Left main and multivessel disease

Find all the latest content on left main and multivessel disease published on this website.

The left main coronary artery provides the primary source of blood flow to the left ventricle. Diseases affecting the left main, by itself or in combination with multivessel disease, place the patient at significant risk for life-threatening cardiovascular events. Treatment requires an understanding of all available tools, devices and techniques, like those employed in invasive imaging and functional assessment, as well as taking into account underlying comorbidities such as diabetes. Advances in imaging techniques, as well as the use of adjunctive pharmacotherapy, vascular access or invasive interventions such as bypass surgery, are important, as are understanding bleeding risks. Use the filters below to access PCRonline resources.

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Left main and multivessel disease

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Safety of Revascularization Deferral of Left Main Stenosis Based on Instantaneous Wave-Free Ratio Evaluation

05 Aug 2020

The main message appears to be that iFR-based deferral of LM revascularization is not linked to an excessive risk of MACE during 30-month median follow-up. Given the historical predominance of angiography-based decision making, this study provides further evidence in support of thinking and acting beyond angiography...

Dejan Milasinovic

Reviewer

Dejan Milasinovic
Safety of Revascularization Deferral of Left Main Stenosis Based on Instantaneous Wave-Free Ratio Evaluation

Multicentre, randomised comparison of two-stent and provisional stenting techniques in patients with complex coronary bifurcation lesions: the DEFINITION II trial

22 Jul 2020

DEFINITION-II adds to the evidence that an upfront 2-stent strategy may be most appropriate in true complex bifurcation lesions.

Nicola Ryan

Reviewer

Nicola Ryan
DEFINITION II trial: comparison of two-stent and provisional stenting techniques in patients with complex coronary bifurcation lesions

Ultra low contrast: new skills and technologies for next frontier in PCI

27 Jun 2020 – From PCR e-Course 2020

Watch this session if you want to learn why ULCPCI will be needed for patients who have developed cardiomyopathy due wait linked to COVID outbreak, to understand what tools we have in the cathlab to perform ULCPCI and to learn how to practice ultra-low contrast in...

Ultra low contrast: new skills and technologies for next frontier in PCI

CABG or PCI in patients with left main coronary artery disease

27 Jun 2020 – From PCR e-Course 2020

Watch this session if you want to be updated on clinical outcomes in patients with left main lesion treated by PCI or CABG and to understand the different criteria who play a major role in decision making between PCI and CABG.

This session was originally presented during...

CABG or PCI in patients with left main coronary artery disease

Non-culprit stenosis revascularisation in STEMI patients with multivessel disease: which, when and how?

26 Jun 2020 – From PCR e-Course 2020

Watch this case discussion if you want to understand how to invasively evaluate non-culprit stenosis in STEMI, to discuss optimal timing of non-culprit PCI and to understand how to implement novel evidence and guideline recommendations to your local practice.

This session was originally presented during PCR e-Course...

Non-culprit stenosis revasc. in STEMI patients with MVD: which, when and how?

CT guidance for coronary interventions - PCR e-Course 2020 Hot lines

26 Jun 2020 – From PCR e-Course 2020

Watch a series of Hot Lines on CT-guidance for PCI presented during the PCR e-Course 2020, followed by an analysis of the results and their impact on your practice: CT-FFR CHINA, CAST-FFR, CT-QFR vs. myocardial perfusion imaging, CT-CTO trial, CCTA for optimal fluoroscopic coronary projections.

CT guidance for coronary interventions

PCR e-Course 2020 Late-Breaking Trials - part 2

26 Jun 2020 – From PCR e-Course 2020

Watch a series of Late-Breaking Trials presented during the PCR e-Course 2020 and see how they might have an impact on your practice: 

  • 2-year safety of revascularisation deferral based on iFR or FFR
  • CABG and PCI in patients with CTO and multivessel disease
  • Routine revascularisation vs. medical therapy
PCR e-Course 2020 Late-Breaking Trials

SYNERGY MEGATRON - Transforming your left main bifurcation strategy for improved outcomes

Watch this session if you want to review steps for PCI in complex left main bifurcation lesions, to advance your knowledge on IVUS-guided PCI in left main disease and to learn about a purpose-built new stent platform for large vessels and left main.

SYNERGY MEGATRON - Transforming your left main bifurcation strategy for improved outcomes

Hotlines and innovations on left main & multivessel disease - PCR e-Course 2020

25 Jun 2020 – From PCR e-Course 2020

View a selection of hot lines from PCR e-Course 2020 on the topic of left main & multivessel disease:

  • One-year clinical outcomes of complex PCI treated with use of Ultimaster stent
  • Impact of residual SYNTAX score on all-cause death at 10 yrs in the SYNTAX trial
Hotlines and innovations on left main & multivessel disease

PCR e-Course 2020 Clinical cases

25 Jun 2020 – From PCR e-Course 2020

Watch a series of best clinical cases presented at the PCR e-Course 2020:

  • ACS-patient with culprit in a coronary ectasia
  • Coronary stenting in an ectatic artery
  • Challenging PCI after aortic valve-in-valve implantation
  • Cisplatin-induced coronary artery thrombosis presented as ACS
  • MOCA I study: microvascular obstruction measured using dMVR
  • The many faces of in-stent...
PCR e-Course Clinical cases