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Left main and multivessel disease

Find all the latest content on left main and multivessel disease published on this website.

The left main coronary artery provides the primary source of blood flow to the left ventricle. Diseases affecting the left main, by itself or in combination with multivessel disease, place the patient at significant risk for life-threatening cardiovascular events. Treatment requires an understanding of all available tools, devices and techniques, like those employed in invasive imaging and functional assessment, as well as taking into account underlying comorbidities such as diabetes. Advances in imaging techniques, as well as the use of adjunctive pharmacotherapy, vascular access or invasive interventions such as bypass surgery, are important, as are understanding bleeding risks. Use the filters below to access PCRonline resources.

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Left main and multivessel disease

422 results

Ten-year outcomes after DES versus CABG for LM coronary disease: extended follow-up of the PRECOMBAT trial

27 Apr 2020

This 10-year follow-up of the randomised PRECOMBAT trial adds to the already published long-term randomised comparisons of PCI vs. CABG for LM disease, including the data from SYNTAX (10 years), EXCEL (5 years) and NOBLE (5 years) trials.

Dejan Milasinovic

Reviewer

Dejan Milasinovic
Updated pooled analysis of long-term all-cause mortality after PCI vs CABG for LM disease

Impact of kissing balloon in patients treated with ultrathin stents for left main lesions and bifurcations: an analysis from the RAIN-CARDIOGROUP VII study

26 Mar 2020

The objective of this analysis was to investigate the potential benefits of FKI in bifurcations treated with new generation ultrathin stents using a 1- or 2-stent technique.

Reviewer

Ali Nazmi Calik
Panagiotis Xaplanteris

Reviewer

Panagiotis Xaplanteris
Impact of kissing balloon in patients treated with ultrathin stents for left main lesions and bifurcations: an analysis from the RAIN-CARDIOGROUP VII study

Cardiac Surgery and the COVID-19 outbreak: what does it mean?

25 Mar 2020

A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak has been declared a Public Health Emergency of International Concern by the WHO since January 2020. The rapid, exponential, increase in confirmed cases makes prevention and control of coronavirus disease (COVID-19) extremely critical. Although clinical manifestations of...

Peter Matt

Author

Peter Matt
Prof. Francesco Maisano

Author

Francesco Maisano
Which cardiac operations should be performed ?

Essential reading for understanding data in meta-analyses

23 Mar 2020

A good systematic review and meta-analysis can be a great help in sorting out apparently conflicting studies. But the results of meta-analyses themselves can vary. We need more people to be able to read them critically, and to see why meta-analyses become conflicting results themselves.

Essential reading for understanding data in meta-analyses

Observing an aorto-ostial lesion using TELESCOPE® in optical coherence tomography-guided percutaneous coronary intervention

17 Mar 2020

In OCT-guided PCI, observing an aorto-ostial lesion is impossible as it requires blood clearance, and the material of the guiding catheter used is not near-infrared transparent. Using a Telescope®-guiding extension catheter, the authors successfully acquired an OCT image throughout the soft polymer tip and the relatively wide...

Image in cardiology: Aorto-ostial lesion observation by OCT

Mortality after drug-eluting stents vs. coronary artery bypass grafting for left main coronary artery disease: a meta-analysis of randomized controlled trials

17 Mar 2020

This metanalysis demonstrates similar long-term mortality after PCI with DES compared with CABG in patients with LMCAD. Nor were there significant differences in cardiac death, stroke, or MI between PCI and CABG. Unplanned revascularization procedures were less common after CABG compared with PCI.

Reviewer

Salvatore Brugaletta
Mortality after drug-eluting stents vs CABG for left main coronary artery disease

Management of multi-vessel calcified coronary artery disease in acute myocardial infarction complicated by cardiogenic shock

17 Mar 2020

View this case of a 79-year-old woman complaining of atypical chest pain for 3 months, with diabetes and end-stage chronic kidney disease. Coronary CT revealed diffuse calcifications BUT critical coronary artery stenosis was excluded...

Author

Flavio Luciano Ribichini
Gabriele Pesarini

Author

Gabriele Pesarini
Management of multi-vessel calcified CAD in AMI complicated by cardiogenic shock

The application of predefined optimisation criteria for intravascular ultrasound guidance of left main stenting improves outcomes

16 Mar 2020

This registry-based analysis evaluated the impact of standardisation of IVUS guidance on the results of LM PCI.

Dejan Milasinovic

Reviewer

Dejan Milasinovic
The application of predefined optimisation criteria for intravascular ultrasound guidance of LM stenting improves outcomes

Intravascular imaging and 12-month mortality after unprotected left main stem PCI : an analysis from the British Cardiovascular Intervention Society database

20 Feb 2020

This retrospective analysis of the BCIS nationwide database compares the outcomes of unprotected left main PCI with and without the use of intravascular imaging (IVUS or OCT).

Dejan Milasinovic

Reviewer

Dejan Milasinovic
Panagiotis Xaplanteris

Reviewer

Panagiotis Xaplanteris
Intravascular imaging and 12-month mortality after unprotected left main stem PCI: an analysis from the BCIS database

Mortality after repeat revascularization following PCI or coronary artery bypass grafting for left main disease: The EXCEL Trial

05 Feb 2020

This study is a sub-analysis of the EXCEL (Evaluation of XIENCE Versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization) trial. Its aim is to evaluate the rate and impact of repeat revascularization of the Left Main coronary artery using modern PCI or surgical...

Dr. Mirvat Alasnag

Reviewer

Mirvat Alasnag
Khaled F. Al-Shaibi

Reviewer

Khaled Al-Shaibi
Mortality after repeat revascularization following PCI or CABG for left main disease