CTO (Chronic total occlusion)

Latest CTO content in interventional cardiology - research, practice, and education

Recently we have seen an increase in successful percutaneous coronary interventions (PCI) of CTO in part due to improvements in hardware (guidewires and balloons), the introduction of dedicated devices (microcatheters, channel dilators, dissection-reentry devices) and the elaboration of CTO-specific techniques. To fully grasp CTO today, here you will find here everything that you need to know including the latest devices and techniques as well as advances in imaging, the use of adjunctive pharmacotherapy, vascular access or understanding bleeding risks…

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CTO PCI: technical developments

19 May 2026 – From EuroPCR 2026

This session highlights technical developments in CTO PCI, featuring comparative insights from the ONUBA-CTO study on retrograde versus antegrade approaches, sex-based differences in long-term outcomes, management of balloon-undilatable lesions, the role of virtual reality audiovisual distraction, the impact of core laboratory feedback with OCT, and contemporary...

Best clinical CTO cases

19 May 2026 – From EuroPCR 2026

This session presents exemplary clinical cases in chronic total occlusion (CTO) PCI, illustrating advanced procedural strategies and complication management. Cases include retrograde CTO-PCI complicated by catheter-induced dissection, expansion of antegrade CTO PCI limits with hybrid approaches, successful combined antegrade and retrograde hydrodynamic contrast recanalisation, and staged...

PCR's Got Talent Round 1 - Session 1

19 May 2026 – From EuroPCR 2026

This dynamic session from PCR's Got Talent Round 1 presents a diverse array of cutting-edge research and clinical findings. Topics include the influence of local and systemic inflammation on PCI outcomes, adherence to OCT-guided PCI metrics, comparative guidance strategies using angiography-derived FFR and IVUS, and the...

CTO PCI: how to prevent and manage complications effectively?

19 May 2026 – From EuroPCR 2026

Focused on chronic total occlusion (CTO) PCI, this session highlights the critical importance of procedural planning to minimize complications. Through detailed case analyses of coronary dissection and perforation, it outlines early identification strategies and equips clinicians with essential tools and techniques for effective complication management in...

CTO track: EuroPCR 2026 highlights

20 May 2026 – From EuroPCR 2026

Thomas Hovasse speaks with Kambis Mashayekhi about the first dedicated CTO track introduced at EuroPCR 2026.

With chronic total occlusion (CTO) interventions increasingly performed, the need for structured education is growing. This trend reflects an ageing patient population, more surgical turndowns, and a rising number of post-CABG cases, leading...

CTO track: EuroPCR 2026 highlights

What does ORBITA CTO tell us about CTO PCI?

20 May 2026 – From EuroPCR 2026

Chronic total occlusions (CTOs) remain a key area of uncertainty in interventional cardiology, particularly regarding symptom improvement after PCI.

In this EuroPCR 2026 interview, John Davies and Sarosh Khan discuss the ORBITA CTO trial and its implications for clinical practice.

As the first double-blind, placebo-controlled randomised trial in...

Does CTO PCI Work? Insights from the ORBITA CTO study

A randomized, placebo-controlled trial of chronic total occlusion PCI in stable angina - ORBITA-CTO trial

03 Apr 2026

Kalaivani Mahadevan provides an in-depth analysis of the ORBITA-CTO trial: a first-ever randomised, double-blind, placebo-controlled trial evaluating CTO PCI in stable angina patients.
She also interviewed principal investigators Sarosh Khan and John Davies following the LBCT Scientific Session at ACC.26 in New Orleans and simultaneous publication in...

John Davies

Author

John Davies
Kalaivani Mahadevan

Author

Kalaivani Mahadevan
Sarosh Khan

Author

Sarosh Khan
ORBITA-CTO: Chronic total occlusion PCI in stable angina

PCRonline @ ACC 2026 Scientific Sessions

12 Mar 2026

Live updates on a selection of major Late Breaking Clinical Trials of interest in interventional cardiology presented at the American College of Cardiology 2026 Scientific Sessions #ACC26

PCRonline @ ACC.26 Scientific Sessions

Coronary Pot Pourri - 2

11 Dec 2025 – From GulfPCR-GIM 2025

This session presents a diverse range of complex coronary interventions, highlighting advanced techniques and strategies. Topics include the use of ECMO support for high-risk PCI and TAVI in cardiogenic shock, innovative approaches in left main interventions, challenging stent optimisation, and management of patients with combined severe...

Coronary Pot Pourri - 2

Challenging CTO Interventions - Part 2

11 Dec 2025 – From GulfPCR-GIM 2025

This session addresses the complexities of chronic total occlusion (CTO) interventions with a collection of challenging cases employing advanced techniques. Topics include IVUS-assisted recanalisation, hybrid approaches incorporating 3D wiring, retrograde interventions after antegrade failure, and management of procedural complications such as vessel rupture. The session also...

Challenging CTO Interventions - Part 2