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Complex valve-in-valve leaflet modification - LIVE Case

17 Nov 2025 – From PCR London Valves 2025

Watch this LIVE case followed by a recorded case, regarding a 79-year-old male with permanent AF and a history of surgical aortic valve replacement in 2010 (Magna Ease 25) who presented with symptomatic bioprosthetic valve stenosis, normal LV function, and no CAD. A Sapien 3 Ultra...

Complex valve-in-valve leaflet modification - LIVE Case

Paravalvular leak closure - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session is dedicated to paravalvular leak (PVL) closure techniques, featuring percutaneous approaches after surgical valve implantation and TAVI complications such as annulus rupture. It includes advanced management using multiple plugs for long-tunnel mitral PVLs, innovative transformation from pop-up to plug strategies, and transapical approaches following...

Tricuspid interventions: knowns and unknowns

17 Nov 2025 – From PCR London Valves 2025

Explore the evolving landscape of transcatheter tricuspid valve interventions in this session, which presents the latest evidence from registries and randomized trials. Discussions include the new Euro tricuspid regurgitation risk score, clinical controversies, real-world patient scenarios, and insights into optimal medical therapy and device selection to...

Tricuspid interventions: knowns and unknowns

TAVI for pure aortic regurgitation: different animal, different challenges, different approaches

17 Nov 2025 – From PCR London Valves 2025

This session delves into the unique anatomical and pathophysiological challenges posed by pure aortic regurgitation and their impact on treatment strategies. It reviews clinical outcomes with established and new transcatheter devices, and presents emerging technologies that promise to advance therapeutic options for this distinct patient population.

TAVI for pure aortic regurgitation: different animal, different challenges, different approaches

Transcatheter mitral valve-in-valve, valve-in-ring, and valve-in-MAC

17 Nov 2025 – From PCR London Valves 2025

This session provides an expert overview of transcatheter mitral valve-in-valve, valve-in-ring, and valve-in-MAC procedures. It focuses on unique anatomical and technical considerations, advanced imaging and pre-procedural planning methods, and procedural techniques including device selection and sizing, guided by experienced high-volume operators to optimize procedural success.

Transcatheter mitral valve-in-valve, valve-in-ring, and valve-in-MAC

From diagnosis to device: decision-making and planning for mitral valve interventions

17 Nov 2025 – From PCR London Valves 2025

This session offers a comprehensive overview of decision-making and procedural planning for transcatheter mitral valve interventions. It emphasizes patient-specific factors, advanced imaging for valve morphology assessment, device selection, and the integration of emerging technologies to tailor optimal treatment strategies for mitral valve disease.

From diagnosis to device: decision-making and planning for mitral valve interventions

Featured research - Tricuspid valve intervention: the TRIPLACE registry

17 Nov 2025 – From PCR London Valves 2025

This session features cutting-edge research on tricuspid valve interventions, including insights from the TRIPLACE registry on orthotopic TTVR thrombosis, predictive value of three-dimensional tricuspid annulus measurements for procedural outcomes, early clinical experiences with novel TTVR systems, and procedural clipping strategies based on results from the BRIGHT...

Featured research - Tricuspid valve intervention: the TRIPLACE registry

Featured research - TAVI: Predictive tools, AI innovation and reintervention strategies

17 Nov 2025 – From PCR London Valves 2025

This session presents cutting-edge research in TAVI, covering the development of predictive models for clinical valve thrombosis, comparative analyses between self-expandable and balloon-expandable valves from the Greek TAVI registry, and the emerging role of AI-guided Heart Team decisions. It also examines outcomes of reintervention strategies following...

Featured research - TAVI: Predictive tools, AI innovation and reintervention strategies

Early Career Research Award Final

17 Nov 2025 – From PCR London Valves 2025

Highlighting pioneering research in structural heart interventions, this session presents studies on the impact of transcatheter tricuspid valve replacement (TTVR) on left ventricular geometry and function, myocardial remodeling in aortic stenosis, physiological responses after mitral and tricuspid edge-to-edge repairs, advancing the understanding of device effects on...

TAVI valve-in-valve - Challenging clinical scenarios

17 Nov 2025 – From PCR London Valves 2025

This session focuses on the complexities of valve-in-valve TAVI procedures, highlighting challenging clinical scenarios such as managing severely regurgitant rapid deployment valves and degenerated stentless bioprostheses. It provides detailed insights into overcoming procedural barriers and strategies for complex valve-in-valve transcatheter aortic valve replacement (TAVR) interventions.

TAVI valve-in-valve - Challenging clinical scenarios

Learning from lived experience and contemporary evidence: shaping the treatment of women with heart valve disease

17 Nov 2025 – From PCR London Valves 2025

This session provides an in-depth exploration of the lived experiences of women with valvular heart disease, emphasizing the unique challenges in detection, diagnosis, treatment, and follow-up. It integrates contemporary evidence and the forthcoming 2025 ESC/EACTS guidelines to offer practice-ready strategies tailored to the management of valvular...

Featured research - Mitral valve interventions: Physiology & device innovation

17 Nov 2025 – From PCR London Valves 2025

This session highlights groundbreaking research on mitral valve interventions featuring advanced transcatheter techniques. Topics include coronary physiology assessment with vFFR in severe mitral regurgitation, predictive versus actual outcomes in TMVR, innovative devices like Epygon and INNOVALVE, and novel approaches such as the ReNiva posterior leaflet replacement...

Featured research - Mitral valve interventions: Physiology & device innovation

TAVI: challenging anatomies

17 Nov 2025 – From PCR London Valves 2025

This session explores the management of challenging anatomical conditions in TAVI procedures. Topics include strategies for difficult self-expandable valve delivery angles, addressing complications occurring during and after TAVI, and approaches for patients with severe kyphosis or complex structural abnormalities such as aneurysms and septal anomalies.

Left atrial appendage occlusion

17 Nov 2025 – From PCR London Valves 2025

This session focuses on the complexities and innovations in left atrial appendage occlusion (LAAO) procedures. It covers transesophageal ICE monitoring, challenges posed by existing atrial septal occluders, combined surgical and percutaneous approaches, and the practical experience with the Ultraseal device. These insights advance understanding of procedural...

Mitral interventions in shock

17 Nov 2025 – From PCR London Valves 2025

This session highlights the intricacies of mitral valve interventions in the context of cardiogenic shock. It addresses complex cases including left-to-right shunts post septal puncture, severe ischemic mitral insufficiency with small valve anatomy, emergency mitral TEER for papillary muscle rupture, and bridging strategies to surgery.

TAVI: complex vascular access

17 Nov 2025 – From PCR London Valves 2025

This session addresses the challenges of complex vascular access in transcatheter aortic valve implantation (TAVI). It discusses strategies for navigating difficult thoraco-abdominal aortic anatomies, managing double aortic arches, and overcoming hostile femoral access. Case studies illustrate meticulous planning and innovative solutions essential for successful TAVI in...

TAVI in shock

17 Nov 2025 – From PCR London Valves 2025

This session presents advanced cases of TAVI performed in patients experiencing cardiogenic shock. It includes valve-in-valve TAVI under ECMO support, innovative antegrade-retrograde crossing techniques for legacy surgical bioprostheses, and management of acute aortic regurgitation following prosthesis failure or TAVI.

TAVI: nightmare in the cathlab - Annular perforation, coronary obstruction & balloon rupture

17 Nov 2025 – From PCR London Valves 2025

This session presents critical case analyses of complicated TAVI procedures, highlighting unexpected and severe intra-procedural events such as annular perforation, leaflet modification complications, coronary obstructions, and device failures. It emphasizes prevention strategies, bailout techniques, and acute management to prepare clinicians for handling TAVI-related emergencies effectively.

TAVI: nightmare in the cathlab - Annular perforation, coronary obstruction & balloon rupture

Paravalvular leak closure - Part 1

17 Nov 2025 – From PCR London Valves 2025

This session focuses on paravalvular leak closure challenges and solutions. It features complex cases such as extraction of plugs jailed between mechanical valves, managing leaks associated with severe annular calcification, aorto-mitral curtain leaks, device embolisation post-TMVR, and device-related haemolysis after closure procedures.

Challenging mitral TEER: Barlow's disease, fibro-elastic deficiency & abnormal valve morphology

17 Nov 2025 – From PCR London Valves 2025

This session examines the feasibility and technical considerations of mitral transcatheter edge-to-edge repair (TEER) in complex anatomical and pathological scenarios. Topics include applications in Barlow's disease, fibro-elastic deficiency, congenital heart anomalies, Anderson-Fabry disease, and post-cardiac transplantation, providing valuable insights into expanding TEER indications and overcoming anatomical...

Challenging mitral TEER: Barlow's disease, fibro-elastic deficiency & abnormal valve morphology
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