This session focuses on technical decision-making for chronic total occlusion PCI strategy. It presents diverse approaches to right coronary CTOs, complex management involving double rendezvous techniques, subintimal strategies, and innovative single-injection methods, demonstrating the evolving frontiers in CTO intervention.

This session addresses the unique challenges encountered during transcatheter aortic valve implantation (TAVI) in patients with bicuspid aortic valves. It covers procedural nuances for type 0 bicuspid valves, risks associated with anomalous coronary anatomy, and complex anatomical considerations such as large annulus and tortuous aorta, culminating...

Addressing the complexities of PCI in bifurcation lesions, this session highlights novel techniques such as the TAP and modified mini-crush methods, alongside strategies for managing challenging coronary anatomy. Validation of novel approaches like POT-side DCB-POT for left main bifurcations is also featured.

This session examines the role of cardiac computed tomography (CT) coronary angiography in improving clinical practice for asymptomatic high-risk patients. It discusses detection of vulnerable plaque features, the importance of inflammation and physiology in risk assessment, and explores individualized treatment pathways including PCI, medical therapy, or...

This session investigates complications encountered during primary percutaneous coronary interventions (PCI). It covers management of no-reflow phenomena, innovative guide extension catheter aspiration techniques for thrombus-rich STEMI, challenges when balloon crossing fails, vein graft PCI pitfalls, and complex concurrent ischemic events involving myocardial infarction and limb ischemia....

This session provides an in-depth review of contemporary management of aortic stenosis, covering diagnostic advancements, temporal trends, and treatment outcomes. It includes insights from the LAPLACE-TAVI registry focusing on low-risk patients, discusses the growing feasibility of day-case TAVI procedures, compares transcatheter and surgical valve replacements in...

This session delves into managing chronic total occlusions (CTO) under resource-limited conditions, highlighting the essential CTO toolbox and strategic procedural planning. It emphasizes that an antegrade-first approach, often with dual arterial access, can achieve high success in many CTO cases, illustrated through complex real-world cases from...

This session showcases best cases from the PCR Global Interventional Academy focusing on complex PCI scenarios. It addresses challenges such as managing ostial left anterior descending artery lesions, strategies for branch protection, implications of coronary involvement during TAVI, and future directions in complex coronary interventions. The...

The COVID-19 pandemic caused huge disruption to healthcare services and dramatically reduced hospital admissions for MI.1 In response, the We CARE initiative was created from a collaboration between PCR and Stent – Save a Life! to rebuild patient confidence in pursuing timely medical treatment and to help...

The aims of We CARE are to rebuild patient confidence and help stakeholders provide effective and timely cardiac care through knowledge, education and training.

Paris, France. Since the start of the COVID-19 pandemic, patients have been consistently deprived of timely cardiovascular treatment. This is due in part to measures taken in response to the sanitary crisis, but it is also due to patients' own unwillingness to seek medical help, even...

Quantitative coronary angiography-guidance versus intravascular ultrasound-guidance for drug-eluting stent implantation (GUIDE-DES trial): A multicenter, non-inferiority, randomised-controlled trial

Nicola Ryan provides her take on the final results of GUIDE-DES which were presented by Taeoh Kim during the ESC 2023 congress in Amsterdam.

Note the assumptions in this article are based on the presentation...

Nicola Ryan provides her take on the FULL REVASC trial which was presented at ACC.24 in Atlanta and published Simultaneously in NEJM.

The FULL REVASC trial is a multicentre registry-based randomised control trial comparing FFR-guided complete revascularisation of non-culprit lesions versus culprit lesion PCI alone in patients presenting...

Mirvat Alasnag provides her take on the CLEAR SYNERGY trial presented by Sanjit S Jolly at AHA 2024 in Chicago.

Nicola Ryan provides her take on the results of TAILORED-CHIP presented by Duk-Woo Park at the ESC Congress 2025 in Madrid.

Nicola Ryan provides her take on this clinical trial presented by Lisa Mielniczuk at the American College of Cardiology Scientific Session (ACC.23/WCC) – note this analysis is based upon the presented slides alone.

Chiara De Biase provides her take on the results of AQUATIC presented by Martine Gilard at ESC Congress 2025 in Madrid.

Mirvat Alasnag provides her take on OPTION-STEMI, presented by Youngkeun Ahn at ESC Congress 2025 in Madrid.

Authored by Hector Garcia-Garcia and Jorge Sanz-Sanchez, this article examines pivotal randomized clinical trials on drug-coated balloons in coronary artery disease. It highlights their role in managing in-stent restenosis, de novo small vessel lesions, and large vessel lesions while exploring future directions through ongoing trials.