PCR Journal Club

The HOST-EXAM trial1 was a prospective, randomised, open-label trial investigating clopidogrel monotherapy versus aspirin therapy in patients undergoing PCI with DES who had completed 6-18 months of DAPT with no ischaemic or bleeding complications. At 24 months follow-up, clopidogrel monotherapy significantly reduced the risk of the...

Optical Coherence Tomography fractional flow reserve (OCT-FFR) has been shown to correlate well with wire-based FFR; however, clinical outcomes based on OCT-FFR are not well defined. In this retrospective study, the authors sought to investigate the relationship between OCT-FFR and long-term clinical outcomes in ACS. 

The HOST-REDUCE-POLYTECH-ACS trial was a randomised, parallel-group multicentre trial with a 2x2 factorial design testing two independent hypotheses, one of which was the non-inferiority of durable polymer drug-eluting stents (DP-DES) to biodegradable polymer drug-eluting stents (BP-DES) in patients with ACS. In this post-hoc analysis, the authors...

The ST-OHCA study is a single centre prospective study investigating the incidence, timing and predictors of definite stent thrombosis in comatose survivors of out-of-hospital cardiac arrest (OHCA) undergoing immediate PCI and therapeutic hypothermia.

In this paper, the authors investigated the comparative efficacy and safety of TRA versus TFA in ACS patients undergoing complex PCI in the Minimizing Adverse Haemorrhagic Events by TRansradial Access Site and Systemic Implementation of angioX (MATRIX)-Access trial1.

The results of this study show that at 2-year follow-up HBR patients undergoing PCI with a polymer-based zotarolimus-eluting stent & 1-month DAPT had similar outcomes in terms of both safety & efficacy to those with a polymer-free biolimus A9-coated stent.

The purpose of the current study was to evaluate the impact of performing immediate CAG post-OHCA with stratification of predicted neurologic injury and cardiogenic shock on arrival to a center.

The aim of the current study was to investigate the effects of rivaroxaban on left ventricle thromboprophylaxis in patients with anterior STEMI.

This is an interesting study showing that in patients with STEMI with early infarct artery patency, OCT guidance compared with angiographic guidance of reperfusion was associated with less stent implantation during primary PCI.

This current study explored the effect of heavy particle pollution on total cardiovascular admissions, whilst also looking at risk for specific cardiovascular diagnoses, such as angina, myocardial infarction, and ischaemic stroke.