LAA (Left Atrial Appendage) closure

Find all the latest content on left atrial appendage (LAA) published on this website.

Today, with an aging population, atrial fibrillation is more common and carries with it an increased risk of embolic cerebrovascular accidents. Anticoagulation strategies alone are not sufficient, and as a large proportion of the thrombus involved in these cerebrovascular accidents are seen to arise in the left atrial appendage (LAA), its closure, either surgically or by percutaneous methods, could reduce risk. Learn more about imaging, tools, devices and techniques as well as adjunctive pharmacotherapy, vascular access and bleeding here…

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LAA closure

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One-year results from the ADALA trial

16 Nov 2025 – From PCR London Valves 2025

Left atrial appendage (LAA) closure is a new focus at this year’s PCR London Valves Course, and, in this interview, Xavier Freixa and Christopher Allen discuss the ADALA trial and its impact on post-occlusion management.

The study compared three months of low-dose DOAC with three months of...

One-year results from the ADALA tria

Mastering simple and complex LAA closure: a step-by-step case-based approach

16 Nov 2025 – From PCR London Valves 2025

This case-based session offers a comprehensive approach to mastering left atrial appendage (LAA) closure, emphasizing the critical role of imaging from pre-procedural planning through execution. It covers patient selection, procedural strategies from experienced operators, device selection tailored to anatomy, and nuanced decision-making during challenging device releases...

Mastering simple and complex LAA closure: a step-by-step case-based approach

Open design, confident delivery - How a novel LAA closure device provides predictable outcomes in complex anatomical settings

16 Nov 2025 – From PCR London Valves 2025

This session highlights a novel left atrial appendage (LAA) closure device featuring an open-cage design that delivers predictable clinical and procedural outcomes. It discusses the device's advantages in managing complex anatomical variations and presents implantation techniques across diverse anatomies to improve safety and efficacy.

Open design, confident delivery - How a novel LAA closure device provides predictable outcomes in complex anatomical settings

Late-breaking evidence in structural and coronary interventions - Part 2

16 Nov 2025 – From PCR London Valves 2025

This session presents the latest data from pivotal late-breaking trials in interventional cardiology. Highlights include one-year results from the ADALA trial, first-in-man use of the Vivasure PerQseal Elite for large hole arterial closure, two-year outcomes of the DragonFly system in China, six-month European outcomes, and insights...

The Top Late-Breaking Trials - Part 2

Featured research - Left atrial appendage occlusion and paravalvular leak closure

16 Nov 2025 – From PCR London Valves 2025

This featured research session delves into innovative transcatheter interventions including left atrial appendage occlusion and paravalvular leak closure. It covers clinical and hemodynamic outcomes of atrial shunting in heart failure, endothelialisation issues post-paravalvular leak closure, and long-term patient follow-up. Advanced guidance modalities and simulation technologies for...

Ten trials from AHA 2025

12 Nov 2025

Alessandro Sticchi provides us with a curated overview of the late-breaking trials he found most relevant for interventional cardiologists from AHA 2025.

Alessandro Sticchi

Author

Alessandro Sticchi
Ten trials from AHA 2025

Left atrial appendage occlusion

02 Oct 2025

This PCR Textbook chapter reviews the underlying concepts involving atrial fibrillation, outlines anticoagulation strategies for thromboembolism prevention, and describes the current state and future directions of left atrial appendage occlusion.

Authors :

Jessica V. Kaczmarek, Daniel H. Steinberg, Nicholas S. Amoroso, Stefan Bertog, Jennifer Franke, Iris Grunwald, Horst Sievert
Left atrial appendage occlusion

The expanding practice of LAAC today in case examples

01 Oct 2025

Watch this replay with M. Joner, M. Lange and B. Schmidt to understand current indications for left atrial appendage occlusion in clinical practice and so much more!

The expanding practice of LAAC today in case examples

Seal the deal: echocardioraphy-guided LAA closure for stroke defense

12 Sep 2025 – From PCR Rio Valves 2025

This session focuses on echocardiography-guided left atrial appendage (LAA) closure as a critical strategy for stroke prevention. Attendees will explore optimal cardiac imaging techniques tailored to evolving clinical needs and seasonal considerations. The session also includes comprehensive instruction on post-procedural echocardiographic assessment and post-processing workflows in...

Structural heart: demanding anatomies, difficult situations and unusual strategies

12 Sep 2025 – From PCR Rio Valves 2025

Navigate complex structural heart interventions through this session focusing on challenging anatomies and innovative procedural strategies. Topics include orthotopic tricuspid valve replacement amidst anatomical and physiological complexities, percutaneous closure of Valsalva sinus fistula, extreme TAVI approaches for pure aortic regurgitation, management of mitral paravalvular leaks with...