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From diagnosis to device: decision-making and planning for mitral valve interventions

17 Nov 2025 – From PCR London Valves 2025

This session offers a comprehensive overview of decision-making and procedural planning for transcatheter mitral valve interventions. It emphasizes patient-specific factors, advanced imaging for valve morphology assessment, device selection, and the integration of emerging technologies to tailor optimal treatment strategies for mitral valve disease.

From diagnosis to device: decision-making and planning for mitral valve interventions

Featured research - TAVI: Predictive tools, AI innovation and reintervention strategies

17 Nov 2025 – From PCR London Valves 2025

This session presents cutting-edge research in TAVI, covering the development of predictive models for clinical valve thrombosis, comparative analyses between self-expandable and balloon-expandable valves from the Greek TAVI registry, and the emerging role of AI-guided Heart Team decisions. It also examines outcomes of reintervention strategies following...

Featured research - TAVI: Predictive tools, AI innovation and reintervention strategies

Early Career Research Award Final

17 Nov 2025 – From PCR London Valves 2025

Highlighting pioneering research in structural heart interventions, this session presents studies on the impact of transcatheter tricuspid valve replacement (TTVR) on left ventricular geometry and function, myocardial remodeling in aortic stenosis, physiological responses after mitral and tricuspid edge-to-edge repairs, advancing the understanding of device effects on...

TAVI valve-in-valve - Challenging clinical scenarios

17 Nov 2025 – From PCR London Valves 2025

This session focuses on the complexities of valve-in-valve TAVI procedures, highlighting challenging clinical scenarios such as managing severely regurgitant rapid deployment valves and degenerated stentless bioprostheses. It provides detailed insights into overcoming procedural barriers and strategies for complex valve-in-valve transcatheter aortic valve replacement (TAVR) interventions.

TAVI valve-in-valve - Challenging clinical scenarios

Learning from lived experience and contemporary evidence: shaping the treatment of women with heart valve disease

17 Nov 2025 – From PCR London Valves 2025

This session provides an in-depth exploration of the lived experiences of women with valvular heart disease, emphasizing the unique challenges in detection, diagnosis, treatment, and follow-up. It integrates contemporary evidence and the forthcoming 2025 ESC/EACTS guidelines to offer practice-ready strategies tailored to the management of valvular...

TAVI: alternative access

17 Nov 2025 – From PCR London Valves 2025

This session addresses alternative access routes for TAVI in patients with challenging vascular anatomies. It includes innovative approaches such as transapical TAV-in-TAV procedures, transcaval implantation in emergency settings, and techniques for patients with hostile iliofemoral access, showcasing adaptive strategies when conventional access is not feasible.

TAVI: challenging anatomies

17 Nov 2025 – From PCR London Valves 2025

This session explores the management of challenging anatomical conditions in TAVI procedures. Topics include strategies for difficult self-expandable valve delivery angles, addressing complications occurring during and after TAVI, and approaches for patients with severe kyphosis or complex structural abnormalities such as aneurysms and septal anomalies.

Featured research - Mitral valve interventions: Physiology & device innovation

17 Nov 2025 – From PCR London Valves 2025

This session highlights groundbreaking research on mitral valve interventions featuring advanced transcatheter techniques. Topics include coronary physiology assessment with vFFR in severe mitral regurgitation, predictive versus actual outcomes in TMVR, innovative devices like Epygon and INNOVALVE, and novel approaches such as the ReNiva posterior leaflet replacement...

Featured research - Mitral valve interventions: Physiology & device innovation

Mitral interventions in shock

17 Nov 2025 – From PCR London Valves 2025

This session highlights the intricacies of mitral valve interventions in the context of cardiogenic shock. It addresses complex cases including left-to-right shunts post septal puncture, severe ischemic mitral insufficiency with small valve anatomy, emergency mitral TEER for papillary muscle rupture, and bridging strategies to surgery.

Featured Research - TAVI: valve positioning & aortic anatomy

17 Nov 2025 – From PCR London Valves 2025

This session presents pioneering research on transcatheter aortic valve implantation (TAVI), exploring key topics such as the rise of osteogenic progenitors post-TAVI, the impact of transcatheter aortic valve planar tilt on outcomes, and the comparative results of self- versus balloon-expandable valves in patients with dilated ascending...

Featured Research - TAVI: valve positioning & aortic anatomy

Challenging mitral TEER: Barlow's disease, fibro-elastic deficiency & abnormal valve morphology

17 Nov 2025 – From PCR London Valves 2025

This session examines the feasibility and technical considerations of mitral transcatheter edge-to-edge repair (TEER) in complex anatomical and pathological scenarios. Topics include applications in Barlow's disease, fibro-elastic deficiency, congenital heart anomalies, Anderson-Fabry disease, and post-cardiac transplantation, providing valuable insights into expanding TEER indications and overcoming anatomical...

Challenging mitral TEER: Barlow's disease, fibro-elastic deficiency & abnormal valve morphology

Featured research - TAVI: Redo strategies, valve performance & access safety

17 Nov 2025 – From PCR London Valves 2025

This detailed session investigates critical aspects of TAVI procedures including the safety of selective and routine femoral access angiography post-TAVI, outcomes from the ReTAVI registry focusing on redo-TAVI in various valve frames, and a comparative analysis of JenaValve versus Evolut transcatheter heart valves in severe aortic...

Featured research - TAVI: Redo strategies, valve performance & access safety

Tricuspid valve interventions in complex scenarios - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session delves into transcatheter interventions for the tricuspid valve in complex clinical scenarios. It covers techniques for native annular reduction via TEER, management of lead-related regurgitation, challenging cases of torrential regurgitation with device detachment, and innovative methods facilitating valve-in-ring implantation, enhancing procedural efficacy in tricuspid...

TAVI in challenging annular anatomy

17 Nov 2025 – From PCR London Valves 2025

This session addresses the complexities of performing TAVI in challenging annular anatomies. It features case studies such as TAVI-in-TAVI in a patient with Morquio syndrome, strategies for managing severe annular calcification including calcium cracking techniques, and the use of large-diameter Myval valves for very large annuli...

Cardiogenic shock: transcatheter solutions

17 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter solutions for cardiogenic shock, highlighting rescue therapies such as mitral clip intervention in hypertrophic obstructive cardiomyopathy, valve-in-valve TAVI during CPR, and sequential mechanical circulatory support. It presents complex clinical cases illustrating stepwise approaches combining mechanical support and percutaneous valve repair to...

TAVI in challenging scenarios

17 Nov 2025 – From PCR London Valves 2025

This session explores complex and emergent scenarios in TAVI, featuring cases such as emergent transfemoral TAVI in failing homograft roots complicated by extensive aortic dissection, the use of BASILICA in high-risk left main occlusion terrain, and the aorto-mitral challenges during TAVR. It also covers innovative coronary...

Transcatheter mitral valve-in-valve: alternative strategy for optimal alignment

17 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter mitral valve-in-valve procedures, emphasizing alternative strategies for optimal alignment and lifetime management planning. It delves into engineering the landing zone for challenging anatomies, the integration of the LAMPOON procedure in TMVR valve-in-valve cases, and addresses complexities arising from mitral annular calcification.

Transcatheter mitral valve-in-valve: alternative strategy for optimal alignment

TAVI Valve-in-Valve: Managing unexpected anatomical challenges

17 Nov 2025 – From PCR London Valves 2025

This session examines valve-in-valve interventions in TAVI, highlighting management of concomitant left main disease, unique case narratives such as "The Highlander story," and the unpredictability inherent in these procedures. It also reviews successful transfemoral TAV-in-SAV interventions in acute heparin-induced thrombocytopenia and addresses treatment of degenerated sutureless...

TAVI Valve-in-Valve: Managing unexpected anatomical challenges

Mitral TEER and LAA closure - LIVE Case

17 Nov 2025 – From PCR London Valves 2025

Watch a LIVE case followed by a recorded case regarding a 91-year-old female with permanent AF, LAD PCI three months earlier, and recurrent GID bleeding who presented with symptomatic severe primary mitral regurgitation due to P2 prolapse and flail. CT imaging showed a LAA with a...

Mitral TEER and LAA closure -  LIVE Case

Beyond TAVI

16 Nov 2025 – From PCR London Valves 2025

This session offers a glimpse into cutting-edge structural heart interventions beyond TAVI. It introduces novel devices in early development stages targeting aortic valve stenosis and leaflet modification, discusses strategies to facilitate or defer TAVI, and provides opportunities for engagement with early-stage start-up partners innovating in structural...

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