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Featured research - TAVI: Predictive tools, AI innovation and reintervention strategies

17 Nov 2025 – From PCR London Valves 2025

This session presents cutting-edge research in TAVI, covering the development of predictive models for clinical valve thrombosis, comparative analyses between self-expandable and balloon-expandable valves from the Greek TAVI registry, and the emerging role of AI-guided Heart Team decisions. It also examines outcomes of reintervention strategies following...

Featured research - TAVI: Predictive tools, AI innovation and reintervention strategies

Featured research - Tricuspid valve intervention: the TRIPLACE registry

17 Nov 2025 – From PCR London Valves 2025

This session features cutting-edge research on tricuspid valve interventions, including insights from the TRIPLACE registry on orthotopic TTVR thrombosis, predictive value of three-dimensional tricuspid annulus measurements for procedural outcomes, early clinical experiences with novel TTVR systems, and procedural clipping strategies based on results from the BRIGHT...

Featured research - Tricuspid valve intervention: the TRIPLACE registry

Paravalvular leak closure - Part 1

17 Nov 2025 – From PCR London Valves 2025

This session focuses on paravalvular leak closure challenges and solutions. It features complex cases such as extraction of plugs jailed between mechanical valves, managing leaks associated with severe annular calcification, aorto-mitral curtain leaks, device embolisation post-TMVR, and device-related haemolysis after closure procedures.

Unravel the complexity of multi-valve disease

17 Nov 2025 – From PCR London Valves 2025

This session unpacks the complexities inherent in multi-valve disease involving combined mitral and tricuspid regurgitation. It emphasizes diagnostic challenges, the critical role of invasive hemodynamics in decision-making, and strategies for optimal timing and staging of interventions, demonstrated through illustrative patient cases.

Unravel the complexity of multi-valve disease

Interventions in shock

17 Nov 2025 – From PCR London Valves 2025

This session addresses critical interventions in cardiogenic shock, highlighting innovative approaches such as combined valve procedures, management of acute functional mitral regurgitation in STEMI, and advanced transcatheter edge-to-edge repair techniques in refractory heart failure. It offers a comprehensive exploration of strategies to navigate complex hemodynamic instability...

TAVI Valve-in-Valve: Managing unexpected anatomical challenges

17 Nov 2025 – From PCR London Valves 2025

This session examines valve-in-valve interventions in TAVI, highlighting management of concomitant left main disease, unique case narratives such as "The Highlander story," and the unpredictability inherent in these procedures. It also reviews successful transfemoral TAV-in-SAV interventions in acute heparin-induced thrombocytopenia and addresses treatment of degenerated sutureless...

TAVI Valve-in-Valve: Managing unexpected anatomical challenges

Transcatheter mitral valve-in-valve: alternative strategy for optimal alignment

17 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter mitral valve-in-valve procedures, emphasizing alternative strategies for optimal alignment and lifetime management planning. It delves into engineering the landing zone for challenging anatomies, the integration of the LAMPOON procedure in TMVR valve-in-valve cases, and addresses complexities arising from mitral annular calcification.

Transcatheter mitral valve-in-valve: alternative strategy for optimal alignment

Featured research - TAVI: procedural optimization

17 Nov 2025 – From PCR London Valves 2025

Delve into comprehensive analyses of TAVI procedural outcomes and innovations in this session. Topics include the impact of intercoronary angles on coronary overlap with Evolut valves, mechanisms behind superior outcomes with the latest balloon-expandable valves, and predictive modeling of hemodynamics using physics-enhanced digital twins. Additionally, sex-specific...

Featured research - TAVI: procedural optimization

TAVI complications - Part 4

18 Nov 2025 – From PCR London Valves 2025

This session focuses on complex complications encountered in TAVI procedures, presenting challenging cases such as combined adverse events, wire-related technical difficulties, differential diagnosis between hypoattenuated leaflet thickening and infective endocarditis one year post-TAVI, issues caused by fractured sheath tips impacting valve expansion, and sinus breaches. These...

Getting to the heart of access: mastering femoral puncture and vascular closure

18 Nov 2025 – From PCR London Valves 2025

This session provides an in-depth understanding of femoral anatomy and the critical role of imaging in ensuring safe vascular access via femoral puncture. It covers the latest equipment used for vascular access and closure, highlighting haemostasis techniques and closure devices. Interactive case scenarios offer practical insights...

Thrombotic complications of transcatheter valves

17 Nov 2025 – From PCR London Valves 2025

Focusing on thrombotic complications following transcatheter valve implantation, this session presents a series of complex cases illustrating acute and late thrombotic events, their clinical presentations, and the pivotal role of multimodality imaging in diagnosis and management. Insights include coronary embolism and cardiogenic shock scenarios, emphasizing challenges...

Featured research - Mitral valve interventions - Part 4

18 Nov 2025 – From PCR London Valves 2025

This research-focused session presents contemporary evidence and clinical outcomes related to mitral valve interventions. It includes data on transapical mitral valve-in-ring implantation from the European Tendyne registry, prognostic utility of CT-derived fatty muscle fraction in mitral TEER, and comparative outcomes between transapical TMVR and mitral TEER....

Complications of transcatheter mitral valve replacement

17 Nov 2025 – From PCR London Valves 2025

This session addresses complications arising during transcatheter mitral valve replacement (TMVR), illustrated by challenging cases such as entangled snares, emergency interventions for prosthesis dislocation, vascular access difficulties, and repeat transapical mitral valve-in-valve replacements. It highlights the importance of anticipating and managing unexpected events to optimize patient...

TAVI: nightmare in the cathlab - Part 3

18 Nov 2025 – From PCR London Valves 2025

This session reviews challenging complications encountered during TAVI procedures, highlighting emergent situations such as coronary occlusion and cardiac arrest. It also discusses unique cases including bicuspid aortic valve-related haemolysis, novel vascular access approaches like lithotripsy, and successful management of double perforation complications. The session provides critical...

TAVI: complex vascular access - Part 3

18 Nov 2025 – From PCR London Valves 2025

This session focuses on managing complex vascular access challenges in TAVI procedures. It includes case discussions on non-crossable aortic valve stenosis, transseptal TAVI for severe aortic regurgitation with porcelain aorta, and percutaneous implantation in patients with unconventional anatomy or conditions like shaggy syndrome. Strategies for severe...

From GDMT to TEER: management of secondary mitral regurgitation and the timing of transcatheter intervention

18 Nov 2025 – From PCR London Valves 2025

Delve into the comprehensive management of secondary mitral regurgitation, from guideline-directed medical therapy (GDMT) to transcatheter edge-to-edge repair (TEER). This session elucidates the pathophysiology of atrial and ventricular secondary mitral regurgitation, explores optimized heart failure treatments, and reviews the latest evidence on TEER as a therapeutic...

From GDMT to TEER: management of secondary mitral regurgitation and the timing of transcatheter intervention

TAVI valve-in-valve - Part 6

18 Nov 2025 – From PCR London Valves 2025

This session explores valve-in-valve TAVI procedures, addressing intricate cases such as triple valve scenarios, planning challenges in TAVI-in-TAVI, and overcoming obstacles in mitral valve-in-valve therapies. It also presents difficult cases involving dysfunctional stentless aortic bioprostheses and acute leaflet rupture during valve replacement, offering practical insights for...

The index valve matters: optimal index TAVI for a lifetime of possibilities

18 Nov 2025 – From PCR London Valves 2025

Discover how thoughtful index valve selection and implantation techniques can shape the long-term management of patients undergoing TAVI. This PCR London Valves 2025 session highlights treatment considerations for low- and intermediate-risk patients, explores how valve choice affects the feasibility of future interventions, and examines strategies to...

The index valve matters: optimal index TAVI for a lifetime of possibilities

The next frontier in LAA closure: innovations and opportunities

17 Nov 2025 – From PCR London Valves 2025

Explore the forefront of left atrial appendage (LAA) closure with this session focusing on the latest innovations and clinical opportunities. Topics include recent data on WATCHMAN FLX PRO and VersaCross Connect systems, workflow strategies to improve procedural efficiency, and discussions on upcoming clinical trials such as...

The next frontier in LAA closure: innovations and opportunities

TAVI: nightmare in the cathlab - Cardiac arrest, aortic root rupture & duct occluder

16 Nov 2025 – From PCR London Valves 2025

Explore critical complications encountered during TAVI procedures in this session, which highlights urgent scenarios such as cardiac arrest from calcific leaflet shift, aortic root rupture, and embolisation events. It also covers salvage techniques like TAVR-in-TAVR-in-SAVR in cardiogenic shock and management of acute left main occlusion with...

TAVI: nightmare in the cathlab - Cardiac arrest, aortic root rupture & duct occluder
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