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Left main and multivessel disease

Find all the latest content on left main and multivessel disease published on this website.

The left main coronary artery provides the primary source of blood flow to the left ventricle. Diseases affecting the left main, by itself or in combination with multivessel disease, place the patient at significant risk for life-threatening cardiovascular events. Treatment requires an understanding of all available tools, devices and techniques, like those employed in invasive imaging and functional assessment, as well as taking into account underlying comorbidities such as diabetes. Advances in imaging techniques, as well as the use of adjunctive pharmacotherapy, vascular access or invasive interventions such as bypass surgery, are important, as are understanding bleeding risks. Use the filters below to access PCRonline resources.

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Left main and multivessel disease

416 results

Durable polymer vs. biodegradable polymer DES in patients with ACS undergoing complex PCI: A post hoc analysis of the HOST-REDUCE-POLYTECH-ACS trial

30 Aug 2022

The HOST-REDUCE-POLYTECH-ACS trial was a randomised, parallel-group multicentre trial with a 2x2 factorial design testing two independent hypotheses, one of which was the non-inferiority of durable polymer drug-eluting stents (DP-DES) to biodegradable polymer drug-eluting stents (BP-DES) in patients with ACS. In this post-hoc analysis, the authors...

Nicola Ryan

Reviewer

Nicola Ryan
A post hoc analysis of the HOST-REDUCE-POLYTECH-ACS trial

FFR-guided PCI optimization directed by high-definition IVUS versus standard of care - the FFR-REACT trial

24 Aug 2022

The primary objective of the study was to assess whether an IVUS-based stent optimization provided an incremental value in terms of vessel-related adverse event occurrence in patients presenting with low post-PCI FFR (<0.90).

Simone Fezzi

Reviewer

Simone Fezzi
M. Pighi

Reviewer

Michele Pighi
FFR-guided PCI optimization directed by high-definition IVUS versus standard of care - the FFR-REACT trial

Everolimus-eluting stents or bypass surgery for mutivessel coronary artery disease: 10-year outcomes of multicenter randomized controlled BEST trial

20 Sep 2022

Nicola Ryan provides her take on the BEST trial which was presented by Jung-Min Ahn at TCT 2022.

It is a randomised, multicentre, non-inferiority trial comparing PCI with second-generation everolimus-eluting stents and CABG in patients with non-left main multivessel coronary artery disease. At two-year follow-up PCI was shown...

Nicola Ryan

Author

Nicola Ryan
10-Year Outcomes of Multicenter Randomized Controlled BEST Trial: Everolimus-Eluting Stents or Bypass Surgery for Mutivessel CAD

PCI of calcified left main – how to do safely?

12 Nov 2019

View this replay of a LIVE Webinar - PCI of calcified left main – how to do safely?, with E. Barbato, C. K. Naber and F. Ribichini.

PCI of calcified left main – how to do safely?

Complex double stent techniques in left main disease

08 Aug 2019

View this replay of a LIVE Webinar - Complex double stent techniques in left main disease, with G. G. Toth, C. K. Naber and M. Noc.

Complex double stent techniques in left main disease

Left main bifurcation PCI – proper use of imaging guidance

09 Sep 2019

View this replay of a LIVE Webinar - Left main bifurcation PCI – proper use of imaging guidance, with E. Barbato, B. De Bruyne and G. G. Toth.

Left main bifurcation PCI – proper use of imaging guidance

Evaluation of the left main stem - imaging & function

10 Oct 2019

View this replay of a LIVE Webinar - Evaluation of the left main stem - imaging & function, with operators E. Barbato, G. G. Toth, G. Guagliumi, A. Chieffo.

Evaluation of the left main stem - imaging & function

Evaluation of the incidence of radial artery occlusion using different introducer sheaths and hemostasis techniques

19 Jul 2022

This retrospective observational study was undertaken in patients referred for transradial coronary angiography (CA) or PCI to assess the impact of sheath sizes and haemostasis techniques on RAO incidence.

Reviewer

Aaysha Cader
Radial versus femoral access in ACS patients undergoing complex PCI is associated with consistent bleeding benefit and no excess of risk

Definitions and standardized endpoints for treatment of coronary bifurcations: Bif-ARC

03 Jun 2022

The current consensus document, which is prepared by the collaboration of the most renowned interventional cardiology societies and academic research organizations, aims to provide standardized definitions for bifurcation lesions.

Reviewer

Ali Nazmi Calik
Definitions and standardized endpoints for treatment of coronary bifurcations: Bif-ARC

What's new in multivessel disease - a closer look on intracoronary guidance

19 May 2022 – From EuroPCR 2022

What's new in multivessel