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Featured research - Mitral valve interventions - Part 4

18 Nov 2025 – From PCR London Valves 2025

This research-focused session presents contemporary evidence and clinical outcomes related to mitral valve interventions. It includes data on transapical mitral valve-in-ring implantation from the European Tendyne registry, prognostic utility of CT-derived fatty muscle fraction in mitral TEER, and comparative outcomes between transapical TMVR and mitral TEER....

Paravalvular leak closure - Part 3

18 Nov 2025 – From PCR London Valves 2025

This session addresses the complexities of paravalvular leak closure, emphasizing resilience in procedural approaches. It covers sizing balloon techniques that enhance treatment efficacy in aortic paravalvular leaks and explores closure strategies following Ozaki procedures. Management of mitral paravalvular leaks in high-risk patients and innovative solutions for...

TAVI complications - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session explores complex and uncommon complications associated with TAVI procedures, highlighting challenging clinical scenarios such as neurological complications in bicuspid valves, management of critically unstable left ventricles, and outcomes in complex valve interventions. Each topic offers valuable lessons for improving procedural safety and patient outcomes...

Featured research - TAVI - Part 14

18 Nov 2025 – From PCR London Valves 2025

This featured research session presents pivotal findings on transcatheter aortic valve implantation (TAVI), including 30-day and one-year outcomes from the VANTAGE trial, novel concepts for assessing aortic stenosis severity, and the influence of mitral annular calcification on conduction disturbances. Additional topics cover the role of clinical...

TAVI in challenging anatomies

18 Nov 2025 – From PCR London Valves 2025

This session focuses on the challenges of performing TAVI in complex anatomical settings. It covers issues such as valve compression, hypertrophic cardiomyopathy-related left ventricular responses, alternative management strategies during crises, and handling anatomical complexities like membranous septal aneurysm at the annulus and sinus of Valsalva in...

DK Crush like you’ve never seen it before

  • Multi-modality simulation to unveil the hidden parts & small obstacles that can result in complications
  • Angioscopy directly inside the coronary artery to provide a better understanding of 3D stent configuration

Commented by Goran Stankovic and William Wijns

Part 1 of a 3-part series.
Next episode: How to correct incomplete crush and...

DK Crush like you’ve never seen it before

How to correct incomplete crush and how to prevent lack of carina coverage

  • Differentiating between complete and incomplete crush
  • The importance of sequential crush and bigger balloons, adequately sized according to proximal vessel diameter

Commented by Goran Stankovic and William Wijns

Part 2 of a 3-part series:  
Previous episode: DK Crush like you’ve never seen it before
Coming up next: Main vessel stenting in DK-Crush, lessons...

How to correct incomplete crush and how to prevent lack of carina coverage

Main vessel stenting in DK-Crush: lessons from stepwise provisional strategy

  • Optimisation of side branch stenting
  • How to optimally deploy the second stent

Commented by Goran Stankovic and William Wijns

Part 3 of a 3-part series. Previous episode: How to correct incomplete crush and how to prevent lack of carina coverage

Main vessel stenting in DK-Crush: lessons from stepwise provisional strategy

Siemens Healthineers introduces industry-first seamlessly integrated end-to-end solution for CT-guided percutaneous coronary interventions

19 May 2026

OPTIMUM: Outcomes of Percutaneous RevascularizaTIon for Management of SUrgically Ineligible Patients with Multivessel or Left Main Coronary Artery Disease

04 Nov 2021

Mirvat Alasnag reviews the OPTIMUM trial, presented by David E. Kandzari, which reports outcomes in a subset of patients who are increasingly seen in modern day catheterization laboratories. It is noteworthy that 1 in 5 patients with left main or multivessel disease are considered surgically ineligible.

Dr. Mirvat Alasnag

Author

Mirvat Alasnag
OPTIMUM: Early Outcomes From a Prospective Registry of PCI in Patients at Prohibitive Risk for CABG

First-in-human experience with EasyCross: a novel catheter for a safe and correct aortic valve crossing

14 Jun 2024

This EIJ image highlights a new device designed to enhance the safety and efficiency of ViV TAVI procedures, particularly TAV-in-TAV, by reducing attempts to cross the valve and preventing guidewire misnavigation, thereby minimizing complications and procedure time.

First-in-human experience with EasyCross: a novel catheter for a safe and correct aortic valve crossing

Rapid CT-guided emergency TAVI-in-TAVI-in-valve for cardiogenic shock with high coronary obstruction risk

14 Apr 2026

An 85-year-old man presented in cardiogenic shock with torrential aortic regurgitation after prior surgical and TAVI valve-in-valve procedures. With high coronary obstruction risk, urgent CT assessment and in-silico simulations guided a rapid redo TAVI-in-TAVI-in-valve implantation, demonstrating that CT-assisted emergency redo-TAVI is feasible and lifesaving in high-risk...

Rapid CT-guided emergency TAVI-in-TAVI-in-valve for cardiogenic shock with high coronary obstruction risk

UNIVERSAL: routine ultrasonography guidance for femoral vascular access for cardiac procedures - A randomized clinical Trial

19 Sep 2022

Ali Nazmi Calik provides his take on UNIVERSAL randomized clinical trial, which questioned whether routine ultrasonography guidance for CFA access for cardiac procedures reduces bleeding or vascular complications. This trial was presented by Sanjit S. Jolly during TCT 2022.

Author

Ali Nazmi Calik
UNIVERSAL: routine ultrasonography guidance for femoral vascular access for cardiac procedures - A randomized clinical Trial
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