Advancing mitral care with the Intrepid TMVR system

Sponsored by Medtronic

Anchorperson: T. Modine

Spokesperson: A. Duncan

Summary

This EuroPCR 2026 session explores the Intrepid transcatheter mitral valve replacement (TMVR) system and its role in expanding treatment options for patients with mitral regurgitation, including complex anatomies such as mitral annular calcification (MAC).

It highlights how the system’s design features and procedural imaging support a streamlined TMVR approach, alongside practical considerations related to the integration of the 29Fr delivery system. The ongoing clinical research programme is also reviewed, with a focus on emerging evidence and long-term durability data.

Real-world cases from the APOLLO-EU experience illustrate the practical application of the Intrepid system, including challenging MAC scenarios, and provide insight into procedural planning and outcomes in contemporary TMVR practice.

Learning Objectives

To understand how the Intrepid TMVR system streamlines the treatment of mitral regurgitation, especially in mitral annular calcification patients
To learn more about the ongoing Intrepid TMVR clinical research programme
To appreciate the long-term durability of the Intrepid TMVR system