16 Nov 2025
From clinical benefits to cost effectiveness: impact of early intervention in asymptomatic severe AS
Supported by Edwards Lifesciences
Summary
Francesco Saia discusses the clinical benefits of early intervention in asymptomatic severe aortic stenosis with Philippe Généreux and Tiffany Patterson. EARLY TAVR trial and supporting studies showed a reduction in death, stroke, and heart failure compared with surveillance. Economic modelling shows early intervention is cost-effective and even cost-saving across multiple European countries. Clinically, experts emphasise proactive patient detection, early referral, and timely workup to maximise outcomes and prevent rehospitalisation.
This interview was filmed at PCR London Valves 2025: see more videos here.