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Transcatheter solutions in young and congenital heart disease patients

17 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter solutions tailored for young and congenital heart disease patients, featuring challenging edge-to-edge repair in extracardiac Fontan physiology, systemic AV valve TEER in congenital anomalies, multidisciplinary management of repaired tetralogy of Fallot with tricuspid regurgitation, innovative TAVI in young congenital patients, and...

Pills and pumps: targeting heart failure before and after surgical and transcatheter valve interventions

18 Nov 2025 – From PCR London Valves 2025

This session examines the integrated role of heart failure therapies in the peri- and post-procedural management of patients undergoing surgical and transcatheter valve interventions. It reviews current and emerging clinical trial data, discusses identifying high-risk patients, and explores advanced modalities such as cardiac resynchronization and circulatory...

Pills and pumps: targeting heart failure before and after surgical and transcatheter valve interventions

Getting to the heart of access: mastering femoral puncture and vascular closure

18 Nov 2025 – From PCR London Valves 2025

This session provides an in-depth understanding of femoral anatomy and the critical role of imaging in ensuring safe vascular access via femoral puncture. It covers the latest equipment used for vascular access and closure, highlighting haemostasis techniques and closure devices. Interactive case scenarios offer practical insights...

Featured research - Mitral valve interventions - Part 4

18 Nov 2025 – From PCR London Valves 2025

This research-focused session presents contemporary evidence and clinical outcomes related to mitral valve interventions. It includes data on transapical mitral valve-in-ring implantation from the European Tendyne registry, prognostic utility of CT-derived fatty muscle fraction in mitral TEER, and comparative outcomes between transapical TMVR and mitral TEER....

Paravalvular leak closure - Part 3

18 Nov 2025 – From PCR London Valves 2025

This session addresses the complexities of paravalvular leak closure, emphasizing resilience in procedural approaches. It covers sizing balloon techniques that enhance treatment efficacy in aortic paravalvular leaks and explores closure strategies following Ozaki procedures. Management of mitral paravalvular leaks in high-risk patients and innovative solutions for...

TAVI complications - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session explores complex and uncommon complications associated with TAVI procedures, highlighting challenging clinical scenarios such as neurological complications in bicuspid valves, management of critically unstable left ventricles, and outcomes in complex valve interventions. Each topic offers valuable lessons for improving procedural safety and patient outcomes...

Featured research - TAVI - Part 14

18 Nov 2025 – From PCR London Valves 2025

This featured research session presents pivotal findings on transcatheter aortic valve implantation (TAVI), including 30-day and one-year outcomes from the VANTAGE trial, novel concepts for assessing aortic stenosis severity, and the influence of mitral annular calcification on conduction disturbances. Additional topics cover the role of clinical...

TAVI in challenging anatomies

18 Nov 2025 – From PCR London Valves 2025

This session focuses on the challenges of performing TAVI in complex anatomical settings. It covers issues such as valve compression, hypertrophic cardiomyopathy-related left ventricular responses, alternative management strategies during crises, and handling anatomical complexities like membranous septal aneurysm at the annulus and sinus of Valsalva in...

Stratified treatment of myocardial infarction with non-obstructive coronary arteries: the PROMISE trial

31 Oct 2025

Nicola Ryan provides her take on the PROMISE trial presented by Rocco Antonio Montone at TCT 2025, in San Francisco.

Nicola Ryan

Author

Nicola Ryan
Stratified treatment of myocardial infarction with non-obstructive coronary arteries: the PROMISE trial

Impella percutaneous ventricular assist device malrotation in social media: a call to action

20 Apr 2023

The data from this study suggest that, from a SoMe perspective, correct Impella orientation is often overlooked, and that Impella malrotation is a common issue in real-world clinical practice, potentially associated with relevant complications. 

Alessandro Beneduce

Author

Alessandro Beneduce
Luca Baldetti

Author

Luca Baldetti

Author

Anna Mara Scandroglio
Mamas Mamas

Author

Mamas Mamas
Alaide Chieffo

Author

Alaide Chieffo
Impella pVAD Malrotation in social media

The CLEAR SYNERGY (OASIS 9) Trial: A 2x2 factorial randomized controlled trial of colchicine versus placebo and spironolactone versus placebo in patients with myocardial infarction

18 Nov 2024

Mirvat Alasnag provides her take on the CLEAR SYNERGY trial presented by Sanjit S Jolly at AHA 2024 in Chicago.

Dr. Mirvat Alasnag

Author

Mirvat Alasnag
CLEAR SYNERGY

NOTION-3 - Percutaneous coronary intervention in patients undergoing transcatheter aortic valve implantation

01 Sep 2024

Make the most of the insights from Jacob Thomsen Loenborg’s interview with Chiara De Biase and Ali Nazmi Calik’s article to capture the key takeaways from this trial, simultaneously published in the NEJM, presented at the ESC Congress 2024 in London.

Author

Chiara De Biase
Jacob Lønborg

Author

Jacob Lønborg

Author

Ali Nazmi Calik
NOTION 3

Evidence base: A description of the key, so far published, studies in the space of drug coated balloons

23 Jan 2025

Authored by Hector Garcia-Garcia and Jorge Sanz-Sanchez, this article examines pivotal randomized clinical trials on drug-coated balloons in coronary artery disease. It highlights their role in managing in-stent restenosis, de novo small vessel lesions, and large vessel lesions while exploring future directions through ongoing trials.

Author

Hector Garcia-Garcia
Jorge Sanz Sanchez

Author

Jorge Sanz-Sanchez
Evidence base: A description of the key, so far published, studies in the space of drug coated balloons
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