PCR Journal Club

In the absence of randomized trials to study TAVR in bicuspid arotic stenosis in low-risk patients, prospective cohort studies such as Low-Risk TAVR provide us with valuable information.

Valve-in-valve transcatheter aortic valve implantation (VIV TAVI) over the last few years has been regarded as a reasonable treatment option for patients with failed surgical bioprostheses who are at increased risk for surgical reoperation and suitable anatomical features. While VIV TAVI showed good short-term hemodynamic and...

This study reports the results of using the Left ventricular (LV) guidewire for pacing instead of introducing a temporary RV pacing wire. The safety of this approach is weighed against the potential complications of temporary pacing wires that include access and right ventricular perforation.

Concomitant coronary artery disease (CAD) is frequently found in patients with severe aortic stenosis (AS) undergoing treatment with transcatheter aortic valve implantation (TAVI).

The RECOVERY trial sought to compare long-term clinical outcomes of early surgical AVR with conservative care strategy according to the current guidelines in asymptomatic patients with very severe AS.

The GALILEO trial was a randomized, open-label, event-driven, international, multicentre trial comparing two different preventive strategies for thromboembolic complications in patients who underwent successful TAVI and had not established indication for oral anticoagulation.

This study compared the outcomes of TAVR in patients with pure Aortic Stenosis (i.e., without or trivial AR) vs. patients with MAVD (AS associated with mild to moderate or severe AR).

Although multiple studies have demonstrated an early health status benefit with TAVI vs. SAVR , this is the first randomized trial to demonstrate a persistent, albeit modest, health status advantage with TAVI at 6 and 12 months—timepoints at which patients are assumed to have recovered fully...

The results of this study suggest that the use of self-expandable valves could help reduce the incidence of post-procedural PPM after TAVI, especially in the population with large body size...

The GALILEO-4D was a dedicated substudy that sought to evaluate the effect of oral anticoagulation with rivaroxaban on bioprosthetic aortic valve leaflet thickening and motion impairment.