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3177 results

Curious mitral and tricuspid scenarios

16 Nov 2025 – From PCR London Valves 2025

This session presents a series of challenging and unusual clinical scenarios involving mitral and tricuspid valve disease. Topics include management of acute primary mitral regurgitation in high-surgical-risk patients, technical challenges in transcatheter mitral valve replacement (TMVR), and complex cases where cardiac rhythm disturbances interplay with valvular...

Align for the future with next gen Myval transcatheter heart valve series

16 Nov 2025 – From PCR London Valves 2025

Discover how the latest Myval transcatheter heart valve (THV) innovations are shaping TAVI outcomes. This PCR London Valves 2025 session highlights the clinical evidence behind the next-gen Myval THV series, best practices for implantation, and upcoming innovations set to improve patient care. Learn step-by-step techniques for deploying Myval...

Align for the future with next gen Myval transcatheter heart valve series

Cardiovalve hits the TARGET: advancing transcatheter valve replacement

18 Nov 2025 – From PCR London Valves 2025

This session highlights the features and procedural steps of the next-generation Cardiovalve systems for tricuspid and mitral valve replacement. It reviews interim results from the TARGET study, emphasizing echocardiographic findings and reverse remodeling effects, and discusses best practices for patient selection and the learning pathway to...

Cardiovalve hits the TARGET: advancing transcatheter valve replacement

TAVI in aortic regurgitation

16 Nov 2025 – From PCR London Valves 2025

This session addresses the challenges and innovations in transcatheter aortic valve implantation (TAVI) for aortic regurgitation. It covers complex clinical scenarios such as severe regurgitation post-endocarditis, alternative access routes complicated by prosthesis embolisation, and the use of dedicated TAVI devices in non-tricuspid valves. The session also...

TAVI-in-TAVI

16 Nov 2025 – From PCR London Valves 2025

This session explores the nuanced field of TAVI-in-TAVI procedures, focusing on valve durability considerations between bovine and porcine valves, strategies for redo TAVI post valve-in-valve, and advanced interventions to secure coronary flow such as inter-valvular stenting. It highlights complex anatomical challenges including aberrant coronary origins and...

Valve interventions in congenital heart disease

16 Nov 2025 – From PCR London Valves 2025

This session presents complex valve interventions in congenital heart disease, highlighting challenging cases such as positional hypoxaemia due to iatrogenic atrial defects, navigating residual shunts after PFO closure, and transcatheter pulmonary valve replacement in native right ventricular outflow tracts without pre-stenting. It also examines an intriguing...

A new era for aortic regurgitation: how new guidelines and dedicated devices for AR will redefine treatment

18 Nov 2025 – From PCR London Valves 2025

This session examines the evolving treatment landscape for aortic regurgitation (AR) in light of new ESC guidelines and dedicated devices such as the JenaValve Trilogy System. It provides an in-depth look at refined diagnosis, optimized treatment strategies, and presents real-world data and clinical cases that highlight...

A new era for aortic regurgitation: how new guidelines and dedicated devices for AR will redefine treatment

Getting the full potential of the supra-annular valve in a changing landscape

16 Nov 2025 – From PCR London Valves 2025

This session explores the evolving landscape of transcatheter aortic valve implantation (TAVI) with a focus on supra-annular valve technology. It covers techniques for achieving commissural alignment, considerations for small aortic annuli, and advantages in treating bicuspid aortic valve disease, supported by clinical data and illustrative cases.

Getting the full potential of the supra-annular valve in a changing landscape

From repair to replacement: a portfolio of options for your mitral and tricuspid regurgitation patients

16 Nov 2025 – From PCR London Valves 2025

This session explores a full spectrum of therapeutic options for mitral and tricuspid regurgitation, focusing on the PASCAL Precision system for targeted repair and the SAPIEN M3 transcatheter mitral valve replacement. Through beating heart simulators, case discussions, and clinical evidence, participants will understand the versatility and...

From repair to replacement: a portfolio of options for your mitral and tricuspid regurgitation patients

Hot topics in structural heart: addressing patients' unmet needs with EVOQUE TTVR and SAPIEN THV-in-THV

17 Nov 2025 – From PCR London Valves 2025

This session addresses emerging topics in structural heart disease by examining patient-centered solutions such as EVOQUE transcatheter tricuspid valve replacement (TTVR) and SAPIEN transcatheter heart valve-in-heart valve (THV-in-THV) procedures. It covers the latest data from Europe on redo TAVI, lifetime management strategies beginning with initial prosthesis...

Hot topics in structural heart: addressing patients' unmet needs with EVOQUE TTVR and SAPIEN THV-in-THV

Late-Breaking Trials in transcatheter mitral, tricuspid and aortic interventions - Part 1

16 Nov 2025 – From PCR London Valves 2025

This session presents pivotal late-breaking trials in transcatheter mitral and aortic valve interventions. Explore one-year outcomes from the AltaValve early feasibility study featuring atrial fixation TMVR, interim results from the TARGET study assessing Cardiovalve for tricuspid regurgitation, five-year data on transapical TMVR, and outcomes of TAVI...

The Top Late-Breaking Trials - Part 1

CHOICE-CLOSURE: a randomized trial of plug-based versus suture-based large-bore vascular closure

06 Nov 2021

TCT 2021: Radoslaw Parma reviews the CHOICE-CLOSURE multicentre, randomized, controlled, open-label clinical trial presented by Mohamed Abdel-Wahab. The study compared outcomes of percutaneous femoral artery closure using a plug-based and a primary suture-based strategy in patients undergoing TAVI.

Author

Radoslaw Parma
CHOICE-CLOSURE: a randomized trial of plug-based versus suture-based large-bore vascular closure

The PASCAL IID Registry: A prospective registry for transcatheter edge-to-edge repair in prohibitive risk patients with degenerative mitral regurgitation and complex mitral valve anatomy

17 Sep 2022

Alex Sticchi provides his take on the PASCAL IID Registry and an initial comparison with the CLASP IID. The trial was presented by Jörg Hausleiter during TCT Congress 2022.

Alessandro Sticchi

Author

Alessandro Sticchi
The PASCAL IID Registry: A Prospective Registry for Transcatheter Edge-to-Edge Repair in Prohibitive Risk Patients With Degenerative MR and Complex Mitral Valve Anatomy

Successful rotablation of a calcium spike blocking the motion of a mechanical prosthetic leaflet

27 Mar 2023

Thanks to this EIJ image, consider the case of a 46-year-old female patient who underwent a first aortic valve replacement at the age of 25, a second one 10 years later, together with a mitral valve replacement, and who presented with a displaced calcium spike from...

Successful rotablation of a calcium spike blocking the motion of a mechanical prosthetic leaflet

Feasibility of sheathless Impella for protected percutaneous coronary intervention: a single-center experience

02 May 2025

Impella CP microaxial flow pump supports complete revascularisation during high-risk PCI, but standard implantation often leads to vascular complications. This article explores an initial experience with a sheathless implantation technique, which shows promise as a feasible and safe alternative.

Sheathless Impella PCI

Routine cerebral embolic protection in transcatheter aortic valve implantation: the British Heart Foundation (BHF) PROTECT-TAVI trial

29 Mar 2025

Aaysha Cader and Ali Nazmi Calik provide their take on the BHF PROTECT-TAVI trial, presented by Rajesh Kharbanda at ACC.25 in Chicago.

Author

Aaysha Cader

Author

Ali Nazmi Calik
Routine cerebral embolic protection in TAVI: the British Heart Foundation (BHF) PROTECT-TAVI trial

Intravascular ultrasound-guided versus angiography-guided percutaneous coronary intervention in acute coronary syndromes: The multicenter, randomized, blinded, IVUS-ACS Trial

09 Apr 2024

Marco Spagnolo and Daniele Giacoppo report the main results of the IVUS-ACS trial presented by Shao-Liang Chen, from the Nanjing First Hospital, Nanjing Medical University, Nanjing, in a Featured Clinical Research session at ACC.24 in Atlanta and simultaneously published in The Lancet.(1)

Daniele Giacoppo

Author

Daniele Giacoppo
Marco Spagnolo

Author

Marco Spagnolo
IVUS-guided vs angiography-guided PCI in acute coronary syndromes
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