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Bifurcation lesions

Find all the latest content on bifurcation lesions published on this website.

The percutaneous treatment of coronary bifurcation lesions is very dynamic with an ongoing evolution in clinical approaches and techniques and the management of more complex cases continuing to evolve. Keep up-to-date about all these changes along with the latest research and devices as well as advances in imaging, the use of adjunctive pharmacotherapy, vascular access or understanding bleeding risks. Use the filters below to access PCRonline resources.

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Bifurcation lesion

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Coronary bifurcation lesions

08 Jul 2025

This updated chapter by T. Lefèvre provides a practical guide on strategies currently implemented in the treatment of coronary bifurcations, and highlights the main challenges and most debated issues to propose recommendations for an optimal approach. 

Authors :

Lefèvre T., Hovasse T.
The PCR Textbook chapter on Bifurcation lesions

PCI for complex bifurcation disease - LIVE Case

23 May 2025 – From EuroPCR 2025

A 60-year-old male patient presented with an inferior STEMI one month ago, which was treated with RCA and LCx PCI. He was referred for LAD/diagonal PCI. The LV function was reduced (EF 45 %). The team performed a DK crush PCI, guided by IVUS.

LIVE Educational Case...

PCI for complex bifurcation disease - LIVE Case

Complex multivessel disease - LIVE Case

21 May 2025 – From EuroPCR 2025

An 89-year-old male patient presented with stable angina, preserved LV function and some risk factors such as hypertension and diabetes. CT scan and angiography revealed occlusion of proximal RCA and bifurcation lesions on LAD and circumflex (medina 1,1,1). Operators treated the bifurcation lesions with provisional stenting.
Regarding...

Complex multivessel disease - LIVE Case

What are the essentials of the provisional strategy for non-left main true bifurcation lesions?

21 May 2025 – From EuroPCR 2025

Giuseppe Di Gioia and Jens Flensted Lassen explore the essentials of the provisional stenting strategy for non-left main true bifurcation lesions. This stepwise approach offers simplicity while preserving flexibility: start with one stent in the main vessel, and keep the option open for a second if...

What are the essentials of the provisional strategy for non-left main true bifurcation lesions?

What are the fundamentals of an upfront two-stent strategy for bifurcation PCI?

21 May 2025 – From EuroPCR 2025

Nicola Ryan explores the fundamentals of an upfront two-stent strategy in bifurcation PCI with Dejan Milasinovic. When the side branch shows significant, high-grade stenosis or extensive disease, direct treatment—via POBA, DCB, or a second stent—may be preferred. Anatomy guides the decision between provisional and two-stent strategies,...

What are the fundamentals of an upfront two-stent strategy for bifurcation PCI?

How to successfully approach calcified bifurcation lesions?

20 May 2025 – From EuroPCR 2025

Calcified bifurcation lesions remain one of the toughest challenges in interventional cardiology, combining two high-risk features into one complex scenario.

In this EuroPCR 2025 interview, Dejan Milasinovic, Miroslaw Ferenc, and Mohamed Abdel Wahab explain why this subset deserves dedicated attention. They highlight the critical role of intra-coronary...

How to successfully approach calcified bifurcation lesions?

Comparison of stent geometry achieved by different side-branch ballooning techniques for bifurcation provisional stenting: the CRABBIS Trial

31 Mar 2025

Which ballooning technique is best after main vessel stenting in bifurcation PCI? This two-part study compares two key approaches: PKP (POT, kissing balloon inflation, final POT) and PSP (POT, isolated side branch dilation, final POT) to determine the optimal strategy.

Reviewer

Ali Nazmi Calik

Reviewer

Aaysha Cader
Comparison of stent geometry achieved by different side-branch ballooning techniques for bifurcation provisional stenting: the CRABBIS Trial

Precision PCI in the era of AI and multimodality imaging

13 Jan 2025

Nailing the ostium of LAD, although technically challenging, can be precisely done with mandatory intracoronary imaging. It is essential to rule out disease extension into left main artery as, otherwise, cross over LM-LAD stenting strategy would be preferable. CTCA can help the interventionist plan the PCI,...

Fawaz Bardooli

Author

Fawaz Bardooli
Tajammul Hussain Hakimuddin

Author

Tajammul Hussain Hakimuddin
Precision PCI in the era of AI and multimodality imaging

Complicated subendothelial dissection during left anterior descending coronary artery – first diagonal branch bifurcation treatment with Culotte technique

06 Jan 2025

Learn more about troubleshooting and tailor-made treatment combining 2D and 3D OCT thanks to this image in cardiology!

Troubleshooting of a complicated subendothelial dissection using 2D and 3D OCT

Stepwise OCT for treatment optimization in provisional approach of bifurcated coronary lesions

10 Jan 2025

OCT provides information of the accuracy of every maneuver performed during the treatment of bifurcation lesions. We can clearly see if the POT achieves proximal stent apposition, if the side branch wire crosses through the correct cell, and the impact of final kissing-balloon inflation on stent geometry.

Javier Suarez de Lezo

Author

Javier Suarez de Lezo
Stepwise OCT for treatment optimization in provisional approach of bifurcated coronary lesions