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Featured research - TAVI: procedural optimization

17 Nov 2025 – From PCR London Valves 2025

Delve into comprehensive analyses of TAVI procedural outcomes and innovations in this session. Topics include the impact of intercoronary angles on coronary overlap with Evolut valves, mechanisms behind superior outcomes with the latest balloon-expandable valves, and predictive modeling of hemodynamics using physics-enhanced digital twins. Additionally, sex-specific...

Featured research - TAVI: procedural optimization

TAVI: high coronary risk - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session addresses the challenges and solutions related to high coronary risk in TAVI procedures. Topics include advanced coronary protection strategies, innovative approaches to complex valve-in-valve interventions, the benefits of balloon-assisted techniques, management of right coronary cusp obstruction through UNICORN technology, and prevention of sinus sequestration...

TAVI: complex vascular access - Part 2

17 Nov 2025 – From PCR London Valves 2025

Focus on complex vascular access challenges in TAVI with this session covering strategies such as the pave and crack technique for inaccessible vessels, management of bicuspid aortic stenosis with hostile access and horizontal aorta, complex single transfemoral access procedures, and combined interventions including left atrial appendage...

Paravalvular leaks and VSD percutaneous closure - Recorded cases

17 Nov 2025 – From PCR London Valves 2025

Recorded case 1: A 56-year-old female with a prior mechanical mitral valve replacement (Star GK, 2018), permanent AF, and normal LV function presented with recurrent HF admissions due to paravalvular leaks. She was treated with implantation of multiple plugs via a transseptal approach using a Destination...

Paravalvular leaks and VSD percutaneous closure - Recorded cases

Tricuspid valve interventions in complex scenarios - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session delves into transcatheter interventions for the tricuspid valve in complex clinical scenarios. It covers techniques for native annular reduction via TEER, management of lead-related regurgitation, challenging cases of torrential regurgitation with device detachment, and innovative methods facilitating valve-in-ring implantation, enhancing procedural efficacy in tricuspid...

Cardiogenic shock: transcatheter solutions

17 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter solutions for cardiogenic shock, highlighting rescue therapies such as mitral clip intervention in hypertrophic obstructive cardiomyopathy, valve-in-valve TAVI during CPR, and sequential mechanical circulatory support. It presents complex clinical cases illustrating stepwise approaches combining mechanical support and percutaneous valve repair to...

Leaflet modification techniques: latest acronyms, concepts and best practice

17 Nov 2025 – From PCR London Valves 2025

Gain comprehensive insights into leaflet modification techniques with a focus on the latest acronyms, concepts, and best practices. This session covers step-by-step approaches to transcatheter electrosurgical leaflet modification, including BASILICA, SHORTCUT, and UNICORN, alongside troubleshooting strategies and the innovative SURPLUS surgical technique.

Leaflet modification techniques: latest acronyms, concepts and best practice

Cool AMI EU pivotal trial- final results after trial discontinuation following ad interim analysis

18 May 2021

Results of the interim analyses performed after 12 months in the first 111 patients enrolled in phase II Cool AMI trial evaluating safety and effectiveness of systemic therapeutic hypothermia as an adjunctive therapy in anterior STEMI undergoing PCI as compared to PCI only. Analyses showed significant...

Cool AMI EU pivotal trial- final results after trial discontinuation following ad interim analysis

Post-TAVI cardiac arrest associated to acute coronary occlusion: facing the storm to gain calm

26 Jan 2024

Observe this TAVI case featuring pulseless electrical activity due to an unforeseen acute occlusion of the right coronary artery, and discover the strategies employed to address and resolve this critical complication.

Authors :

Juan Guzmán Olea, Gonzalo Tolosa Dzul, Beatriz Villegas González, Jonathan Uribe González,  Guillermo Arenas Fonseca, Tomás Herrera Arzola, Rosa Gutiérrez Castañeda, Víctor Sustaita Cerda, Raúl Cruz Palomera, Arely Méndez Mercado, Darío Valencia González, Carlos Javier González Álvarez, Héctor Hugo Escutia Cuevas, Daniel Iván Pérez Vásquez, Gabriel Guzmán Olea.Specialty Hospital, Puebla, IMSS, México
Post-TAVI cardiac arrest associated to acute coronary occlusion: facing the storm to gain calm

Transcatheter aortic valve replacement in small aortic annuli: Results from the FRANCE-TAVI registry

17 Sep 2022

Mirvat Alasnag provides her take on the outcomes of small annuli sub-study from the FRANCE-TAVI Registry which included 1,195 patients. This trial was presented by Walid Ben-Ali at TCT 2022.

Dr. Mirvat Alasnag

Author

Mirvat Alasnag
Transcatheter aortic valve replacement in small aortic annuli: Results from the FRANCE-TAVI registry

Transcatheter vs surgical aortic valve replacement in aortic stenosis patients at low surgical risk: 3-year outcomes from the Evolut Low Risk trial

05 Mar 2023

Luigi Biasco provides his take on the clinical trial presented by John K. Forrest from Yale University School of Medicine, New Haven, Connecticut, USA during the 2023 ACC/WCC annual congress held in New Orleans, Louisiana.

Luigi Biasco

Author

Luigi Biasco
Transcatheter versus surgical aortic valve replacement in aortic stenosis patients at low surgical risk: 3-year outcomes from the Evolut low risk Trial

Harmonising optimal strategy for treatment of coronary artery diseases – bleeding risk: HOST-BR

29 Mar 2025

Daniele Giacoppo and Nicola Ammirabile provide their take on the main results of the HOST-BR trial, presented by Hyo-Soo Kim at ACC.25 in Chicago.

Nicola Ammirabile

Author

Nicola Ammirabile
Daniele Giacoppo

Author

Daniele Giacoppo
Harmonising optimal strategy for treatment of coronary artery diseases – bleeding risk: HOST-BR

When transfemoral TAVI is not an option: rethinking alternative access strategies

18 Jun 2026

In this article, Ulrich Schäfer explores the evolving landscape of access strategies in transcatheter aortic valve implantation (TAVI). While the transfemoral approach remains the gold standard, a significant proportion of patients are not suitable due to peripheral vascular disease or anatomical constraints.
Drawing on clinical evidence and...

Author

Ulrich Schaefer
Alternative access, if transfemoral is not working
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