ST-segment elevation myocardial infarction (STEMI)

The ROLLING STONE registry compares intravascular lithotripsy (IVL) and atherectomy (rotational and orbital) for treating heavily calcified coronary arteries, assessing real-world safety and effectiveness in percutaneous coronary interventions (PCI).

The TICO1 and T-PASS2 trials evaluated abbreviated DAPT followed by ticagrelor monotherapy compared to DAPT in patients with ACS undergoing PCI. Both trials demonstrated the safety and efficacy of abbreviated DAPT however, the optimal timing of aspirin discontinuation remains uncertain. This post hoc analysis compares the...

Live updates on a selection of major Late Breaking Clinical Trials of interest in interventional cardiology presented at the American College of Cardiology 2026 Scientific Sessions #ACC26

The TUXEDO-2 trial sought to directly compare prasugrel versus ticagrelor in diabetic patients undergoing percutaneous coronary intervention (PCI), with the aim of clarifying whether the non-inferiority of ticagrelor could be established.

This study represents a prespecified subgroup analysis of the COMPLETE randomised trial, a large, international, randomised controlled study comparing a strategy of complete revascularisation with culprit-only percutaneous coronary intervention (PCI) in patients presenting with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease (MVD).

The present...

The present analysis compared major adverse cardiac events in patients with significant coronary stenosis (FFR ≤ 0.80 or visual stenosis ≥ 90 %) versus those with non-significant stenosis (FFR > 0.80).

This session addresses complex coronary complications through a series of challenging cases including dextrocardia with acute STEMI, fragile coronary anatomy risks, left main complications, and stent-related issues. It provides critical insights into recognizing and managing unexpected procedural challenges to improve patient safety.

This session presents a diverse range of complex coronary interventions, highlighting advanced techniques and strategies. Topics include the use of ECMO support for high-risk PCI and TAVI in cardiogenic shock, innovative approaches in left main interventions, challenging stent optimisation, and management of patients with combined severe...

This session addresses challenging STEMI scenarios with a focus on atypical presentations, complex complications, and advanced management strategies. Through diverse case discussions, it highlights approaches to overcome procedural difficulties, manage large thrombus burdens, and avoid clinical pitfalls in acute STEMI care.

This session presents complex STEMI cases that highlight the challenges of acute coronary syndrome management, including difficult arterial access, balancing reperfusion with embolization risks, and rare complications such as spontaneous coronary artery dissections. It emphasizes nuanced decision-making in high-stakes clinical scenarios.