66 results
Randomised comparison of the polymer-free biolimus-coated BioFreedom stent with the ultrathin strut biodegradable polymer sirolimus-eluting Orsiro stent in an all-comers population treated with PCI: the SORT OUT IX Trial
03 Jul 2020
While investigations testing differences in efficacy and safety between drug-eluting stents according to the characteristics of the coating – durable, bioresorbable, or polymer-free – have shown mixed results, several studies have highlighted the benefit of implanting a device with thinner strut.
Reviewer
Effect of ticagrelor monotherapy vs ticagrelor with aspirin on major bleeding and cardiovascular events in patients with acute coronary syndrome : the TICO randomised clinical trial
02 Jul 2020
The outstanding results of the TICO trial have to be interpreted in light of a number of considerations and the generalisability of its results in other contexts requires further analysis.
Reviewer
Impella versus extracorporeal membrane oxygenation for acute myocardial infarction cardiogenic shock
23 Jun 2020
This study aims at evaluating the difference in baseline characteristics, procedural and clinical outcomes in those receiving Impella or ECMO in the United States in the setting of AMI and CS.
Reviewer
Reviewer
Multi- vs culprit-vessel percutaneous coronary intervention in cardiogenic shock
04 May 2020
This study compares outcomes of patients enrolled in the National Cardiogenic Shock Initiative (NCSI) registry treated using a strategy of MV-PCI vs CV-PCI and examines outcomes in patients treated with early MCS.
Reviewer
Ticagrelor or prasugrel in patients with acute coronary syndromes - ISAR-REACT 5
06 Apr 2020
The objective of the Intracoronary Stenting and Antithrombotic Regimen: Rapid Early Action for Coronary Treatment (ISAR-REACT) 5 trial is to test the hypothesis that the ticagrelor strategy is superior to prasugrel strategy in patients with ACS in a composite clinical outcomes.
Reviewer
Reviewer
Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China
28 Mar 2020
This article explores the association between cardiac injury and mortality in patients with COVID-19.
Reviewer
Long-term follow-up of complete versus lesion-only revascularization in STEMI and multivessel disease
21 Jan 2020
The CvLPRIT trial demonstrated that at one-year MACE (all-cause death, recurrent MI, heart failure and ischaemia driven revascularisation) was significantly lower in the CR group compared to the IRA group with no differences in safety endpoints. In this paper, the authors report the extended follow-up to...
Reviewer
Reviewer
Efficacy and safety of low-dose colchicine after myocardial infarction (COLCOT)
09 Dec 2019
COLCOT was a double-blind RCT, designed to evaluate 0.5 mg oral colchicine daily as compared with placebo in patients within 30 days of acute myocardial infarction.
Reviewer
Reviewer
Ticagrelor alone versus dual antiplatelet therapy from 1 month after drug-eluting coronary stenting
10 Nov 2019
One of the most discussed limitations of GLOBAL-LEADER is the lack of event adjudication so that the rate of MI, bleeding or stent thrombosis between the two groups were unknown. In this study, events were adjudicated in those patients from the 20 top-enrolling participating sites.
Reviewer
Effect of P2Y12 inhibitor monotherapy vs dual antiplatelet therapy on cardiovascular events in patients undergoing percutaneous coronary intervention
09 Jul 2019
Results of the SMART-CHOICE randomized clinical trial
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