Paolo Denti

Paolo Denti

Cardiac surgeon
Ospedale San Raffaele - Milano, Italy

Latest contributions

Mitral hotline: new devices

20 May 2025 – From EuroPCR 2025

Stay updated on emerging devices in mitral valve repair and replacement with this session covering novel technologies including transcatheter edge-to-edge repair (TEER), posterior leaflet restoration, transfemoral mitral annuloplasty, and a first-in-human transseptal TMVR system. Clinical trial data and early feasibility experiences provide valuable insights into advancing...

Mitral hotline: new devices

Degeneration of TAVI valves: a new target for innovations

19 May 2025 – From EuroPCR 2025

Discover the latest innovations targeting degeneration of TAVI valves, including expert presentations and cutting-edge technologies like The Splitter, an enabler for transcatheter aortic valve-in-valve implantation.

Degeneration of TAVI valves: a new target for innovations

Featured Research - Mitral valve (Part 4)

25 Nov 2024 – From PCR London Valves 2024

Featured Research - Mitral valve (Part 4)

Featured cases - Challenging tricuspid interventions (Part 1)

24 Nov 2024 – From PCR London Valves 2024

Immerse yourself in a captivating collection of featured cases showcasing the latest advances in transcatheter tricuspid valve interventions. Witness groundbreaking techniques, including the first TTVR designed to reduce afterload mismatch, the management of atrial embolization, and the use of intracardiac echocardiography. Explore complex anatomies, failed prior...

Featured cases - Challenging tricuspid interventions (Part 1)

Featured cases - Atrial septal challenges during mitral TEER

24 Nov 2024 – From PCR London Valves 2024

Delve into this session showcasing selected PCR London Valves 2024 Clinical Cases submissions that highlight the complexities and challenges associated with atrial septal issues during mitral TEER procedures. Explore cases involving a bailout strategy to manage acute single leaflet detachment during Mitraclip, navigating a challenging transseptal...

Featured cases - Atrial septal challenges during mitral TEER

Pacemaker lead and the tricuspid valve: navigating challenges for optimal care

16 May 2024 – From EuroPCR 2024

This session focuses on the complex interplay between pacemaker leads and the tricuspid valve, addressing the anatomical interactions, procedural challenges, and alternative pacing strategies. Attendees will gain a better understanding of the impact of pacemaker leads on tricuspid regurgitation, the techniques for lead implantation and extraction,...

Pacemaker lead and the tricuspid valve: navigating challenges for optimal care

TEER for primary mitral regurgitation - LIVE case

15 May 2024 – From EuroPCR 2024

A 76-year-old male, with previous CABG in 2015, hypertension, diabetes, and pulmonary hypertension (WHO2), presented with severe symptomatic primary MR (P3 flail).
The operators implanted 1 MitraClip (XTW) step-by-step, from the transseptal puncture to the closure, guided by TEE echo and under general anaesthesia, via the venous...

Mitral TEER

How to treat my patient with combined mitral and tricuspid valve disease

21 Nov 2023 – From PCR London Valves 2023

Follow the discussion around the case of this 77-year-old patient with hypertension, diabetes, dyslipidemia, already on dialysis twice a week for chronic kidney disease, and with an implantable automatic defibrillator, who presents with permanent atrial fibrillation, and severe secondary mitral and tricuspid regurgitation, and learn more...

How to treat my patient with combined mitral and tricuspid valve disease

Transcatheter mitral valve replacement

20 Nov 2023 – From PCR London Valves 2023

Consult this session for key insights into diverse TMVR challenges: discover unique scenarios such as para-holes post-Tendyne implant, TMVR in a patient with severe mitral annular calcification, a complex case involving mitral para-ring leak and stenosis with a two-step treatment and an atypical LAMPOON indication, and more!

Transcatheter mitral valve replacement

Transcatheter mitral valve replacement - The wait will be worth it

20 Nov 2023 – From PCR London Valves 2023

Reflect on the past decade of Transcatheter Mitral Valve Replacement (TMVR) to uncover technical and clinical challenges and the lessons they've taught. Explore innovative technologies addressing persistent issues, offering solutions and anticipated timelines. Additionally, delve into the present and future trial designs, exploring the evidence required for...

Transcatheter mitral valve replacement - The wait will be worth it

Top Innovations

20 Nov 2023 – From PCR London Valves 2023

Discover the future of cardiac care with these 3 top innovations! ARTERY, revolutionizing structural heart treatment, Vesalius Transfemoral DMR Repair, combining chordal and annular support in one-transfemoral device, and Approxima, a right ventricular reshaping device, offering a fresh perspective on tricuspid regurgitation.

Top Innovations

Prevention and treatment of left ventricular outflow tract obstruction

19 Nov 2023 – From PCR London Valves 2023

Explore intriguing cases in this session and gain a deeper understanding of preventing and managing LVOT obstruction: uncover innovative approaches such as Valve-in-Valve TMVR with Lampoon, learn about the nuances of TMVR after re-section of the anterior leaflet, and more!

Prevention and treatment of left ventricular outflow tract obstruction

Key questions in tricuspid valve intervention - How do I define treatment options according to individual patient anatomy?

19 Nov 2023 – From PCR London Valves 2023

Explore this tricuspid valve-focused session featuring analysis of four clinical cases: Ebstein anomaly, severe and torrential tricuspid regurgitations, and anterior flail-related torrential regurgitation. Gain insights into optimal treatment selection for each scenario, leveraging pre-procedural imaging for informed decision-making.

Key questions in tricuspid valve intervention - How do I define treatment options according to individual patient anatomy?

Shock with valve disease - Part 2

18 May 2023 – From EuroPCR 2023

In these slides, explore complex scenarios and complications of valve disease; from severe aortic regurgitatione to combined PCI and TAVI with ECMO support. Witness nightmare TAVI cases, the use of an urgent mitral clip, and many more.

Shock with valve disease - Part 2

Transcatheter mitral valve therapies beyond TEER

17 May 2023 – From EuroPCR 2023

Take a ride into the realm of transcatheter mitral valve therapy, going beyond the limits of TEER. Discover the captivating complexities and innovative strategies in this dynamic field, starting with a compelling initial case: transcatheter mitral valve replacement (TMVR) utilizing a semi-rigid flexible three-dimensional annuloplasty ring.

Transcatheter mitral valve therapies

ACS: when a CABG is involved

16 May 2023 – From EuroPCR 2023

Managing ACS in patients who have previously undergone Coronary Artery Bypass Grafting surgery requires careful consideration of their medical history, previous surgical procedures, and potential challenges posed by the surgical alterations. Elevate your comprehension of their management by observing an extensive collection of illustrative scenarios faced...

ACS: when a CABG is involved

Mitral edge-to-edge repair: surgical and transcatheter approaches - LIVE case

29 Nov 2022 – From PCR London Valves 2022

Learn from these 2 cases of primary mitral repair using percutaneous and surgical approaches:

  1. LIVE case - A 90-year-old male with history of LAD PCI 23 years ago and paroxysmal atrial fibrillation presents a primary mitral regurgitation (P2 prolapse) on mildly dilated LV and preserved LV function.
    The operators...
Mitral edge-to-edge repair: surgical and transcatheter approaches

Complex scenarios during mitral valve-in-valve, valve-in-ring or valve-in-MAC procedures - a case-based approach

29 Nov 2022 – From PCR London Valves 2022

Discover some complex scenarios during mitral valve-in-valve, valve-in-ring or valve-in-MAC procedures with these presentations, and learn more about the essential role of TOE and CT imaging in predicting procedural complexity, the pre-emptive techniques and strategies to avoid left ventricular outflow tract obstruction as well as the bailout emergency techniques when...

Complex scenarios during mitral valve-in-valve, valve-in-ring or valve-in-MAC procedures - a case-based approach

Transcatheter mitral valve interventions: clinical outcomes 1

28 Nov 2022 – From PCR London Valves 2022

Consult this session on transcatheter mitral valve interventions to discover a selection of abstracts submitted during PCR London Valves 2022: one-year outcomes for transcatheter mitral repair from the MiCLASP study, the Edwards PASCAL transcatheter mitral valve repair system study, one-year outcomes of Tendyne TMVR treating symptomatic MR,...

Transcatheter mitral valve interventions: clinical outcomes 1

Repair vs. replacement for the treatment of tricuspid valve disease

27 Nov 2022 – From PCR London Valves 2022

Watch this session on tricuspid valve disease to learn more about its current modes of treatment (including new and emerging devices), to understand which patients are the best candidates for this procedure and to explore the challenges that may be encountered during it.

Repair vs. replacement for the treatment of tricuspid valve disease

CLASP II TR, TriBAND, bRIGHT: Late-Breaking Trials on tricuspid intervention

27 Nov 2022 – From PCR London Valves 2022

Discover a selection of PCR London Valves 2022 Late-Breaking Trial submissions in this session: the CLASP II TR on transcatheter tricuspid valve repair, the TriBAND study one-year outcomes on transcatheter tricuspid annular reduction, and the bRIGHT trial on real-world outcomes for TEER.

Tricuspid - Late-Breaking Trials

Primary mitral regurgitation: key imaging requirements for diagnosis and procedural planning

27 Nov 2022 – From PCR London Valves 2022

In this session, find out more about the most common types of primary mitral regurgitation and methods for their evaluation, the principal indications for intervention, as well as the available modes of therapy (surgical/transcatheter) and most appropriate choices for individual patients.

Primary mitral regurgitation: key imaging requirements for diagnosis and procedural planning

How can we improve outcomes for our patients with Mitral Regurgitation? - less is more

29 Oct 2020

Watch the replay of this webinar on transcatheter management of mitral and tricuspid regurgitation with Paolo Denti, Edith Lubos, Scott Lim and Fabien Praz.

Transcatheter edge-to-edge repair: treating heart failure and complications

20 May 2022 – From EuroPCR 2022

Watch this session to discover how to use the most commonly performed tricuspid procedure: transcatheter edge-to-edge repair (TEER) by viewing these different cases: severe right heart failure, repeated use of Alfieri's Stitch, MitraClip complication and much more!

Transcatheter edge-to-edge repair: treating heart failure and complications

Streamlined TAVI with Tokyo Live @EuroPCR

19 May 2022 – From EuroPCR 2022

Watch the live case from Milan, Italy, of an 88-year-old female patient with hypertension who was admitted for dyspnoea with discovery of severe aortic stenosis to consider state-of-the-art TAVI.

Streamlined TAVI with Tokyo Live @EuroPCR

From access to closure in transcatheter valve procedures - Optimising patients' outcomes step by step

18 May 2022 – From EUROPCR 2022

Watch this EuroPCR 2022 session to learn the key steps in transcatheter mitral valve repair and transcatheter aortic valve implantation procedures. 
Follow step by step how to optimally access and close venous large bore access sites using suture mediated vessel closure devices, and learn about the key...

Mitral replacement: expanding patient options, even mitral annular calcification!

18 May 2022 – From EUROPCR 2022

The objectives of this session from EuroPCR 2022 are to provide the best pathway for mitral regurgitation management, to learn about early commercial TMVR experience and to discover treatment options for mitral annular calcification patients.

Transcatheter mitral edge intervention

17 May 2022 – From EuroPCR 2022

In this session, watch LIVE from Toulouse, France, an edge-to-edge transcatheter mitral valve repair on an 85-year-old male patient with severe primary mitral regurgitation and III NYHA shortness of breath, history of hypertension, NSTEMI in November 2019 resulting in PCI with DES on proximal and distal LADs,...

Transcatheter mitral edge intervention

EuroPCR 2022 Early experience and registry results in TAVI: Optimize PRO, FORWARD PRO, Neo-Align, and more!

17 May 2022 – From EuroPCR 2022

Find out more about various studies & registries in TAVI! ACURATE neo2 post-procedural hemodynamic outcomes, first real-world results of the JenaValve TAVI system, Optimize PRO study, a next-generation aortic transcatheter heart valve, commissural alignment, and three-year outcomes following TAVI with a self-expanding valve with pericardial wrap.

EuroPCR 2022 Hotlines / Late-Breaking Trials in TAVI: Optimize PRO, FORWARD PRO, Neo-Align, and more!

Tricuspid valve disease: guidelines and beyond

23 Nov 2021 – From PCR London Valves 2021

Watch this PCR London Valves 2021 session to hear about the latest European guidelines on the management of tricuspid valve disease, understand the details behind these guidelines and how they compare with those elsewhere in the world, and, most importantly, find out how Heart Teams can translate...

Tricuspid valve disease: guidelines and beyond