaging to plan and guide transcatheter LAA closure
22 May 2025 – From EuroPCR 2025
Optimize left atrial appendage (LAA) closure outcomes through expert use of cardiac imaging. This session details the role of various imaging modalities in pre-procedural planning, intraprocedural guidance, and post-procedural assessment. Gain practical insights on transesophageal echocardiography, computed tomography, intracardiac echocardiography, and their integration to enhance procedural...
Case-based learning on different aspects of transcatheter LAA closure
21 May 2025 – From EuroPCR 2025
Engage in case-based learning focused on transcatheter left atrial appendage (LAA) closure. This session covers safe transseptal puncture techniques, state-of-the-art standard LAA closure procedures, management of challenging LAA anatomies, and optimization of post-procedure antithrombotic therapy in high-risk patients.
TEER for challenging anatomy: from myth to reality
21 May 2025 – From EuroPCR 2025
Explore advanced TEER techniques for challenging anatomies. This session covers indications, periprocedural steps, state-of-the-art procedural methods, and management of failed surgical tricuspid annuloplasty, with case discussions highlighting practical learnings for complex mitral and tricuspid interventions.
Navigating LAA closure in retrobend chicken-wing anatomy
07 Mar 2025
A 76-year-old female patient with a history of atrial fibrillation and contraindication to long-term anticoagulation presents for left atrial appendage closure. However, preprocedural imaging reveals a challenging retrobend chicken-wing morphology. What is the best technique to optimize positioning and ensure safe, effective closure in this scenario?

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Tricuspid transcatheter edge-to-edge repair - The fundamentals
25 Nov 2024 – From PCR London Valves 2024
Ready to dive into tricuspid transcatheter edge-to-edge repair (TEER)? This video breaks down the procedure by exploring real-world cases and key techniques.
Through practical case presentations, you'll gain insights into the anatomical criteria that determine suitability for TEER, the importance of imaging and haemodynamic assessments and the...
Innovation never stops: Cardiovalve in action!
24 Nov 2024 – From PCR London Valves 2024
Join us as we explore the latest advancements in transcatheter tricuspid valve replacement technologies. This session develops the anatomical and imaging challenges associated with this rapidly developing clinical field and provides an update on the Cardiovalve tricuspid clinical program, illustrated by a recorded case.
Featured cases - Challenging tricuspid interventions (Part 2)
24 Nov 2024 – From PCR London Valves 2024
Dive into this session showcasing a diverse array of challenging tricuspid interventions from the PCR London Valves 2024 Clinical Cases submissions. Discover complex cases involving TTVR in a transplanted heart, recurrent tricuspid regurgitation after T-TEER, and an extremely difficult tricuspid valve-in-valve implantation. Gain insights on navigating...
LAA occlusion in reverse chicken-wing
04 Nov 2024
Discover the case of an 82-year-old female with cardiovascular risk factors including hypertension and diabetes (managed with oral antidiabetics), permanent non-valvular atrial fibrillation, who presented with recurrent episodes of epistaxis while on anticoagulants...

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Is this patient a good candidate for Left Atrial Appendage Closure? An interactive rapid-fire discussion
16 May 2024 – From EuroPCR 2024
This interactive session focuses on selecting good candidates for left atrial appendage (LAA) closure procedures. It covers the key clinical elements driving the indication for LAA closure and the technical elements that make a case complex. Through a series of case presentations and discussions, the session...
Heterotopic tricuspid valves: to who, when and how?
15 May 2024 – From EuroPCR 2024
Watch this session to gain comprehensive insights into the use, safety, and efficacy of heterotopic tricuspid valves. Learn to identify ideal candidates with severe tricuspid regurgitation, understand key procedural factors for successful implantation, and receive tips on valve systems and anatomy. The session also includes...
How to achieve optimal results in tricuspid valve interventions?
15 May 2024 – From EuroPCR 2024
How to manage paravalvular leaks?
04 Jan 2024 – From PCR London Valves 2023
Invited to talk about paravalvular leaks, Grzegorz Smolka, Patrick Calvert and Xavier Freixa begin by placing the subject in context, mentioning the frequency with which it is encountered in general practice.
Then, they distinguish between patients likely to benefit from paravalvular leak closure via transcatheter and those...
Mitral valve intervention in complex scenarios - Transcatheter paravalvular leak closure
21 Nov 2023 – From PCR London Valves 2023
Everything you need to know about mitral PVL and transcatheter closure is outlined in this session: clinical implications, indications for transcatheter closure, role of imaging, necessary access and equipment, and even tips for difficult anatomies.
EuroPCR 2023 Hotlines/Late-Breaking Trials: TAVI, hypertension, stroke prevention
17 May 2023 – From EuroPCR 2023
Want to find out what's happened lately in the field of hypertension and stroke prevention with TAVI? Check out this session where speakers give their take on what's essential to remember from a selection of studies: Primary outcome of the AnchorMan LAAO device randomised controlled trial...
Heterotopic valve replacement for patients with right heart failure and tricuspid regurgitation - All you need to know!
17 May 2023 – From EuroPCR 2023
Discover the comprehensive guide to heterotopic valve replacement for patients experiencing right heart failure and tricuspid regurgitation. Join this session to gain insights into patient selection criteria, delve into the concept behind this innovative procedure, and grasp the fundamental aspects of its execution.
Percutaneous LAA closure 2.0
17 May 2023 – From EuroPCR 2023
In these slides, delve into advanced Percutaneous LAA Closure 2.0. Optimise procedure planning, grasp key post-procedural follow-up aspects, master essential tips for WatchmanFLX and Amulet device implantation, and much more.