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The top ten impactful papers from 2025 on tricuspid intervention we almost missed

13 Jan 2026

Transcatheter interventions have rapidly reshaped the management of tricuspid valve disease, with landmark trials establishing feasibility and early clinical benefit.

Beyond these pivotal studies, a series of less visible but highly informative papers addressed mechanisms, complications, patient phenotypes, and unintended consequences of intervention.

This curated selection highlights ten impactful tricuspid...

Alessandro Sticchi

Author

Alessandro Sticchi
The top ten impactful papers on tricuspid intervention we almost missed

Transcatheter aortic valve implantation without routine percutaneous coronary intervention: A randomized controlled trial (PRO-TAVI Trial)

29 Mar 2026

Jonathan Curio provides his take on the PRO-TAVI trial presented by Michiel Voskuil at ACC.26 in New Orleans and simultaneously published in The Lancet.

Jonathan Curio

Author

Jonathan Curio
TAVI without routine PCI: PRO-TAVI randomized controlled trial

A randomized, placebo-controlled trial of chronic total occlusion PCI in stable angina - ORBITA-CTO trial

03 Apr 2026

Kalaivani Mahadevan provides an in-depth analysis of the ORBITA-CTO trial: a first-ever randomised, double-blind, placebo-controlled trial evaluating CTO PCI in stable angina patients.
She also interviewed principal investigators Sarosh Khan and John Davies following the LBCT Scientific Session at ACC.26 in New Orleans and simultaneous publication in...

John Davies

Author

John Davies
Kalaivani Mahadevan

Author

Kalaivani Mahadevan
Sarosh Khan

Author

Sarosh Khan
ORBITA-CTO: Chronic total occlusion PCI in stable angina

Intravascular ultrasound-guided or angiography-guided complex high-risk PCI – The IVUS CHIP trial

28 Mar 2026

Daniele Giacoppo reports and provides his perspective on the main results of the IVUS-CHIP trial, presented by Roberto Diletti from the Erasmus University Medical Center, Rotterdam, the Netherlands, during a Late-Breaking Trials session at the ACC.26 in New Orleans, and simultaneously published in the New England Journal of...

Daniele Giacoppo

Author

Daniele Giacoppo
Intravascular ultrasound guidance for complex high-risk indicated procedures – The Ivus Chip trial
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