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Featured research - TAVI: Predictive tools, AI innovation and reintervention strategies

17 Nov 2025 – From PCR London Valves 2025

This session presents cutting-edge research in TAVI, covering the development of predictive models for clinical valve thrombosis, comparative analyses between self-expandable and balloon-expandable valves from the Greek TAVI registry, and the emerging role of AI-guided Heart Team decisions. It also examines outcomes of reintervention strategies following...

Featured research - TAVI: Predictive tools, AI innovation and reintervention strategies

TAVI: vascular complications

16 Nov 2025 – From PCR London Valves 2025

This session examines vascular complications associated with transfemoral TAVI procedures, featuring challenging cases such as initial procedural obstacles, complex post-TAVI vascular events, and unusual complications. It also explores advanced techniques like intravascular lithotripsy to optimize TAVI outcomes in patients with severe calcific iliofemoral disease.

TAVI valve-in-valve - Challenging clinical scenarios

17 Nov 2025 – From PCR London Valves 2025

This session focuses on the complexities of valve-in-valve TAVI procedures, highlighting challenging clinical scenarios such as managing severely regurgitant rapid deployment valves and degenerated stentless bioprostheses. It provides detailed insights into overcoming procedural barriers and strategies for complex valve-in-valve transcatheter aortic valve replacement (TAVR) interventions.

TAVI valve-in-valve - Challenging clinical scenarios

TAVI: high coronary risk - Part 2

16 Nov 2025 – From PCR London Valves 2025

This session presents advanced strategies to mitigate high coronary risk during valve-in-valve TAVR procedures, including the LLAMACORN technique and chimney stenting to prevent coronary obstruction. It discusses management of misaligned prostheses, complex aortic and coronary anatomies, and innovative approaches such as stent crush techniques to ensure...

TAVI: alternative access

17 Nov 2025 – From PCR London Valves 2025

This session addresses alternative access routes for TAVI in patients with challenging vascular anatomies. It includes innovative approaches such as transapical TAV-in-TAV procedures, transcaval implantation in emergency settings, and techniques for patients with hostile iliofemoral access, showcasing adaptive strategies when conventional access is not feasible.

TAVI: challenging anatomies

17 Nov 2025 – From PCR London Valves 2025

This session explores the management of challenging anatomical conditions in TAVI procedures. Topics include strategies for difficult self-expandable valve delivery angles, addressing complications occurring during and after TAVI, and approaches for patients with severe kyphosis or complex structural abnormalities such as aneurysms and septal anomalies.

Complex mitral and tricuspid TEER

16 Nov 2025 – From PCR London Valves 2025

This session highlights complex cases in mitral and tricuspid transcatheter edge-to-edge repair (TEER), addressing challenges such as septal obstacles in patients with old atrial septal occluders, management of residual atrial septal defects post-mitral valve-in-ring replacement, and innovative multidisciplinary approaches. It also covers hybrid transapical mitral valve-in-valve...

The index valve matters: optimal index TAVI for a lifetime of possibilities

18 Nov 2025 – From PCR London Valves 2025

Discover how thoughtful index valve selection and implantation techniques can shape the long-term management of patients undergoing TAVI. This PCR London Valves 2025 session highlights treatment considerations for low- and intermediate-risk patients, explores how valve choice affects the feasibility of future interventions, and examines strategies to...

The index valve matters: optimal index TAVI for a lifetime of possibilities

The next frontier in LAA closure: innovations and opportunities

17 Nov 2025 – From PCR London Valves 2025

Explore the forefront of left atrial appendage (LAA) closure with this session focusing on the latest innovations and clinical opportunities. Topics include recent data on WATCHMAN FLX PRO and VersaCross Connect systems, workflow strategies to improve procedural efficiency, and discussions on upcoming clinical trials such as...

The next frontier in LAA closure: innovations and opportunities

On-site computed tomography-derived fractional flow reserve to guide the management of patients with stable coronary artery disease: The TARGET randomized trial

05 Mar 2023

Mirvat Alasnag provides her take on this clinical trial presented by Yundai Chen at the American College of Cardiology Scientific Session (ACC.23/WCC).

Dr. Mirvat Alasnag

Author

Mirvat Alasnag
On-site computed tomography-derived fractional flow reserve to guide the management of patients with stable coronary artery disease: The TARGET randomized trial

Drug-coated balloon (DCB) technology: A pioneer’s view of the historical evolution and future directions

08 Jan 2025

In this article, Bruno Scheller explores advances in local drug delivery, from drug-coated balloons to novel antiproliferative agents. These innovations aim to reduce restenosis, minimize permanent implants, and pave the way for patient-specific coronary artery disease treatments.

Author

Bruno Scheller
Drug-coated balloon (DCB) technology: A pioneer’s view of the historical evolution and future directions
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