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CTO (Chronic total occlusion)

Find all the latest content on chronic total occlusion (CTO) published on this website.

Recently we have seen an increase in successful percutaneous coronary interventions (PCI) of CTO in part due to improvements in hardware (guidewires and balloons), the introduction of dedicated devices (microcatheters, channel dilators, dissection-reentry devices) and the elaboration of CTO-specific techniques. To fully grasp CTO today, here you will find here everything that you need to know including the latest devices and techniques as well as advances in imaging, the use of adjunctive pharmacotherapy, vascular access or understanding bleeding risks…

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The effectiveness and safety of a planned investment procedure in high-risk chronic total occlusions - The INVEST CTO single arm study

03 Nov 2025

Kalaivani Mahadevan and Sofia Papadopoulou provide their take on the INVEST CTO trial, presented by Anja Oksnes at TCT 2025, in San Francisco.

Kalaivani Mahadevan

Author

Kalaivani Mahadevan
Sofia Papadopoulou

Author

Sofia Papadopoulou
INVEST-CTO: Single arm study of a planned investment procedure in high-risk CTO PCI

CTO techniques and strategies

11 Oct 2025 – From AICT-AsiaPCR 2025

Explore advanced techniques and strategic approaches in chronic total occlusion (CTO) interventions, including novel methods for severely calcified lesions, bifurcation management, and complex anatomies such as right main CTOs. The session highlights epicardial collateral navigation, device synergy for calcified coronary disease, indigenous perforation techniques, and ultra-low...

The use of adjunct devices in complex PCI

11 Oct 2025 – From AICT-AsiaPCR 2025

This session offers comprehensive education on the use of adjunct devices in complex PCI, focusing on different microcatheter designs and their optimal handling. It includes case-based illustrations demonstrating microcatheter applications, guidance on utilizing pre-shaped angled microcatheters in difficult anatomies, and the pivotal role of extension guide...

The use of adjunct devices in complex PCI

Artificial intelligence and innovations in interventional cardiology

10 Oct 2025 – From AICT-AsiaPCR 2025

Explore the transformative role of artificial intelligence and robotics in interventional cardiology. This session covers big data fundamentals, bridges the gap between emerging technologies and clinical practice, and discusses AI-enhanced decision-making and robotic applications in cardiovascular interventions.

Artificial intelligence and innovations in interventional cardiology

Best Clinical Cases of AICT-AsiaPCR 2025

10 Oct 2025 – From AICT-AsiaPCR 2025

This session showcases the best clinical cases from AICT-AsiaPCR 2025, highlighting complex scenarios such as post-trauma ST-elevations, transcatheter aortic valve implantation complexities, CTO-PCI in high-bleeding-risk patients, and challenging device retrievals. It emphasizes clinical decision-making and innovative interventional techniques in diverse cardiac pathologies.

Innovative imaging and guidance techniques

10 Oct 2025 – From AICT-AsiaPCR 2025

This session delves into innovative imaging and guidance techniques essential for managing complex coronary interventions. It encompasses challenging scenarios such as spontaneous coronary artery dissection, imaging-guided PCI fine-tuning complications, ruptured sinuses, and complex PCI in elderly patients with severe left ventricular dysfunction. The session also addresses...

Coronary interventions: access, devices and outcomes

10 Oct 2025 – From AICT-AsiaPCR 2025

This session delves into the latest developments in coronary interventions, highlighting advances in vascular access techniques, innovative devices, and clinical outcomes. Topics include endothelial progenitor cell dysfunction in restenosis, the efficacy of distal radial artery (DRA) puncture and sheathless catheters in underserved areas, the use of...

NSTEMI, complex ACS and anatomy

10 Oct 2025 – From AICT-AsiaPCR 2025

This session focuses on complex cases involving non-ST elevation myocardial infarction (NSTEMI), acute coronary syndromes (ACS), and challenging coronary anatomy. It presents unique clinical scenarios such as pediatric rescue PCI, management of significant distal lesions with proximal PCI, anatomical variations complicating interventions, mixed cardiovascular disease management,...

Complex coronary challenges and anomalies

10 Oct 2025 – From AICT-AsiaPCR 2025

This session explores complex coronary challenges and anatomical anomalies encountered in clinical practice. Topics include management of thrombus showers from unexpected culprits, ultra-low contrast angioplasty in mesenteric ischemia, advanced bifurcation PCI techniques with IVUS guidance, and troubleshooting difficult stent delivery scenarios in calcified lesions and challenging...

PCR @ TCT 2025 - Get the international perspective!

15 Oct 2025

Thanks to the contribution of a team of interventional cardiologists from around the globe, get the international perspective on Late-breaking Clinical Trials and Science released at TCT 2025 - check out the list below.

PCRonline @ TCT 2025 - get the international perspective!