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Featured research - TAVI: procedural optimization

17 Nov 2025 – From PCR London Valves 2025

Delve into comprehensive analyses of TAVI procedural outcomes and innovations in this session. Topics include the impact of intercoronary angles on coronary overlap with Evolut valves, mechanisms behind superior outcomes with the latest balloon-expandable valves, and predictive modeling of hemodynamics using physics-enhanced digital twins. Additionally, sex-specific...

Featured research - TAVI: procedural optimization

TAVI: high coronary risk - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session addresses the challenges and solutions related to high coronary risk in TAVI procedures. Topics include advanced coronary protection strategies, innovative approaches to complex valve-in-valve interventions, the benefits of balloon-assisted techniques, management of right coronary cusp obstruction through UNICORN technology, and prevention of sinus sequestration...

TAVI: complex vascular access - Part 2

17 Nov 2025 – From PCR London Valves 2025

Focus on complex vascular access challenges in TAVI with this session covering strategies such as the pave and crack technique for inaccessible vessels, management of bicuspid aortic stenosis with hostile access and horizontal aorta, complex single transfemoral access procedures, and combined interventions including left atrial appendage...

Paravalvular leaks and VSD percutaneous closure - Recorded cases

17 Nov 2025 – From PCR London Valves 2025

Recorded case 1: A 56-year-old female with a prior mechanical mitral valve replacement (Star GK, 2018), permanent AF, and normal LV function presented with recurrent HF admissions due to paravalvular leaks. She was treated with implantation of multiple plugs via a transseptal approach using a Destination...

Paravalvular leaks and VSD percutaneous closure - Recorded cases

Tricuspid valve interventions in complex scenarios - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session delves into transcatheter interventions for the tricuspid valve in complex clinical scenarios. It covers techniques for native annular reduction via TEER, management of lead-related regurgitation, challenging cases of torrential regurgitation with device detachment, and innovative methods facilitating valve-in-ring implantation, enhancing procedural efficacy in tricuspid...

Cardiogenic shock: transcatheter solutions

17 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter solutions for cardiogenic shock, highlighting rescue therapies such as mitral clip intervention in hypertrophic obstructive cardiomyopathy, valve-in-valve TAVI during CPR, and sequential mechanical circulatory support. It presents complex clinical cases illustrating stepwise approaches combining mechanical support and percutaneous valve repair to...

Leaflet modification techniques: latest acronyms, concepts and best practice

17 Nov 2025 – From PCR London Valves 2025

Gain comprehensive insights into leaflet modification techniques with a focus on the latest acronyms, concepts, and best practices. This session covers step-by-step approaches to transcatheter electrosurgical leaflet modification, including BASILICA, SHORTCUT, and UNICORN, alongside troubleshooting strategies and the innovative SURPLUS surgical technique.

Leaflet modification techniques: latest acronyms, concepts and best practice

ECLS-SHOCK: venoarterial membrane oxygenation in cardiogenic shock

27 Aug 2023

Panos Xaplanteris & Leonidas Koliastasis provide their take on the final results of the ECLS-SHOCK (Extracorporeal Life Support in Infarct-Related Cardiogenic Shock) which were presented by Holger Thiele during the ESC 2023 congress in Amsterdam.

Panagiotis Xaplanteris

Author

Panagiotis Xaplanteris

Author

Leonidas Koliastasis
ECLS-SHOCK

Predicting the unpredictable: application of predictive modeling in complex transcatheter aortic valve replacement

13 Dec 2023

This case highlights the potential add-on value of reduced-order computational modeling over standard CT scan analysis due to its ability to predict the interaction of different devices or sizes with the patient-specific anatomy.

Predicting the unpredictable: application of predictive modeling in complex transcatheter aortic valve replacement

RESHAPE-HF2 - Percutaneous repair of moderate-to-severe or severe functional mitral regurgitation in patients with symptomatic heart failure

01 Sep 2024

Nicola Ryan provides her take on the RESHAPE-HF2 trial presented by Stefan Anker at the ESC Congress 2024 in London and simultaneously published in the NEJM.

The RESHAPE-HF 2 trial is a prospective randomised control trial comparing transcatheter mitral valve repair (TEER) and guideline-directed medical therapy to guideline-directed medical...

Nicola Ryan

Author

Nicola Ryan
RESHAPE-HF2

iFR versus angiography-guided CABG: 3-year results of the iCABG randomised trial

31 Oct 2025

Alex Sticchi provides his take on the iCABG trial presented by Rasa Ordiene at TCT 2025, in San Francisco.

Alessandro Sticchi

Author

Alessandro Sticchi
iFR versus angiography-guided CABG: 3-year results of the iCABG randomized trial
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