80 results

Dapagliflozin in acute myocardial infarction: Cardiometabolic benefits without impact on cardiovascular death or heart failure hospitalization: The jury is still out

14 Nov 2023

Luis Ortega Paz provides his take on DAPA-MI - A registry-based randomized trial of dapagliflozin in patient with acute myocardial infarction without diabetes, which was presented by Stefan James at AHA 2023 in Philadelphia.

Author

Luis Ortega-Paz

Distal radial approach to reaccess and recanalize the occluded radial artery

30 Apr 2021

A 56-year-old man was re-admitted with chest pain. He had been hospitalized 2 weeks before because of MI, was suffering from metastatic carcinoma with recurrent PTE, and was on long-term subcutaneous heparin...

THEMIS - Main results of the effect of Ticagrelor on health outcomes in diabetes mellitus patients intervention study

03 Sep 2019

Author

Giuseppe Di Gioia

Author

Pierre Sabouret

PCR Rio Valves 2025: Discover what’s in store for this new initiative

Whether you're passionate about structural heart interventions or looking to enhance your echocardiography skills, PCR Rio Valves is the place to be. Take a look at the programme highlights ✨

The PASCAL IID Registry: A prospective registry for transcatheter edge-to-edge repair in prohibitive risk patients with degenerative mitral regurgitation and complex mitral valve anatomy

17 Sep 2022

Alex Sticchi provides his take on the PASCAL IID Registry and an initial comparison with the CLASP IID. The trial was presented by Jörg Hausleiter during TCT Congress 2022.

Author

Alessandro Sticchi

One-year results from the FUTURE-II trial

18 May 2021

A decade already passed from the first use of bioresorbable vascular scaffold in percutaneous coronary interventions. The first studies - by using surrogate endpoints - showed some superiority of BRS vs. metallic drug-eluting stent in terms of the so-called vascular restoration therapy with recovery of vasomotion...

Interventional closure of LVOT to LA shunt after aortic valve replacement

30 Jun 2023

Watch the case of a 79-year-old male patient admitted to hospital with progressive dyspnea in NYHA functional class III-IV and signs of fluid overload, who presented a subannular perforation of LVOT in the region of fibrous aortomitral continuity, and find out how he was treated.

TAVI: a fascinating 20-year-long odyssey with a happy ending

10 Nov 2017

This new "disruptive" technology is among the most important medical breakthroughs to date. TAVI emerged in 2002 to profoundly alter the landscape of cardiovascular medicine.

SPYRAL HTN-OFF MED Pivotal: Efficacy of Catheter-Based Renal Denervation in the Absence of Antihypertensive Medications

04 Apr 2020

The SPYRAL HTN-OFF MED Pivotal trial is a sham controlled randomized study examining the efficacy and safety of renal artery denervation (RDN) compared to a sham group, and the primary endpoint was the reduction in the blood pressure of subjects with uncontrolled hypertension not on antihypertensive...

Author

Mirvat Alasnag

SHARE (Sustain Health Development in Africa)

30 Mar 2017

SHARE is turning its attention to Mali in West Africa with a view to duplicating the Mauritanian experience. Find our more about how this NGO helps to save lives!

Hybrid step-by-step approach to perform a Robotic DK Crush PCI

28 Jan 2022

View the case of this 65-year-old male patient who was staged for R-PCI of a Medina 1,1,1 distal left main lesion, and discover how the authors used a hybrid robotic and manual approach to perform a DK crush procedure using the second-generation R-PCI device.

PACMAN AMI: Effects of Alirocumab on Coronary Atherosclerosis Assessed by Serial Multimodality Intracoronary Imaging in Patients With Acute Myocardial Infarction

03 Apr 2022

Nicola Ryan provides a PICOT analysis of PACMAN AMI: a double-blind, placebo-controlled, randomized trial presented at ACC 2022 and simultaneously published in JAMA.

Author

Nicola Ryan

FDA approves LimFlow system in patients with chronic limb-threatening ischemia and no suitable endovascular or surgical revascularization options

15 Sep 2023

Landmark New England Journal of Medicine publication reports positive results from PROMISE II pivotal trial showing that LimFlow system saves most patients with end-stage peripheral artery disease from major amputation

30 Mar 2023

RESHAPE-HF2 - Percutaneous repair of moderate-to-severe or severe functional mitral regurgitation in patients with symptomatic heart failure

01 Sep 2024

Nicola Ryan provides her take on the RESHAPE-HF2 trial presented by Stefan Anker at the ESC Congress 2024 in London and simultaneously published in the NEJM.

The RESHAPE-HF 2 trial is a prospective randomised control trial comparing transcatheter mitral valve repair (TEER) and guideline-directed medical therapy to guideline-directed medical...

Author

Nicola Ryan

SENIOR-RITA - Older patients with non-ST segment elevation myocardial infarction randomised interventional treatment trial

02 Sep 2024

Mirvat Alasnag provides her take on the SENIOR-RITA trial, presented by Vijay Kunadian at the ESC Congress 2024 in London.

Author

Mirvat Alasnag

3-year Efficacy Outcomes From the Spyral Htn-on Med Pilot Study: Long Term Effect of Renal Denervation On Blood Pressure Reduction in Patients on Antihypertension Medications

22 Mar 2022

Ali Nazmi Calik provides his take on the long-term results of the SPYRAL HTN-ON MED trial which demonstrated the durable efficacy and safety of RDN in patients who are already on one to three antihypertensive drugs.

Author

Ali Nazmi Calik

A review of the 2024 ESC Guidelines on elevated blood pressure and hypertension

13 Nov 2024

Lucas Lauder and Felix Mahfoud provide a summary of the ESC Guidelines on elevated blood pressure and hypertension presented by John William McEvoy and Rhian Touyz at ESC Congress 2024 in London.

Author

Lucas Lauder

Author

Felix Mahfoud

Intravascular ultrasound-guided versus angiography-guided percutaneous coronary intervention in acute coronary syndromes: The multicenter, randomized, blinded, IVUS-ACS Trial

09 Apr 2024

Marco Spagnolo and Daniele Giacoppo report the main results of the IVUS-ACS trial presented by Shao-Liang Chen, from the Nanjing First Hospital, Nanjing Medical University, Nanjing, in a Featured Clinical Research session at ACC.24 in Atlanta and simultaneously published in The Lancet.(1)

Author

Daniele Giacoppo

Author

Marco Spagnolo

NEO-MINDSET: Early withdrawal of aspirin after percutaneous coronary intervention for acute coronary syndrome

02 Sep 2025

Daniele Giacoppo reports and provides his perspective on the main results of the ambitious NEOMINDSET trial, presented by Pedro Lemos from the Hospital Israelita Albert Einstein, São Paulo, Brazil, during a Late Breaking Trials session at the ESC Congress 2025 in Madrid, and simultaneously published in the New...

Author

Daniele Giacoppo