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Challenging TAVI

16 Nov 2025 – From PCR London Valves 2025

This session addresses the complexities encountered in transcatheter aortic valve implantation (TAVI) in challenging anatomical settings. It reviews management of bicuspid valves with calcification, horizontal aorta, coronary artery anomalies, and navigation of difficult angles. Case studies illustrate techniques to optimize commissural alignment and strategies to address...

Featured research - Mitral valve interventions: Physiology & device innovation

17 Nov 2025 – From PCR London Valves 2025

This session highlights groundbreaking research on mitral valve interventions featuring advanced transcatheter techniques. Topics include coronary physiology assessment with vFFR in severe mitral regurgitation, predictive versus actual outcomes in TMVR, innovative devices like Epygon and INNOVALVE, and novel approaches such as the ReNiva posterior leaflet replacement...

Featured research - Mitral valve interventions: Physiology & device innovation

Featured research - Tricuspid valve intervention: the TRIPLACE registry

17 Nov 2025 – From PCR London Valves 2025

This session features cutting-edge research on tricuspid valve interventions, including insights from the TRIPLACE registry on orthotopic TTVR thrombosis, predictive value of three-dimensional tricuspid annulus measurements for procedural outcomes, early clinical experiences with novel TTVR systems, and procedural clipping strategies based on results from the BRIGHT...

Featured research - Tricuspid valve intervention: the TRIPLACE registry

Featured research - TAVI: Predictive tools, AI innovation and reintervention strategies

17 Nov 2025 – From PCR London Valves 2025

This session presents cutting-edge research in TAVI, covering the development of predictive models for clinical valve thrombosis, comparative analyses between self-expandable and balloon-expandable valves from the Greek TAVI registry, and the emerging role of AI-guided Heart Team decisions. It also examines outcomes of reintervention strategies following...

Featured research - TAVI: Predictive tools, AI innovation and reintervention strategies

Left atrial appendage occlusion

17 Nov 2025 – From PCR London Valves 2025

This session focuses on the complexities and innovations in left atrial appendage occlusion (LAAO) procedures. It covers transesophageal ICE monitoring, challenges posed by existing atrial septal occluders, combined surgical and percutaneous approaches, and the practical experience with the Ultraseal device. These insights advance understanding of procedural...

Mitral TEER and LAA closure - LIVE Case

17 Nov 2025 – From PCR London Valves 2025

Watch a LIVE case followed by a recorded case regarding a 91-year-old female with permanent AF, LAD PCI three months earlier, and recurrent GID bleeding who presented with symptomatic severe primary mitral regurgitation due to P2 prolapse and flail. CT imaging showed a LAA with a...

Mitral TEER and LAA closure -  LIVE Case

TAVI in patients with concomitant valve and coronary artery disease

17 Nov 2025 – From PCR London Valves 2025

Focused on patients with concomitant valve and coronary artery disease, this session examines evaluation strategies for aortic stenosis burden, integrates recent trial data on combined TAVI and PCI, and discusses optimal management approaches in complex multi-valve disease scenarios through detailed case presentations and clinical outcomes.

TAVI in patients with concomitant valve and coronary artery disease

TAVI in challenging scenarios

17 Nov 2025 – From PCR London Valves 2025

This session explores complex and emergent scenarios in TAVI, featuring cases such as emergent transfemoral TAVI in failing homograft roots complicated by extensive aortic dissection, the use of BASILICA in high-risk left main occlusion terrain, and the aorto-mitral challenges during TAVR. It also covers innovative coronary...

Transcatheter mitral valve-in-valve: alternative strategy for optimal alignment

17 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter mitral valve-in-valve procedures, emphasizing alternative strategies for optimal alignment and lifetime management planning. It delves into engineering the landing zone for challenging anatomies, the integration of the LAMPOON procedure in TMVR valve-in-valve cases, and addresses complexities arising from mitral annular calcification.

Transcatheter mitral valve-in-valve: alternative strategy for optimal alignment

Unusual structural interventions: infective endocarditis, ventricular septal rupture & hypertrophic obstructive cardiomyopathy

17 Nov 2025 – From PCR London Valves 2025

This session explores unusual structural interventions, focusing on percutaneous solutions for right-sided infective endocarditis, post-myocardial infarction ventricular septal rupture closure, and novel septal reduction techniques for hypertrophic obstructive cardiomyopathy. It presents challenging cases and device selection considerations in complex structural heart disease.

Unusual structural interventions: infective endocarditis, ventricular septal rupture & hypertrophic obstructive cardiomyopathy

Valve interventions in grown-up congenital heart disease

17 Nov 2025 – From PCR London Valves 2025

This session presents complex valve interventions in patients with grown-up congenital heart disease, showcasing innovative transcatheter approaches including combined TAVI and pulmonary valve implantation in high-risk patients. Cases highlight management strategies in elderly patients with concomitant conditions such as patent ductus arteriosus and severe left ventricular...

Featured research - TAVI: cutting-edge developments

17 Nov 2025 – From PCR London Valves 2025

This featured research session reviews cutting-edge developments in TAVI, addressing challenges and outcomes in young patients with bicuspid aortic valve stenosis, prognostic significance of concomitant valvular disease, and long-term results of prophylactic chimney stenting and prosthetic valve performance in bicuspid stenosis.

Featured research - TAVI: cutting-edge developments

TAVI and coronary artery disease

16 Nov 2025 – From PCR London Valves 2025

This session focuses on the interplay between TAVI and coronary artery disease, discussing high-risk TAVR cases requiring complex left main PCI with prophylactic ECMO support. It provides guidance on timing and strategies for managing concomitant coronary artery disease in TAVI patients, addressing the critical decision-making process...

When the first TAVI fails: no panic, just planning

19 Jan 2026

An 81-year-old man with history of severe aortic stenosis previously treated with a balloon-expandable transcatheter valve was referred for progressive exertional dyspnea due to bioprosthetic valve degeneration.

How would you treat this patient?

Barbara Bellini

Author

Barbara Bellini
When the first TAVI fails: no panic, just planning

TAVI: vascular complications

16 Nov 2025 – From PCR London Valves 2025

This session examines vascular complications associated with transfemoral TAVI procedures, featuring challenging cases such as initial procedural obstacles, complex post-TAVI vascular events, and unusual complications. It also explores advanced techniques like intravascular lithotripsy to optimize TAVI outcomes in patients with severe calcific iliofemoral disease.

Spotlight on a selection of top Late-breaking Trials presented at PCR London Valves 2025

17 Nov 2025

View a snapshot of the results of these 4 trials in valvular and structural interventions presented in London during this year's Heart Team Course!

Selection of top Late-breaking Trials presented at #PCRLV

Validation of intravascular ultrasound-defined optimal stent expansion criteria for favorable 1-year clinical outcomes

17 Nov 2025

This individual patient data analysis of the three largest RCTs evaluating IVUS-guided stent optimisation showed that an MSA > 5.5 mm2 was associated with reduced TVF at one year. 

Ruxandra Sava

Reviewer

Ruxandra Sava
Nicola Ryan

Reviewer

Nicola Ryan
Validation of IVUS-defined optimal stent expansion criteria for favorable 1-year clinical outcomes

PCR: Collaborative, inclusive and global

15 Nov 2025 – From PCR London Valves 2025

At PCR, collaboration and inclusion are at the heart of everything we do.

Together, we create an environment where expertise is shared, talents complement each other, and diversity becomes a strength. It is this collective spirit that drives interventional cardiology forward and inspires innovation every day.

During PCR London...

PCR: Collaborative, inclusive and global

TAVI: high coronary risk - Part 2

16 Nov 2025 – From PCR London Valves 2025

This session presents advanced strategies to mitigate high coronary risk during valve-in-valve TAVR procedures, including the LLAMACORN technique and chimney stenting to prevent coronary obstruction. It discusses management of misaligned prostheses, complex aortic and coronary anatomies, and innovative approaches such as stent crush techniques to ensure...

Complex mitral and tricuspid TEER

16 Nov 2025 – From PCR London Valves 2025

This session highlights complex cases in mitral and tricuspid transcatheter edge-to-edge repair (TEER), addressing challenges such as septal obstacles in patients with old atrial septal occluders, management of residual atrial septal defects post-mitral valve-in-ring replacement, and innovative multidisciplinary approaches. It also covers hybrid transapical mitral valve-in-valve...

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