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Unusual structural interventions: infective endocarditis, ventricular septal rupture & hypertrophic obstructive cardiomyopathy

17 Nov 2025 – From PCR London Valves 2025

This session explores unusual structural interventions, focusing on percutaneous solutions for right-sided infective endocarditis, post-myocardial infarction ventricular septal rupture closure, and novel septal reduction techniques for hypertrophic obstructive cardiomyopathy. It presents challenging cases and device selection considerations in complex structural heart disease.

Unusual structural interventions: infective endocarditis, ventricular septal rupture & hypertrophic obstructive cardiomyopathy

Featured research - TAVI - Part 13

18 Nov 2025 – From PCR London Valves 2025

This session delves into key clinical and procedural advances in TAVI, including the randomized PAF-TAVI trial assessing amiodarone for preventing post-TAVI atrial fibrillation, cost comparisons of balloon-expandable tissue preservation valves versus other devices, leaflet modification methods to reduce coronary obstruction risk, optimization techniques for valve-in-valve TAVI...

Featured research - TAVI: procedural optimization

17 Nov 2025 – From PCR London Valves 2025

Delve into comprehensive analyses of TAVI procedural outcomes and innovations in this session. Topics include the impact of intercoronary angles on coronary overlap with Evolut valves, mechanisms behind superior outcomes with the latest balloon-expandable valves, and predictive modeling of hemodynamics using physics-enhanced digital twins. Additionally, sex-specific...

Featured research - TAVI: procedural optimization

Featured research - TAVI: MELA, ViMech & more

17 Nov 2025 – From PCR London Valves 2025

This session presents cutting-edge research on Transcatheter Aortic Valve Implantation (TAVI), focusing on comparative outcomes between Myval and Evolut valves in large aortic annuli, the role of balloon post-dilation in self- and balloon-expandable valves, and novel valve-in-mechanical valve replacement approaches. Long-term follow-up data contrasting surgical aortic...

Featured research - TAVI: MELA, ViMech & more

TAVI-in-TAVI - Part 2

18 Nov 2025 – From PCR London Valves 2025

This session explores the evolving field of TAVI-in-TAVI interventions, presenting complex cases such as transfemoral TAVI-in-TAVI for degenerated transapical clip-fixed valves in transplanted hearts, management of very late TAVI migration in Bentall de Bono patients, TAVI for degenerated Evolut R valves, stepwise approaches to coronary protection...

Challenging transcatheter mitral valve replacement

17 Nov 2025 – From PCR London Valves 2025

Explore the complexities of transcatheter mitral valve replacement (TMVR) with discussions on managing mitral annular calcification, preventing paravalvular leaks in mitral valve-in-ring procedures, strategies for larger valve deployment in large mitral rings, and the evolution of transseptal TMVR providing durable relief for previously untreatable cases.

Complications of mitral TEER

18 Nov 2025 – From PCR London Valves 2025

This session addresses complications associated with mitral transcatheter edge-to-edge repair (TEER), showcasing innovative bailout methods such as snare-assisted retrieval of undeployed devices, managing leaflet perforations with latest-generation devices, cases of valve-adjacent tears, mechanical support considerations when pumps fail, and the clinical impact of iatrogenic fossa ovalis...

Complications of paravalvular leak closure

18 Nov 2025 – From PCR London Valves 2025

This session addresses the complexities and risks associated with paravalvular leak (PVL) closure. It offers detailed analysis of principal complications, prevention techniques, and practical management strategies shared by experienced operators. Case studies illustrate complications such as device embolisation, prosthetic valve disc impingement, and delivery failures, along...

TAVI complications - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session explores complex and uncommon complications associated with TAVI procedures, highlighting challenging clinical scenarios such as neurological complications in bicuspid valves, management of critically unstable left ventricles, and outcomes in complex valve interventions. Each topic offers valuable lessons for improving procedural safety and patient outcomes...

Getting to the heart of access: mastering femoral puncture and vascular closure

18 Nov 2025 – From PCR London Valves 2025

This session provides an in-depth understanding of femoral anatomy and the critical role of imaging in ensuring safe vascular access via femoral puncture. It covers the latest equipment used for vascular access and closure, highlighting haemostasis techniques and closure devices. Interactive case scenarios offer practical insights...

Thrombotic complications of transcatheter valves

17 Nov 2025 – From PCR London Valves 2025

Focusing on thrombotic complications following transcatheter valve implantation, this session presents a series of complex cases illustrating acute and late thrombotic events, their clinical presentations, and the pivotal role of multimodality imaging in diagnosis and management. Insights include coronary embolism and cardiogenic shock scenarios, emphasizing challenges...

TAVI embolisation - Part 1

18 Nov 2025 – From PCR London Valves 2025

This session explores the critical issue of TAVI valve embolisation, presenting real-world cases that emphasize rapid problem-solving and interventional management strategies. Discussions include bailout techniques for embolised valves, managing multiple valve implantations in severe aortic stenosis, and expectations for TAVI in pure aortic regurgitation. The session...

Multiple valve interventions

17 Nov 2025 – From PCR London Valves 2025

This session delves into the complexities of multiple valve interventions, showcasing a fully transcatheter strategy for combined complex heart procedures. It presents stepwise approaches for managing multivalvular disease with severe pulmonary hypertension and sequential transcatheter strategies when single valve treatment is insufficient. Additional focus is given...

Transcatheter tricuspid valve replacement - LIVE Case

18 Nov 2025 – From PCR London Valves 2025

Live case: An 86-year-old male, with a history of PPM, permanent AF, CKD stage 3, and moderately impaired LV function (50–55%), presented with symptomatic torrential mixed TR (tricuspid annular dilatation and pacing lead on the septal leaflet). An Evoque valve was implanted under fluoroscopy and TEE...

Transcatheter tricuspid valve replacement - LIVE Case

Featured research: imaging innovation and device performance in TAVI

18 Nov 2025 – From PCR London Valves 2025

This session presents featured research on TAVI, highlighting long-term outcomes and innovations in transcatheter aortic valve therapy. It includes registry data on mild paravalvular leak impact, five-year evaluations of the Hydra THV, comparisons between deep learning and manual echocardiographic assessments, pacemaker implantation outcomes post-TAVI, and procedural...

Featured research: imaging innovation and device performance in TAVI

Complications of valve-in-valve TAVI

18 Nov 2025 – From PCR London Valves 2025

This session addresses the complex complications associated with valve-in-valve TAVI procedures. Topics include delayed coronary compromise, unexpected clinical scenarios, the importance of recognizing surgical bioprosthesis types, the dual role of calcium in TAVI, and intricate left ventricular complications that can arise post valve-in-valve interventions.

Challenging mitral interventions

18 Nov 2025 – From PCR London Valves 2025

This session explores the complexities of mitral interventions, highlighting advancements and challenges in transcatheter mitral valve repair (TMVR). Topics include the benefits of a simplified single-step TMVR approach, the influence of hemodynamic parameters on MitraClip therapy outcomes, strategies for managing persistent pulmonary oedema, and approaches to...

TAVI: alternative access - Part 2

18 Nov 2025 – From PCR London Valves 2025

This session addresses alternative access routes for TAVI in patients with challenging vascular anatomy. Topics include transapical valve-in-valve procedures complicated by severe aortic regurgitation, percutaneous TAVI via the brachiocephalic trunk, and strategies for managing hostile vascular anatomies. Solutions for scenarios where transfemoral TAVI is not feasible...

Featured research - Tricuspid valve (Part 1)

24 Nov 2024 – From PCR London Valves 2024

Explore the latest research on tricuspid valve interventions in this featured session from PCR London Valves 2024. Discover insights on the prognostic impact of heart failure hospitalization in severe tricuspid regurgitation, the influence of moderate mitral regurgitation in tricuspid TEER patients, the association of effective right...

Featured research - Tricuspid valve (Part 1)

Featured cases - TAVI coronary complications

24 Nov 2024 – From PCR London Valves 2024

Delve into this session featuring selected PCR London Valves 2024 Clinical Cases submissions on TAVI coronary complications. Explore a case of post-TAVR acute pulmonary edema, an unusual inter-TAVI diastolic gradient, late coronary artery occlusion after TAVR-in-SAVR, acute coronary syndrome after TAVI due to subacute left main...

Featured cases - TAVI coronary complications
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