Left main and multivessel disease

Find all the latest content on left main and multivessel disease published on this website.

The left main coronary artery provides the primary source of blood flow to the left ventricle. Diseases affecting the left main, by itself or in combination with multivessel disease, place the patient at significant risk for life-threatening cardiovascular events. Treatment requires an understanding of all available tools, devices and techniques, like those employed in invasive imaging and functional assessment, as well as taking into account underlying comorbidities such as diabetes. Advances in imaging techniques, as well as the use of adjunctive pharmacotherapy, vascular access or invasive interventions such as bypass surgery, are important, as are understanding bleeding risks. Use the filters below to access PCRonline resources.

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Left main and multivessel disease

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The unique challenges of left main PCI

Watch this session if you want to understand why the left main PCI approach and techniques are unique to the anatomy, to understand the EBC consensus and other evidence on left main PCI and to review a left main PCI real world case.

Speakers: Goran Stankovic, Francesco...

The unique challenges of left main PCI

Are higher operator volumes for unprotected left main stem percutaneous coronary intervention associated with improved patient outcomes?

15 Jun 2020

The presented results appear to further strengthen the notion that operator’s experience may be an important effect modifier in LM PCI.

Dejan Milasinovic

Reviewer

Dejan Milasinovic
Are higher operator volumes for unprotected LM stem PCI associated with improved patient outcomes?

Multi- vs culprit-vessel percutaneous coronary intervention in cardiogenic shock

04 May 2020

This study compares outcomes of patients enrolled in the National Cardiogenic Shock Initiative (NCSI) registry treated using a strategy of MV-PCI vs CV-PCI and examines outcomes in patients treated with early MCS.

Dr. Mirvat Alasnag

Reviewer

Mirvat Alasnag
Multi- vs culprit-vessel PCI in cardiogenic shock

PCR on Call : a patient with ACS and multivessel disease: the human factor

28 Apr 2020

View the discussion of this case between Salvatore Brugaletta, Kalaivani Mahadevan and Thomas Johnson.

PCR on Call -  A COVID(+) patient with ACS and MVD: the human factor

Ten-year outcomes after DES versus CABG for LM coronary disease: extended follow-up of the PRECOMBAT trial

27 Apr 2020

This 10-year follow-up of the randomised PRECOMBAT trial adds to the already published long-term randomised comparisons of PCI vs. CABG for LM disease, including the data from SYNTAX (10 years), EXCEL (5 years) and NOBLE (5 years) trials.

Dejan Milasinovic

Reviewer

Dejan Milasinovic
Updated pooled analysis of long-term all-cause mortality after PCI vs CABG for LM disease

Impact of kissing balloon in patients treated with ultrathin stents for left main lesions and bifurcations: an analysis from the RAIN-CARDIOGROUP VII study

26 Mar 2020

The objective of this analysis was to investigate the potential benefits of FKI in bifurcations treated with new generation ultrathin stents using a 1- or 2-stent technique.

Reviewer

Ali Nazmi Calik
Panagiotis Xaplanteris

Reviewer

Panagiotis Xaplanteris
Impact of kissing balloon in patients treated with ultrathin stents for left main lesions and bifurcations: an analysis from the RAIN-CARDIOGROUP VII study

Cardiac Surgery and the COVID-19 outbreak: what does it mean?

25 Mar 2020

A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak has been declared a Public Health Emergency of International Concern by the WHO since January 2020. The rapid, exponential, increase in confirmed cases makes prevention and control of coronavirus disease (COVID-19) extremely critical. Although clinical manifestations of...

Peter Matt

Author

Peter Matt
Prof. Francesco Maisano

Author

Francesco Maisano
Which cardiac operations should be performed ?

Essential reading for understanding data in meta-analyses

23 Mar 2020

A good systematic review and meta-analysis can be a great help in sorting out apparently conflicting studies. But the results of meta-analyses themselves can vary. We need more people to be able to read them critically, and to see why meta-analyses become conflicting results themselves.

Essential reading for understanding data in meta-analyses

Observing an aorto-ostial lesion using TELESCOPE® in optical coherence tomography-guided percutaneous coronary intervention

17 Mar 2020

In OCT-guided PCI, observing an aorto-ostial lesion is impossible as it requires blood clearance, and the material of the guiding catheter used is not near-infrared transparent. Using a Telescope®-guiding extension catheter, the authors successfully acquired an OCT image throughout the soft polymer tip and the relatively wide...

Image in cardiology: Aorto-ostial lesion observation by OCT

Mortality after drug-eluting stents vs. coronary artery bypass grafting for left main coronary artery disease: a meta-analysis of randomized controlled trials

17 Mar 2020

This metanalysis demonstrates similar long-term mortality after PCI with DES compared with CABG in patients with LMCAD. Nor were there significant differences in cardiac death, stroke, or MI between PCI and CABG. Unplanned revascularization procedures were less common after CABG compared with PCI.

Reviewer

Salvatore Brugaletta
Mortality after drug-eluting stents vs CABG for left main coronary artery disease