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Featured research - Mitral valve interventions: Physiology & device innovation

17 Nov 2025 – From PCR London Valves 2025

This session highlights groundbreaking research on mitral valve interventions featuring advanced transcatheter techniques. Topics include coronary physiology assessment with vFFR in severe mitral regurgitation, predictive versus actual outcomes in TMVR, innovative devices like Epygon and INNOVALVE, and novel approaches such as the ReNiva posterior leaflet replacement...

Featured research - Mitral valve interventions: Physiology & device innovation

Left atrial appendage occlusion

17 Nov 2025 – From PCR London Valves 2025

This session focuses on the complexities and innovations in left atrial appendage occlusion (LAAO) procedures. It covers transesophageal ICE monitoring, challenges posed by existing atrial septal occluders, combined surgical and percutaneous approaches, and the practical experience with the Ultraseal device. These insights advance understanding of procedural...

TAVI: complex vascular access

17 Nov 2025 – From PCR London Valves 2025

This session addresses the challenges of complex vascular access in transcatheter aortic valve implantation (TAVI). It discusses strategies for navigating difficult thoraco-abdominal aortic anatomies, managing double aortic arches, and overcoming hostile femoral access. Case studies illustrate meticulous planning and innovative solutions essential for successful TAVI in...

TAVI: nightmare in the cathlab - Annular perforation, coronary obstruction & balloon rupture

17 Nov 2025 – From PCR London Valves 2025

This session presents critical case analyses of complicated TAVI procedures, highlighting unexpected and severe intra-procedural events such as annular perforation, leaflet modification complications, coronary obstructions, and device failures. It emphasizes prevention strategies, bailout techniques, and acute management to prepare clinicians for handling TAVI-related emergencies effectively.

TAVI: nightmare in the cathlab - Annular perforation, coronary obstruction & balloon rupture

Challenging mitral TEER: Barlow's disease, fibro-elastic deficiency & abnormal valve morphology

17 Nov 2025 – From PCR London Valves 2025

This session examines the feasibility and technical considerations of mitral transcatheter edge-to-edge repair (TEER) in complex anatomical and pathological scenarios. Topics include applications in Barlow's disease, fibro-elastic deficiency, congenital heart anomalies, Anderson-Fabry disease, and post-cardiac transplantation, providing valuable insights into expanding TEER indications and overcoming anatomical...

Challenging mitral TEER: Barlow's disease, fibro-elastic deficiency & abnormal valve morphology

Tricuspid valve interventions in complex scenarios - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session delves into transcatheter interventions for the tricuspid valve in complex clinical scenarios. It covers techniques for native annular reduction via TEER, management of lead-related regurgitation, challenging cases of torrential regurgitation with device detachment, and innovative methods facilitating valve-in-ring implantation, enhancing procedural efficacy in tricuspid...

Cardiogenic shock: transcatheter solutions

17 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter solutions for cardiogenic shock, highlighting rescue therapies such as mitral clip intervention in hypertrophic obstructive cardiomyopathy, valve-in-valve TAVI during CPR, and sequential mechanical circulatory support. It presents complex clinical cases illustrating stepwise approaches combining mechanical support and percutaneous valve repair to...

Interventions in shock

17 Nov 2025 – From PCR London Valves 2025

This session addresses critical interventions in cardiogenic shock, highlighting innovative approaches such as combined valve procedures, management of acute functional mitral regurgitation in STEMI, and advanced transcatheter edge-to-edge repair techniques in refractory heart failure. It offers a comprehensive exploration of strategies to navigate complex hemodynamic instability...

Unusual structural interventions: infective endocarditis, ventricular septal rupture & hypertrophic obstructive cardiomyopathy

17 Nov 2025 – From PCR London Valves 2025

This session explores unusual structural interventions, focusing on percutaneous solutions for right-sided infective endocarditis, post-myocardial infarction ventricular septal rupture closure, and novel septal reduction techniques for hypertrophic obstructive cardiomyopathy. It presents challenging cases and device selection considerations in complex structural heart disease.

Unusual structural interventions: infective endocarditis, ventricular septal rupture & hypertrophic obstructive cardiomyopathy

Thrombotic complications of transcatheter valves

17 Nov 2025 – From PCR London Valves 2025

Focusing on thrombotic complications following transcatheter valve implantation, this session presents a series of complex cases illustrating acute and late thrombotic events, their clinical presentations, and the pivotal role of multimodality imaging in diagnosis and management. Insights include coronary embolism and cardiogenic shock scenarios, emphasizing challenges...

TAVI complications

17 Nov 2025 – From PCR London Valves 2025

This session delves into the management of complications arising during TAVI procedures, presenting real-world cases such as major vascular events including abdominal aortic dissection and catastrophic iliac artery perforation. It also covers technical solutions for valve embolisation and valve deformation due to calcific aorta, providing valuable...

TAVI: coronary protection

17 Nov 2025 – From PCR London Valves 2025

This session addresses coronary protection strategies during TAVI procedures, especially in complex scenarios such as valve-in-valve interventions, small annulus, and high-risk anatomy. It covers advanced techniques like BASILICA and bioprosthetic valve fracture, providing expert guidance on overcoming challenges to prevent coronary artery obstruction and optimize procedural...

TAVI in aortic regurgitation - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter aortic valve implantation in the setting of aortic regurgitation, a challenging clinical entity. It features novel techniques such as pump-assisted deployment and the use of deflectable self-expanding systems, as well as management of patients with prior valve-sparing aortic root surgery and...

TAVI: unusual complications - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session reviews unusual and severe complications encountered during TAVI procedures, such as aorto-right ventricular fistula, ventricular perforation, and sinus of Valsalva rupture. It highlights percutaneous treatment successes and endovascular interventions, offering critical insights into managing life-threatening procedural complications effectively.

Transcatheter mitral valve-in-valve: transcatheter rescue, balloon migration & more

17 Nov 2025 – From PCR London Valves 2025

This session addresses transcatheter mitral valve-in-valve and valve-in-ring interventions in complex clinical contexts. It includes cases of rescue procedures in valvular dysfunction, ECMO-assisted mitral valve-in-ring implantation in severe left ventricular dysfunction, and innovative approaches to mitral ring anatomy challenges, offering practical insights and procedural tips for...

Transcatheter mitral valve-in-valve: transcatheter rescue, balloon migration & more

Multiple valve interventions

17 Nov 2025 – From PCR London Valves 2025

This session delves into the complexities of multiple valve interventions, showcasing a fully transcatheter strategy for combined complex heart procedures. It presents stepwise approaches for managing multivalvular disease with severe pulmonary hypertension and sequential transcatheter strategies when single valve treatment is insufficient. Additional focus is given...

Complex combined interventions - Part 3

17 Nov 2025 – From PCR London Valves 2025

This session highlights complex combined transcatheter interventions, demonstrating simultaneous management of multiple valvular and aortic pathologies. Cases include percutaneous treatment of degenerated bioprosthetic valves, TAVI in rheumatic small annuli with multivalvular disease, and endovascular repair of ascending aortic pseudoaneurysm, illustrating comprehensive strategies for multifaceted cardiovascular disease.

Curious TAVI scenarios: solving complex anatomical and technical pitfalls

17 Nov 2025 – From PCR London Valves 2025

This session examines challenging and unusual scenarios encountered during transcatheter aortic valve implantation (TAVI). Topics include managing desaturation after transfemoral J-Valve implantation for pure NAVR, addressing procedural difficulties such as paddle release with Evolut TAVI, and utilizing snaring-assisted TAVI under cerebral embolic protection. It further explores...

Curious TAVI scenarios: solving complex anatomical and technical pitfalls

Percutaneous mitral balloon commissurotomy in unusual scenarios

17 Nov 2025 – From PCR London Valves 2025

This session examines percutaneous mitral balloon commissurotomy applied in unusual and challenging scenarios. It covers advanced techniques such as wire-guided Inoue balloon valvuloplasty post annuloplasty, strategies for severe mitral calcification, and innovative simplifications of established methods, emphasizing the ongoing relevance of this procedure in complex mitral...

Complications of transcatheter mitral valve replacement

17 Nov 2025 – From PCR London Valves 2025

This session addresses complications arising during transcatheter mitral valve replacement (TMVR), illustrated by challenging cases such as entangled snares, emergency interventions for prosthesis dislocation, vascular access difficulties, and repeat transapical mitral valve-in-valve replacements. It highlights the importance of anticipating and managing unexpected events to optimize patient...

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