Christopher Cook
Member of the Editorial Team, PCRonline Editorial Board
Declaration of interest
| Function | Company |
|---|---|
| Honorarium | Phillips Healthcare |
Latest contributions
Structural and Valve interventions: EuroPCR 2026 highlights
21 May 2026 – From EuroPCR 2026
Christopher Cook hosts Bernard Prendergast and Nicolas Dumonteil as they discuss their standout moments from the structural track at EuroPCR 2026. Together, they reflect on the evolution of structural interventions showcased throughout the Course, moving beyond TAVI to the growing importance of mitral and tricuspid therapies...
Taking on the tough stuff: TAVI in complex anatomies
21 May 2026 – From EuroPCR 2026
Focused on the challenges of transcatheter aortic valve implantation (TAVI) in complex anatomies, this session addresses optimal strategies for treating bicuspid aortic valve stenosis, managing small annuli and low coronary ostia, and approaches to degenerated surgical valves including bioprosthetic fracture techniques. Case-based discussions elucidate practical solutions...
AI adoption in the cathlab of tomorrow - Intravascular imaging applications
20 May 2026 – From EuroPCR 2026
This session examines the integration of artificial intelligence in intravascular imaging within the cath lab, identifying unmet needs in OCT interpretation, exploring AI's role in enhancing procedural decision-making and trust, and discussing barriers to implementation such as prediction reliability and clinical actionability.
Debate: how will AI change the cardiology landscape in the next five years?
20 May 2026 – From EuroPCR 2026
Delve into the anticipated impact of artificial intelligence on cardiology over the next five years. This session addresses AI's role in reporting, triage, workflow optimization, and decision-making, while distinguishing realistic clinical benefits from hype. It also discusses governance, accountability, and legal considerations surrounding AI adoption in...
How can we improve the management of aortic stenosis in 2026?
19 May 2026 – From EuroPCR 2026
As aortic stenosis management continues to evolve, this EuroPCR 2026 session looks ahead to the challenges and opportunities shaping clinical practice in 2026. From implementing the latest guidelines in daily care to refining the timing of intervention, the discussion focuses on how earlier identification and treatment...
Managing difficult TAVI scenarios
19 May 2026 – From EuroPCR 2026
Focused on complex TAVI cases, this session reviews guideline recommendations for TAVI in younger patients, strategies for managing concomitant coronary artery disease, and considerations for treating asymptomatic severe aortic stenosis. Real-world cases illustrate clinical decision-making and outcomes.
TAVI: Opening LIVE Educational Case from Clinique Pasteur - Toulouse, France
19 May 2026 – From EuroPCR 2026
This live educational case from Clinique Pasteur in Toulouse, France, focuses on optimal management of coronary artery disease (CAD) in patients undergoing TAVI. The session reviews patient imaging, operator strategies, procedural execution, and key learnings from complex CAD scenarios impacting TAVI outcomes.
TAV in TAVI with coronary protection - LIVE Case
18 Nov 2025 – From PCR London Valves 2025
Watch a LIVE case followed by a recorded case, regarding a 78-year-old female, with a previous TAVI in 2014 (Sapien 3 26) and sarcoidosis, who presented with symptomatic TAVI stenosis. There was a mis-commissural alignment, with the neoskirt plane above the coronary plane. Under general anesthesia,...
TAVI in 2025: transforming care with the new valvular heart disease guidelines
18 Nov 2025 – From PCR London Valves 2025
This session explores how the 2025 valvular heart disease guidelines are transforming the landscape of TAVI care and clinical decision-making. It highlights the paradigm shift in managing severe aortic stenosis and provides a global perspective on the challenges and strategies for managing an expanding TAVI patient...
Prevention and management of TAVI complications
17 Nov 2025 – From PCR London Valves 2025
This session is dedicated to the prevention and management of complications associated with transcatheter aortic valve implantation (TAVI). Participants gain critical knowledge on managing vascular access challenges, anticipating and preventing valve malposition, handling device embolism, and evaluating coronary obstruction risks with effective prevention and bailout strategies.
Aortic valve: PCR London Valves 2025 highlights
17 Nov 2025 – From PCR London Valves 2025
At PCR London Valves 2025, Chris Cook speaks with Course Directors Bernard Prendergast and Simon Redwood about the main highlights from the aortic track. They underline the growing focus on lifetime management, including valve choice, future coronary access, durability, and new long-term data supporting TAVI in...
Latest learnings on the treatment of asymptomatic severe aortic stenosis from the EARLY TAVR
22 May 2025 – From EuroPCR 2025
At EuroPCR 2025, Christopher Cook, Philippe Genereux, and Victoria Delgado discuss key results from the EARLY TAVR study.
In asymptomatic patients with severe aortic stenosis, early intervention was associated with significantly less cardiac damage at 2 years, compared to a surveillance strategy that led to extensive damage...
Structural and Valvular Interventions: EuroPCR 2025 highlights
22 May 2025 – From EuroPCR 2025
Christopher Cook, Nicolas Dumonteil, and Bernard Prendergast share their top EuroPCR 2025 highlights in structural heart interventions. Challenging cases like re-do TAVI, coronary re-access difficulties, and leaflet modification took center stage in case-based and LIVE sessions. Cutting-edge research was featured too, including a meta-analysis combining the...
Complex PCI in a TAVI patient - LIVE case
20 May 2025 – From EuroPCR 2025
An 84-year-old patient with a history of ischemic stroke in 2017, hypertension, diabetes, dyslipidemia, and a preserved LV function (63 %) presented with a severe symptomatic aortic stenosis. The coronary angiography revealed a severe and calcified stenosis of the distal left main.
Operators implanted an Edwards Sapien...
TAVI in patients with a small annulus
20 May 2025 – From EuroPCR 2025
Address the unique challenges of transcatheter aortic valve implantation (TAVI) in patients with small aortic annuli. This session discusses comparative outcomes of balloon-expandable versus self-expandable valves, size prediction methodologies, and management of paravalvular regurgitation in low-flow, low-gradient aortic stenosis cases.
Clinical impact of TAVI frame under-expansion and optimisation strategies
07 Mar 2025
Watch this replay with C. Cook, M. Grygier, A. Khokhar and W-K. Kim to learn about the clinical importance of TAVI frame under-expansion, and so much more!
Heart to Heart Conversations podcasts – expert insights in interventional cardiology, anytime, anywhere
06 Feb 2025
Stay ahead in interventional cardiology with Heart-to-heart podcasts, the audio companion to our acclaimed webinar series.
Focus on Fundamentals in TAVI and mitral - PCR London Valves 2024
Christopher Cook interviews Nicole Karam about the Fundamentals Course, a key component of the PCR London Valves programme that continues to expand each year. Designed for beginners in TAVI or mitral interventions, the course guides participants through every step of a procedure, starting with the basics...
How to improve TAVI durability - LIVE case
26 Nov 2024 – From PCR London Valves 2024
Explore two fascinating cases tackling severe aortic valve challenges with innovative approaches:
- LIVE Case: An 84-year-old woman with a history of breast cancer and TAVI (Evolut Pro 29) in 2016, presenting with symptomatic severe TAVI stenosis. CT revealed a true ID of 19 mm. The team implanted...
Tricuspid valve disease: PCR London Valves 2024 highlights
26 Nov 2024 – From PCR London Valves 2024
Nicolo Piazza and Fabien Praz join Christopher Cook to highlight the key takeaways from the latest presentations on the tricuspid valve.They evoke the new research and scientific evidence that will have an impact on clinical practice, the rapidly evolving technical innovations and the challenges facing tricuspid...
Aortic valve: PCR London Valves 2024 highlights
26 Nov 2024 – From PCR London Valves 2024
Chris Cook interviews Hélène Eltchaninoff and Bernard Prendergast to discuss the highlights of PCR London Valves 2024, focusing on aortic valve disease. They explore how groundbreaking research, including the EARLY TAVR and COMPARE TAVI trials, is shaping and transforming clinical practice.
This interview was filmed at PCR...
From index procedure to re-valving with a novel self-expanding valve
25 Nov 2024 – From PCR London Valves 2024
Watch this simulation-based symposium to explore the value of the Index Procedure in achieving optimal outcomes during the initial implant, crucial for preventing paravalvular leak, pacemaker dependency, and ensuring precise commissural alignment for coronary access. Discover how the ACURATE neo2/PRIME offers excellent coronary access with its...
How to establish a mitral TEER programme
24 Nov 2024 – From PCR London Valves 2024
Ready to start your journey toward establishing a mitral TEER programme? This video covers everything you need to know—from understanding the contemporary role of TEER in managing mitral regurgitation to building a Heart Team and referral network.
Learn how to find your first cases, select the right...
TAVI and coronary artery disease
24 Nov 2024 – From PCR London Valves 2024
How does coronary artery disease shape outcomes in TAVI patients, and when should revascularization come into play? This video explores these critical questions, offering a deep dive into the latest evidence and strategies for managing combined aortic stenosis and coronary artery disease.
From understanding revascularization timing to...
TAVI - Step by step
16 May 2024 – From EuroPCR 2024
This interactive session provides a step-by-step guide on performing minimalist TAVI procedures. Attendees will learn how to optimize TAVI for speed and safety, with a deep dive on the safest techniques for large-bore arterial access and vessel closure. Key topics include femoral access, fluoroscopic projections, crossing...
Interventions for valvular disease: Highlights of EuroPCR 2024
16 May 2024 – From EuroPCR 2024
Christopher Cook hosts Nicolas Dumonteil and Bernard Prendergast as they share EuroPCR 2024 insights on valve disease interventions. Nicolas Dumonteil highlights record-breaking abstracts and cases, demonstrating expertise in TAVI, mitral, and tricuspid procedures. Bernard Prendergast emphasizes LIVE cases, especially in complex TAVI scenarios, reflecting everyday practice. Both stress...
NOTION-2: first TAVI vs. SAVR randomised trial in younger low-risk patients with severe tricuspid or bicuspid aortic valve stenosis
15 May 2024 – From EuroPCR 2024
Christopher Cook interviews Ole de Backer about this study he presented at EuroPCR 2024: It provides further data concerning the 1-year outcome of younger AS patients with tricuspid valve anatomy treated with TAVI compared to SAVR. TAVI and SAVR showed similar rates of the primary endpoint...
First report of an IDE pivotal study of a dedicated splitting device during TAVR
15 May 2024 – From EuroPCR 2024
Watch this interview in which Christopher Cook hosts Martin Leon to discuss pivotal study data on the ShortCut dedicated leaflet splitting device. They revisit the unmet clinical need for leaflet splitting during TAVR: transcatheter valve failures, noting that transcatheter valve failures could surpass surgical bioprosthetic valve failures...
The LANDMARK trial: early outcomes of a randomised non-inferiority trial comparing TAVI devices
15 May 2024 – From EuroPCR 2024
In this video, Christopher Cook interviews Patrick Serruys about the late-breaking clinical trial data from the LANDMARK RCT. Patrick Serruys begins by explaining the LANDMARK trial, which compares TAVI devices, and emphasizes the complexity of applying VARC-3 criteria. He highlights that the 30-day outcomes confirm the...
PCR Teaching Assessment Board: innovation in medical education via peer review feedback
15 May 2024 – From EuroPCR 2024
Victoria Jenkins, William Wijns, and Christopher Cook introduce the Teaching Assessment Board, similar to the peer review process in scientific literature. This group provides structured feedback to teachers and participants, inspired by manuscript evaluation methods to enhance educational quality. The aim is to help faculty improve...
