Thomas Modine

Thomas Modine

Cardiac surgeon
Chu De Bordeaux - Haut-Lévêque - Bordeaux, France

Latest contributions

Shaping the treatment of mitral regurgitation with the Intrepid transcatheter mitral valve replacement (TMVR) system

17 Nov 2025 – From PCR London Valves 2025

This session presents an in-depth examination of the Intrepid transcatheter mitral valve replacement (TMVR) system, focusing on its role in treating mitral regurgitation. It covers the system's design features, ongoing clinical research, and long-term durability, complemented by detailed analyses of transapical 5-year outcomes and current trial...

Shaping the treatment of mitral regurgitation with the Intrepid transcatheter mitral valve replacement (TMVR) system

Featured research - Tricuspid valve interventions - Part 4

17 Nov 2025 – From PCR London Valves 2025

This featured research session delves into advanced insights on tricuspid valve interventions, focusing on the significance of right ventricular function and dimension in patient outcomes. It explores prognostic factors such as right ventricular loading mismatch, innovations like the clover technique in Pascal TEER, myocardial work recovery,...

From diagnosis to device: decision-making and planning for mitral valve interventions

17 Nov 2025 – From PCR London Valves 2025

This session offers a comprehensive overview of decision-making and procedural planning for transcatheter mitral valve interventions. It emphasizes patient-specific factors, advanced imaging for valve morphology assessment, device selection, and the integration of emerging technologies to tailor optimal treatment strategies for mitral valve disease.

Challenging valve and structural interventions: Recorded Educational Cases from Netcare Sunninghill Hospital - Johannesburg, South Africa

17 Nov 2025 – From PCR London Valves 2025

This session presents recorded educational cases from Netcare Sunninghill Hospital in Johannesburg, South Africa, illustrating challenging valve and structural interventions. These real-world cases offer valuable insights into patient presentations and procedural execution in complex structural heart disease management.

The Silk Road of MedTech

16 Nov 2025 – From PCR London Valves 2025

Discover pioneering MedTech innovations along the Silk Road, including novel sheath designs for minimalist TAVR, self-expanding valves for pure aortic regurgitation, automated CT quantification via deep learning, and first-in-man experiences with cutting-edge valvuloplasty and TEER devices.

Beyond TAVI

16 Nov 2025 – From PCR London Valves 2025

This session offers a glimpse into cutting-edge structural heart interventions beyond TAVI. It introduces novel devices in early development stages targeting aortic valve stenosis and leaflet modification, discusses strategies to facilitate or defer TAVI, and provides opportunities for engagement with early-stage start-up partners innovating in structural...

Shaping the future: top innovations at PCR London Valves 2025

16 Nov 2025 – From PCR London Valves 2025

Highlighting transformative innovations from PCR London Valves 2025, this session features advanced technologies such as the Luna TMVR with its unique intuitive design, the novel Tripair technology for tricuspid therapy, and insights into right heart remodeling following transcatheter tricuspid valve interventions with the DUO system, showcasing...

Rapid fire on ortothopic TTVR

16 Nov 2025 – From PCR London Valves 2025

This rapid-fire session presents an overview of the latest orthotopic transcatheter tricuspid valve replacement (TTVR) devices. It features concise discussions on multiple innovative systems including Evoque, Laplace, VDyne, Topaz, and Cardiovalve, offering insights into their design characteristics and clinical applications in tricuspid valve disease management.

Step-by-step TAVI for mixed bicuspid aortic valve disease - LIVE Case

30 Sep 2025 – From PCR Gulf Valves 2025

A 65-year-old female with a history of diabetes and moderate left ventricular dysfunction (LVEF 50%) presented with symptomatic severe bicuspid aortic stenosis associated with moderate-to-severe aortic regurgitation. A 26 mm Sapien Resilia valve was implanted under local anesthesia via femoral artery access, with right radial secondary...

Step-by-step TAVI for mixed bicuspid aortic valve disease - LIVE Case

Most impactful trials in structural heart disease 2024/2025

30 Sep 2025 – From PCR Gulf Valves 2025

Delve into the most impactful structural heart disease trials shaping 2024 and 2025. This session addresses current dilemmas in TAVI, including early intervention and management of small annuli, evaluates evidence for transcatheter mitral and tricuspid valve repair, and identifies evidence gaps relevant to the region, providing...

Most impactful trials in structural heart disease 2024/2025

PCR Gulf Valves 2025 Closing Ceremony

30 Sep 2025 – From PCR Gulf Valves 2025

Join the PCR Gulf Valves 2025 Closing Ceremony to reflect on the advancements and highlights of this year’s sessions dedicated to valvular interventions. This event marks the culmination of comprehensive educational activities, fostering collaboration and innovation in valvular heart disease management within the Gulf region.

PCR Gulf Valves 2025 Closing Ceremony

Tricuspid transcatheter therapies: the game changer

29 Sep 2025 – From PCR Gulf Valves 2025

Explore the evolving landscape of tricuspid transcatheter therapies in this comprehensive session reviewing tricuspid regurgitation etiology, anatomy, and current treatment options. Learn about various transcatheter tricuspid valve intervention devices, their strengths and limitations, and the critical diagnostic and intraprocedural imaging requirements to optimize patient selection and...

Tricuspid transcatheter therapies: the game changer

PCR Gulf Valves 2025 Opening Ceremony

29 Sep 2025 – From PCR Gulf Valves 2025

Join us for the PCR Gulf Valves 2025 Opening Ceremony, marking the commencement of an exceptional congress dedicated to advances in structural heart interventions. This session sets the stage for the latest innovations and expert discussions that will shape the future of valve therapies in the...

PCR Gulf Valves 2025 Opening Ceremony

Mitral transcatheter edge-to-edge repair - LIVE Case

29 Sep 2025 – From PCR Gulf Valves 2025

A 65-year-old female with a history of atrial fibrillation, LAD PCI (2016), ICD implantation (2016), stroke, and insulin-dependent DM, presented with symptomatic severe secondary mitral regurgitation and poor left ventricular function (LVEF 20%). A single MitraClip was implanted under general anesthesia and TEE guidance.

LIVE Educational Case...

Mitral transcatheter edge-to-edge repair - LIVE Case

Mastering tricuspid TEER - LIVE Case

12 Sep 2025 – From PCR Rio Valves 2025

A 77-year-old male with atrial fibrillation and chronic kidney disease presented with symptomatic severe atrial tricuspid regurgitation.He underwent implantation of two TriClip XTW devices (antero-septal and postero-septal) under general anesthesia, guided by transesophageal echocardiography (TEE).

LIVE Educational Case from Bordeaux University Hospital - Bordeaux, France

Navigate the video...

Mastering tricuspid TEER - LIVE Case

Precision in mitral TEER

11 Sep 2025 – From PCR Rio Valves 2025

Join this live educational session from Bordeaux University Hospital to gain expert insights into mitral transcatheter edge-to-edge repair (TEER). Explore optimal timing and clinical decision-making for mitral regurgitation treatment, and discover how the PASCAL Precision system enhances procedural precision across diverse mitral anatomies. Witness real-time strategies,...

Precision in mitral TEER: LIVE Educational Case from Bordeaux University Hospital - Bordeaux, France

Introducing the team behind PCR Mitral Focus Group

19 Aug 2025

Together with the Mitral Focus Group members, Co-Directors Philipp Lurz and Thomas Modine will work to align knowledge and collaborate globally to improve care for patients with mitral valve disease.

China experience in TAVI evolution

22 May 2025 – From EuroPCR 2025

This session highlights key innovations and recent research from China in the field of transcatheter aortic valve implantation (TAVI). Leading cardiovascular specialist present new data on pacing strategies, comparing left bundle branch area pacing with traditional right ventricular pacing in TAVI patients. They also explore the use...

China experience in TAVI evolution

Tricuspid hotline: new devices

22 May 2025 – From EuroPCR 2025

Discover cutting-edge developments in transcatheter tricuspid valve replacement with new device technologies. Review first-in-human trials, early outcomes from multicenter studies, and innovative designs that promise to advance tricuspid regurgitation treatment.

Tricuspid hotline: new devices

Innovations in TMVR and Intrepid trial updates

21 May 2025 – From EuroPCR 2025

This EuroPCR 2025 session highlights the evolving role of transcatheter mitral valve replacement, focusing on the clinical potential of mitral regurgitation elimination. Get an overview of the current status of the Intrepid TMVR programme, learn about the transition to the 29Fr transfemoral system, and explore how...

Innovations in TMVR and Intrepid trial updates

Tailoring transcatheter mitral therapies: a new era

20 May 2025 – From EuroPCR 2025

This session focuses on the evolving landscape of transcatheter mitral valve therapies. Learn about strategic programme development, patient phenotyping to guide device selection and repair versus replacement decisions, and the latest innovations and approvals in transcatheter mitral valve replacement.

Tailoring transcatheter mitral therapies: a new era

Mitral hotline: new devices

20 May 2025 – From EuroPCR 2025

Stay updated on emerging devices in mitral valve repair and replacement with this session covering novel technologies including transcatheter edge-to-edge repair (TEER), posterior leaflet restoration, transfemoral mitral annuloplasty, and a first-in-human transseptal TMVR system. Clinical trial data and early feasibility experiences provide valuable insights into advancing...

Mitral hotline: new devices

How to tailor transcatheter mitral therapies in 2025? A new era

20 May 2025 – From EuroPCR 2025

In this discussion from EuroPCR 2025, Mayra Guerrero, Thomas Modine, and Philipp Lurz explore the evolving landscape of mitral valve treatment.

While transcatheter edge-to-edge repair (TEER) remains a safe and effective approach, it doesn't suit every patient. Alternatives like transcatheter mitral valve replacement (TMVR), annuloplasty, and NeoChord implantation...

How to tailor transcatheter mitral therapies in 2025? A new era

EuroIntervention Journal: 20 years of excellence

25 Feb 2025

Join the PCR community as we commemorate a big year for EuroIntervention!

In this video, your peers share why they read EuroIntervention and how it impacts their daily practice.

Alessandro Beneduce

Author

Alessandro Beneduce
Baris Bugan

Author

Baris Bugan

Author

Davide Capodanno
Marcus Franz

Author

Marcus Franz
Matthew Hammond-Haley

Author

Matthew Hammond-Haley
Muthanna Abdul Halim

Author

Muthanna Abdul Halim
Juri Iwata

Author

Juri Iwata

Author

Thomas Modine

Author

Ashok Seth
Pannipa Suwannasom

Author

Pannipa Suwannasom
Masanori Yamamoto

Author

Masanori Yamamoto

Advanced imaging in tricuspid TEER - LIVE case

26 Nov 2024 – From PCR London Valves 2024

Watch a LIVE case followed by a recorded case on how to use imaging in tricuspid TEER:

  • A 64-year-old male with a history of CABG and COPD, ICD implantation (2013) mitraclip (2018) and poor LV function (25%), presented a torrential functional tricuspid regurgitation. The operators implanted 2...
Advanced imaging in tricuspid TEER - LIVE case

Transcatheter mitral valve replacement - Are we there yet?

25 Nov 2024 – From PCR London Valves 2024

Are we ready to embrace transcatheter mitral valve replacement (TMVR) as the next big step in mitral interventions? Find out in this must-watch video!

Discover the key anatomical factors that favor TMVR over TEER, get acquainted with cutting-edge TMVR platforms like Tioga, Cephea and Intrepid, and master...

Transcatheter mitral valve replacement - Are we there yet?

Turning your idea into a market-ready device - Innovating Medtech

25 Nov 2024 – From PCR London Valves 2024

Have you ever wondered how an idea evolves into a life-changing medical device? This video takes you through the entire journey from clinical need to market-ready solution, highlighting key opportunities and challenges along the way.

Watch it now to learn how to identify the needs that drive...

Turning your idea into a market-ready device - Innovating Medtech

Voices of innovation: perspectives from the stakeholders

25 Nov 2024 – From PCR London Valves 2024

Curious about how innovation becomes impact? This video is a must-watch! Discover now what drives medical breakthroughs from concept to reality and explore the perspectives of those shaping the future of healthcare.

You’ll gain insights into the challenges innovators face at every stage—breakthrough ideas, market regulation, and...

Voices of innovation: perspectives from the stakeholders

Breaking barriers in tricuspid valve repair

25 Nov 2024 – From PCR London Valves 2024

What’s driving the future of transcatheter tricuspid valve repair (TTVR)? Dive into the latest breakthroughs with this video!

Gain insights into real-world outcomes from TTVR registries, uncover key findings from the TriCLASP study, explore how TriClip TEER reshapes the right heart, learn how pulmonary hypertension influences TTVR...

Breaking barriers in tricuspid valve repair

Innovation for transcatheter tricuspid interventions - LIVE case

24 Nov 2024 – From PCR London Valves 2024

Dive into the world of innovation for transcatheter tricuspid interventions. Discuss the remaining challenges associated with currently available options, capture the central role of imaging guidance, and understand the anatomical selection criteria for transcatheter tricuspid valve replacement. Experience a live case from St. Thomas' Hospital, London,...

Innovation for transcatheter tricuspid interventions