LAA (Left Atrial Appendage) closure

Find all the latest content on left atrial appendage (LAA) published on this website.

Today, with an aging population, atrial fibrillation is more common and carries with it an increased risk of embolic cerebrovascular accidents. Anticoagulation strategies alone are not sufficient, and as a large proportion of the thrombus involved in these cerebrovascular accidents are seen to arise in the left atrial appendage (LAA), its closure, either surgically or by percutaneous methods, could reduce risk. Learn more about imaging, tools, devices and techniques as well as adjunctive pharmacotherapy, vascular access and bleeding here…

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LAA closure

103 results

Mastering simple and complex LAA closure: a step-by-step case-based approach

16 Nov 2025 – From PCR London Valves 2025

This case-based session offers a comprehensive approach to mastering left atrial appendage (LAA) closure, emphasizing the critical role of imaging from pre-procedural planning through execution. It covers patient selection, procedural strategies from experienced operators, device selection tailored to anatomy, and nuanced decision-making during challenging device releases...

Mastering simple and complex LAA closure: a step-by-step case-based approach

Featured research - Left atrial appendage occlusion and paravalvular leak closure

16 Nov 2025 – From PCR London Valves 2025

This featured research session delves into innovative transcatheter interventions including left atrial appendage occlusion and paravalvular leak closure. It covers clinical and hemodynamic outcomes of atrial shunting in heart failure, endothelialisation issues post-paravalvular leak closure, and long-term patient follow-up. Advanced guidance modalities and simulation technologies for...

Open design, confident delivery - How a novel LAA closure device provides predictable outcomes in complex anatomical settings

16 Nov 2025 – From PCR London Valves 2025

This session highlights a novel left atrial appendage (LAA) closure device featuring an open-cage design that delivers predictable clinical and procedural outcomes. It discusses the device's advantages in managing complex anatomical variations and presents implantation techniques across diverse anatomies to improve safety and efficacy.

Open design, confident delivery - How a novel LAA closure device provides predictable outcomes in complex anatomical settings

Ten trials from AHA 2025

12 Nov 2025

Alessandro Sticchi provides us with a curated overview of the late-breaking trials he found most relevant for interventional cardiologists from AHA 2025.

Alessandro Sticchi

Author

Alessandro Sticchi
Ten trials from AHA 2025

Left atrial appendage occlusion

02 Oct 2025

This PCR Textbook chapter reviews the underlying concepts involving atrial fibrillation, outlines anticoagulation strategies for thromboembolism prevention, and describes the current state and future directions of left atrial appendage occlusion.

Authors :

Jessica V. Kaczmarek, Daniel H. Steinberg, Nicholas S. Amoroso, Stefan Bertog, Jennifer Franke, Iris Grunwald, Horst Sievert
Left atrial appendage occlusion

The expanding practice of LAAC today in case examples

01 Oct 2025

Watch this replay with M. Joner, M. Lange and B. Schmidt to understand current indications for left atrial appendage occlusion in clinical practice and so much more!

The expanding practice of LAAC today in case examples

Seal the deal: echocardioraphy-guided LAA closure for stroke defense

12 Sep 2025 – From PCR Rio Valves 2025

This session focuses on echocardiography-guided left atrial appendage (LAA) closure as a critical strategy for stroke prevention. Attendees will explore optimal cardiac imaging techniques tailored to evolving clinical needs and seasonal considerations. The session also includes comprehensive instruction on post-procedural echocardiographic assessment and post-processing workflows in...

Structural heart: demanding anatomies, difficult situations and unusual strategies

12 Sep 2025 – From PCR Rio Valves 2025

Navigate complex structural heart interventions through this session focusing on challenging anatomies and innovative procedural strategies. Topics include orthotopic tricuspid valve replacement amidst anatomical and physiological complexities, percutaneous closure of Valsalva sinus fistula, extreme TAVI approaches for pure aortic regurgitation, management of mitral paravalvular leaks with...

Redefining and optimising LAA closure - LIVE Case

11 Sep 2025 – From PCR Rio Valves 2025

Supported by an unrestricted educational grant from Boston Scientific

A 78-year-old woman with atrial fibrillation and obesity (BMI 34.3), normal left ventricular function, CHADS-VASCs 5 and HAS-BLED 4, presented with severe gastrointestinal bleeding.

She underwent implantation of a Watchman FLX™ pro under local anesthesia via two right femoral...

Redefining and optimising LAA closure - LIVE Case

Sealing the risk: a case of left atrial appendage closure

15 Sep 2025

A 76-year-old woman with permanent atrial fibrillation, a history of breast cancer, and a recent diagnosis of an intestinal stromal tumour presents with a high thromboembolic and bleeding risk, making long-term anticoagulation unsafe. Cardiac CT reveals a challenging left atrial appendage anatomy. How would you treat this...

Sergio Berti

Author

Sergio Berti
Giovanni Benedetti

Author

Giovanni Benedetti
Luigi Emilio Pastormerlo

Author

Luigi Emilio Pastormerlo
Augusto Eposito

Author

Augusto Eposito
Marta Casula

Author

Marta Casula
Sealing the risk: a case of left atrial appendage closure