LAA (Left Atrial Appendage) closure

Find all the latest content on left atrial appendage (LAA) published on this website.

Today, with an aging population, atrial fibrillation is more common and carries with it an increased risk of embolic cerebrovascular accidents. Anticoagulation strategies alone are not sufficient, and as a large proportion of the thrombus involved in these cerebrovascular accidents are seen to arise in the left atrial appendage (LAA), its closure, either surgically or by percutaneous methods, could reduce risk. Learn more about imaging, tools, devices and techniques as well as adjunctive pharmacotherapy, vascular access and bleeding here…

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LAA closure

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LAA closure is evolving: are you ready?

17 Nov 2025 – From PCR London Valves 2025

This session addresses the evolving landscape of left atrial appendage (LAA) closure in stroke prevention for atrial fibrillation patients. It reviews unmet clinical needs, evaluates the latest evidence and guideline recommendations, and identifies patient populations that benefit most from LAA closure, with discussions on balancing efficacy...

LAA closure is evolving: are you ready?

Mitral TEER and LAA closure - LIVE Case

17 Nov 2025 – From PCR London Valves 2025

Watch a LIVE case followed by a recorded case regarding a 91-year-old female with permanent AF, LAD PCI three months earlier, and recurrent GID bleeding who presented with symptomatic severe primary mitral regurgitation due to P2 prolapse and flail. CT imaging showed a LAA with a...

Mitral TEER and LAA closure -  LIVE Case

The next frontier in LAA closure: innovations and opportunities

17 Nov 2025 – From PCR London Valves 2025

Explore the forefront of left atrial appendage (LAA) closure with this session focusing on the latest innovations and clinical opportunities. Topics include recent data on WATCHMAN FLX PRO and VersaCross Connect systems, workflow strategies to improve procedural efficiency, and discussions on upcoming clinical trials such as...

The next frontier in LAA closure: innovations and opportunities

What are the key steps in pre procedural assessment for successful LAA closure?

16 Nov 2025 – From PCR London Valves 2025

Lorenz Räber and Kasper Korsholm highlight why pre-procedural imaging—particularly cardiac CT—has become essential for successful left atrial appendage occlusion (LAAO). They explain that the LAA is highly variable between patients, making detailed planning crucial for safety, device selection, and optimal procedural results.

This interview was filmed at...

What are the key steps in pre procedural assessment for successful LAA closure?

One-year results from the ADALA trial

16 Nov 2025 – From PCR London Valves 2025

Left atrial appendage (LAA) closure is a new focus at this year’s PCR London Valves Course, and, in this interview, Xavier Freixa and Christopher Allen discuss the ADALA trial and its impact on post-occlusion management.

The study compared three months of low-dose DOAC with three months of...

One-year results from the ADALA tria

Late-breaking evidence in structural and coronary interventions - Part 2

16 Nov 2025 – From PCR London Valves 2025

This session presents the latest data from pivotal late-breaking trials in interventional cardiology. Highlights include one-year results from the ADALA trial, first-in-man use of the Vivasure PerQseal Elite for large hole arterial closure, two-year outcomes of the DragonFly system in China, six-month European outcomes, and insights...

The Top Late-Breaking Trials - Part 2

Open design, confident delivery - How a novel LAA closure device provides predictable outcomes in complex anatomical settings

16 Nov 2025 – From PCR London Valves 2025

This session highlights a novel left atrial appendage (LAA) closure device featuring an open-cage design that delivers predictable clinical and procedural outcomes. It discusses the device's advantages in managing complex anatomical variations and presents implantation techniques across diverse anatomies to improve safety and efficacy.

Open design, confident delivery - How a novel LAA closure device provides predictable outcomes in complex anatomical settings

Featured research - Left atrial appendage occlusion and paravalvular leak closure

16 Nov 2025 – From PCR London Valves 2025

This featured research session delves into innovative transcatheter interventions including left atrial appendage occlusion and paravalvular leak closure. It covers clinical and hemodynamic outcomes of atrial shunting in heart failure, endothelialisation issues post-paravalvular leak closure, and long-term patient follow-up. Advanced guidance modalities and simulation technologies for...

Mastering simple and complex LAA closure: a step-by-step case-based approach

16 Nov 2025 – From PCR London Valves 2025

This case-based session offers a comprehensive approach to mastering left atrial appendage (LAA) closure, emphasizing the critical role of imaging from pre-procedural planning through execution. It covers patient selection, procedural strategies from experienced operators, device selection tailored to anatomy, and nuanced decision-making during challenging device releases...

Mastering simple and complex LAA closure: a step-by-step case-based approach

Ten trials from AHA 2025

12 Nov 2025

Alessandro Sticchi provides us with a curated overview of the late-breaking trials he found most relevant for interventional cardiologists from AHA 2025.

Alessandro Sticchi

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Alessandro Sticchi
Ten trials from AHA 2025