CTO (Chronic total occlusion)

Latest CTO content in interventional cardiology - research, practice, and education

Recently we have seen an increase in successful percutaneous coronary interventions (PCI) of CTO in part due to improvements in hardware (guidewires and balloons), the introduction of dedicated devices (microcatheters, channel dilators, dissection-reentry devices) and the elaboration of CTO-specific techniques. To fully grasp CTO today, here you will find here everything that you need to know including the latest devices and techniques as well as advances in imaging, the use of adjunctive pharmacotherapy, vascular access or understanding bleeding risks…

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PCR's Got Talent Round 1 - Session 1

19 May 2026 – From EuroPCR 2026

This dynamic session from PCR's Got Talent Round 1 presents a diverse array of cutting-edge research and clinical findings. Topics include the influence of local and systemic inflammation on PCI outcomes, adherence to OCT-guided PCI metrics, comparative guidance strategies using angiography-derived FFR and IVUS, and the...

CTO PCI: technical developments

19 May 2026 – From EuroPCR 2026

This session highlights technical developments in CTO PCI, featuring comparative insights from the ONUBA-CTO study on retrograde versus antegrade approaches, sex-based differences in long-term outcomes, management of balloon-undilatable lesions, the role of virtual reality audiovisual distraction, the impact of core laboratory feedback with OCT, and contemporary...

CTO PCI: how to prevent and manage complications effectively?

19 May 2026 – From EuroPCR 2026

Focused on chronic total occlusion (CTO) PCI, this session highlights the critical importance of procedural planning to minimize complications. Through detailed case analyses of coronary dissection and perforation, it outlines early identification strategies and equips clinicians with essential tools and techniques for effective complication management in...

CTO PCI: how to prevent and manage complications effectively?

The metal-free strategy: shaping the new era of hybrid vessel restoration with DCB and BRS

19 May 2026 – From EuroPCR 2026

This EuroPCR 2026 session explores the emerging metal-free strategy in coronary intervention, combining drug-coated balloons (DCB) and bioresorbable scaffolds (BRS) to support a “leave-nothing-behind” approach to vessel restoration.

It focuses on lesion preparation, scaffold sizing and deployment, and the integration of hybrid therapies to optimise procedural outcomes....

The metal-free strategy: shaping the new era of hybrid vessel restoration with DCB and BRS

Complication management in CTO PCI - Part 1

19 May 2026 – From EuroPCR 2026

This session addresses complication management during chronic total occlusion (CTO) percutaneous coronary interventions. It covers strategies for unexpected coronary complications, managing tamponade without visible perforation, rescue techniques for atherectomy-related perforations, managing dry pericardial tamponade after septal branch perforation, and challenges when retrograde approaches encounter thrombosis in...

New techniques and tips in CTO PCI

19 May 2026 – From EuroPCR 2026

This session presents new techniques and practical tips in chronic total occlusion (CTO) percutaneous coronary intervention (PCI). It covers innovative approaches such as the side-flap technique, simplified antegrade strategies for calcified lesions, and retrograde CTO techniques, providing valuable insights into overcoming challenging occlusions.

CTO track: EuroPCR 2026 highlights

20 May 2026 – From EuroPCR 2026

Thomas Hovasse speaks with Kambis Mashayekhi about the first dedicated CTO track introduced at EuroPCR 2026.

With chronic total occlusion (CTO) interventions increasingly performed, the need for structured education is growing. This trend reflects an ageing patient population, more surgical turndowns, and a rising number of post-CABG cases, leading...

CTO track: EuroPCR 2026 highlights

What does ORBITA CTO tell us about CTO PCI?

18 Jun 2026 – From EuroPCR 2026

Chronic total occlusions (CTOs) remain a key area of uncertainty in interventional cardiology, particularly regarding symptom improvement after PCI.

In this EuroPCR 2026 interview, John Davies and Sarosh Khan discuss the ORBITA CTO trial and its implications for clinical practice.

As the first double-blind, placebo-controlled randomised trial in...

Does CTO PCI Work? Insights from the ORBITA CTO study

A randomized, placebo-controlled trial of chronic total occlusion PCI in stable angina - ORBITA-CTO trial

03 Apr 2026

Kalaivani Mahadevan provides an in-depth analysis of the ORBITA-CTO trial: a first-ever randomised, double-blind, placebo-controlled trial evaluating CTO PCI in stable angina patients.
She also interviewed principal investigators Sarosh Khan and John Davies following the LBCT Scientific Session at ACC.26 in New Orleans and simultaneous publication in...

John Davies

Author

John Davies
Kalaivani Mahadevan

Author

Kalaivani Mahadevan
Sarosh Khan

Author

Sarosh Khan
ORBITA-CTO: Chronic total occlusion PCI in stable angina

PCRonline @ ACC 2026 Scientific Sessions

12 Mar 2026

Live updates on a selection of major Late Breaking Clinical Trials of interest in interventional cardiology presented at the American College of Cardiology 2026 Scientific Sessions #ACC26

PCRonline @ ACC.26 Scientific Sessions