Thomas Modine

Thomas Modine

Cardiac surgeon
Chu De Bordeaux - Haut-Lévêque - Bordeaux, France

Latest contributions

Real world practice inspiring new evidence generation in structural heart

21 May 2026 – From EuroPCR 2026

This LIVE case session showcases real-world clinical practice driving new evidence in structural heart interventions, with a focus on TAVI. It features expert insights into pre-procedural imaging and sizing, treatment strategies, procedural techniques, and post-procedural management. The session also introduces the novel Myval Octapro+ transcatheter heart...

Real world practice inspiring new evidence generation in structural heart

Innovation in transcatheter mitral valve interventions

21 May 2026 – From EuroPCR 2026

This comprehensive session presents the latest innovations in transcatheter mitral valve interventions, highlighting cutting-edge devices and clinical experiences. Topics include early feasibility studies of novel hemivalve systems, first-in-human experiences with new mitral valve replacement technologies, advances in transcatheter edge-to-edge repair (TEER) with one-year outcome data, and...

Combined mitral intervention and LAA closure: LIVE Educational Case from Rigshospitalet Heart Centre - Copenhagen, Denmark

21 May 2026 – From EuroPCR 2026

This session offers a comprehensive educational experience on combined mitral intervention and LAA closure. It identifies ideal candidates, addresses procedural challenges of performing both interventions in a single session, and provides a detailed, step-by-step guide through a live case from Rigshospitalet Heart Centre.

AI adoption in the cathlab of tomorrow - Intravascular imaging applications

20 May 2026 – From EuroPCR 2026

This session examines the integration of artificial intelligence in intravascular imaging within the cath lab, identifying unmet needs in OCT interpretation, exploring AI's role in enhancing procedural decision-making and trust, and discussing barriers to implementation such as prediction reliability and clinical actionability.

AI adoption in the cathlab of tomorrow - Intravascular imaging applications

Advancing mitral care with the Intrepid TMVR system

20 May 2026 – From EuroPCR 2026

This EuroPCR 2026 session explores the Intrepid transcatheter mitral valve replacement (TMVR) system and its role in expanding treatment options for patients with mitral regurgitation, including complex anatomies such as mitral annular calcification (MAC).

It highlights how the system’s design features and procedural imaging support a streamlined...

Advancing mitral care with the Intrepid TMVR system

AI in imaging & the cathlab - opportunities in procedural planning & guidance

20 May 2026 – From EuroPCR 2026

This session explores the role of artificial intelligence in imaging and the cathlab, emphasizing computer vision applications distinct from language models. It discusses AI's integration into procedural planning and guidance, balancing algorithmic support with physician judgement to enhance interventional cardiology workflows.

AI adoption in the cathlab of tomorrow - Risk prediction applications

20 May 2026 – From EuroPCR 2026

This session delves into the adoption of artificial intelligence in the cath lab, focusing on clinically useful risk prediction models for coronary and structural interventions. It covers advanced AI-guided intravascular imaging, machine learning applications for adverse event prediction, and critical evaluation of model validation and clinical...

Transcatheter mitral interventions: outcomes and new procedural approaches

20 May 2026 – From EuroPCR 2026

This session covers transcatheter mitral interventions, comparing surgical and transcatheter approaches, including TEER and TMVR. It presents clinical outcomes, safety data, and innovative procedural techniques such as transeptal BATMAN to prevent left ventricular outflow tract obstruction during TMVR.

First-in-human studies in cardiovascular devices: from first 10 patients to global innovation — How efficient early studies advance emerging technologies

20 May 2026 – From EuroPCR 2026

Understand the pivotal role of first-in-human studies in advancing cardiovascular device innovation through operational insights from early patient experiences. This session reviews cutting-edge technologies including percutaneous left ventricular assist devices, transcatheter leaflet augmentation, physiology-guided PCI, synchronized diaphragmatic stimulation, pulmonary artery denervation, and perspectives on translating early...

AI for clinical and academic cardiology knowledge work: innovation or academic misconduct ? Literature search, data extraction and responsible use

19 May 2026 – From EuroPCR 2026

This session critically examines the role of artificial intelligence in clinical and academic cardiology, focusing on its application in literature search, evidence synthesis, and report structuring. It discusses responsible AI use, emphasizing the balance between assistance and academic integrity, and features a debate on authorship, transparency,...

Clinical experience with transcatheter tricuspid valve replacement

19 May 2026 – From EuroPCR 2026

This session shares clinical experience with transcatheter tricuspid valve replacement (TTVR) for severe tricuspid regurgitation. It includes outcomes after prior repair, analysis of stent frame geometry as a predictor of leaflet abnormalities, and assessments of functional and quality-of-life improvements with systems such as Evoque and MonarQ....

Transcatheter mitral valve replacement in practice

18 Nov 2025 – From PCR London Valves 2025

This session provides an in-depth overview of transcatheter mitral valve replacement (TMVR) in clinical practice, focusing on patient and anatomical suitability assessments including imaging parameters and risk factors for left ventricular outflow tract obstruction. It covers anatomical preparation techniques such as leaflet modification, prior clip removal,...

Transcatheter mitral valve replacement in practice

From diagnosis to device: decision-making and planning for mitral valve interventions

17 Nov 2025 – From PCR London Valves 2025

This session offers a comprehensive overview of decision-making and procedural planning for transcatheter mitral valve interventions. It emphasizes patient-specific factors, advanced imaging for valve morphology assessment, device selection, and the integration of emerging technologies to tailor optimal treatment strategies for mitral valve disease.

From diagnosis to device: decision-making and planning for mitral valve interventions

Paravalvular leaks and VSD percutaneous closure - Recorded cases

17 Nov 2025 – From PCR London Valves 2025

Recorded case 1: A 56-year-old female with a prior mechanical mitral valve replacement (Star GK, 2018), permanent AF, and normal LV function presented with recurrent HF admissions due to paravalvular leaks. She was treated with implantation of multiple plugs via a transseptal approach using a Destination...

Paravalvular leaks and VSD percutaneous closure - Recorded cases

Featured research - Tricuspid valve intervention: latest advanced insights

17 Nov 2025 – From PCR London Valves 2025

This featured research session delves into advanced insights on tricuspid valve interventions, focusing on the significance of right ventricular function and dimension in patient outcomes. It explores prognostic factors such as right ventricular loading mismatch, innovations like the clover technique in Pascal TEER, myocardial work recovery,...

Featured research - Tricuspid valve intervention: latest advanced insights

Shaping the treatment of mitral regurgitation with the Intrepid transcatheter mitral valve replacement (TMVR) system

17 Nov 2025 – From PCR London Valves 2025

This session presents an in-depth examination of the Intrepid transcatheter mitral valve replacement (TMVR) system, focusing on its role in treating mitral regurgitation. It covers the system's design features, ongoing clinical research, and long-term durability, complemented by detailed analyses of transapical 5-year outcomes and current trial...

Shaping the treatment of mitral regurgitation with the Intrepid transcatheter mitral valve replacement (TMVR) system

Shaping the future: top innovations at PCR London Valves 2025

16 Nov 2025 – From PCR London Valves 2025

Highlighting transformative innovations from PCR London Valves 2025, this session features advanced technologies such as the Luna TMVR with its unique intuitive design, the novel Tripair technology for tricuspid therapy, and insights into right heart remodeling following transcatheter tricuspid valve interventions with the DUO system, showcasing...

The Silk Road of MedTech

16 Nov 2025 – From PCR London Valves 2025

Discover pioneering MedTech innovations along the Silk Road, including novel sheath designs for minimalist TAVR, self-expanding valves for pure aortic regurgitation, automated CT quantification via deep learning, and first-in-man experiences with cutting-edge valvuloplasty and TEER devices.

Rapid fire on ortothopic TTVR

16 Nov 2025 – From PCR London Valves 2025

This rapid-fire session presents an overview of the latest orthotopic transcatheter tricuspid valve replacement (TTVR) devices. It features concise discussions on multiple innovative systems including Evoque, Laplace, VDyne, Topaz, and Cardiovalve, offering insights into their design characteristics and clinical applications in tricuspid valve disease management.

Beyond TAVI

16 Nov 2025 – From PCR London Valves 2025

This session offers a glimpse into cutting-edge structural heart interventions beyond TAVI. It introduces novel devices in early development stages targeting aortic valve stenosis and leaflet modification, discusses strategies to facilitate or defer TAVI, and provides opportunities for engagement with early-stage start-up partners innovating in structural...

Step-by-step TAVI for mixed bicuspid aortic valve disease - LIVE Case

30 Sep 2025 – From PCR Gulf Valves 2025

A 65-year-old female with a history of diabetes and moderate left ventricular dysfunction (LVEF 50%) presented with symptomatic severe bicuspid aortic stenosis associated with moderate-to-severe aortic regurgitation. A 26 mm Sapien Resilia valve was implanted under local anesthesia via femoral artery access, with right radial secondary...

Step-by-step TAVI for mixed bicuspid aortic valve disease - LIVE Case

PCR Gulf Valves 2025 Closing Ceremony

30 Sep 2025 – From PCR Gulf Valves 2025

Join the PCR Gulf Valves 2025 Closing Ceremony to reflect on the advancements and highlights of this year’s sessions dedicated to valvular interventions. This event marks the culmination of comprehensive educational activities, fostering collaboration and innovation in valvular heart disease management within the Gulf region.

PCR Gulf Valves 2025 Closing Ceremony

Most impactful trials in structural heart disease 2024/2025

30 Sep 2025 – From PCR Gulf Valves 2025

Delve into the most impactful structural heart disease trials shaping 2024 and 2025. This session addresses current dilemmas in TAVI, including early intervention and management of small annuli, evaluates evidence for transcatheter mitral and tricuspid valve repair, and identifies evidence gaps relevant to the region, providing...

Most impactful trials in structural heart disease 2024/2025

Mitral transcatheter edge-to-edge repair - LIVE Case

29 Sep 2025 – From PCR Gulf Valves 2025

A 65-year-old female with a history of atrial fibrillation, LAD PCI (2016), ICD implantation (2016), stroke, and insulin-dependent DM, presented with symptomatic severe secondary mitral regurgitation and poor left ventricular function (LVEF 20%). A single MitraClip was implanted under general anesthesia and TEE guidance.

LIVE Educational Case...

Mitral transcatheter edge-to-edge repair - LIVE Case

PCR Gulf Valves 2025 Opening Ceremony

29 Sep 2025 – From PCR Gulf Valves 2025

Join us for the PCR Gulf Valves 2025 Opening Ceremony, marking the commencement of an exceptional congress dedicated to advances in structural heart interventions. This session sets the stage for the latest innovations and expert discussions that will shape the future of valve therapies in the...

PCR Gulf Valves 2025 Opening Ceremony

Tricuspid transcatheter therapies: the game changer

29 Sep 2025 – From PCR Gulf Valves 2025

Explore the evolving landscape of tricuspid transcatheter therapies in this comprehensive session reviewing tricuspid regurgitation etiology, anatomy, and current treatment options. Learn about various transcatheter tricuspid valve intervention devices, their strengths and limitations, and the critical diagnostic and intraprocedural imaging requirements to optimize patient selection and...

Tricuspid transcatheter therapies: the game changer

Mastering tricuspid TEER - LIVE Case

12 Sep 2025 – From PCR Rio Valves 2025

A 77-year-old male with atrial fibrillation and chronic kidney disease presented with symptomatic severe atrial tricuspid regurgitation.He underwent implantation of two TriClip XTW devices (antero-septal and postero-septal) under general anesthesia, guided by transesophageal echocardiography (TEE).

LIVE Educational Case from Bordeaux University Hospital - Bordeaux, France

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Mastering tricuspid TEER - LIVE Case

Precision in mitral TEER

11 Sep 2025 – From PCR Rio Valves 2025

Join this live educational session from Bordeaux University Hospital to gain expert insights into mitral transcatheter edge-to-edge repair (TEER). Explore optimal timing and clinical decision-making for mitral regurgitation treatment, and discover how the PASCAL Precision system enhances procedural precision across diverse mitral anatomies. Witness real-time strategies,...

Precision in mitral TEER: LIVE Educational Case from Bordeaux University Hospital - Bordeaux, France

Introducing the team behind PCR Mitral Focus Group

19 Aug 2025

Together with the Mitral Focus Group members, Co-Directors Philipp Lurz and Thomas Modine will work to align knowledge and collaborate globally to improve care for patients with mitral valve disease.

China experience in TAVI evolution

22 May 2025 – From EuroPCR 2025

This session highlights key innovations and recent research from China in the field of transcatheter aortic valve implantation (TAVI). Leading cardiovascular specialist present new data on pacing strategies, comparing left bundle branch area pacing with traditional right ventricular pacing in TAVI patients. They also explore the use...

China experience in TAVI evolution