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Mitral valve replacement and repair

Latest mitral valve replacement and repair content in interventional cardiology - research, practice, and education

Building on the years of experience with TAVI, mitral valve replacement and repair (TMVR) is now beginning to take-off with a vast array of new techniques and options. Certain devices, for instance in mitral repair, are now widely used. To understand this complex field a knowledge and mastery is required covering the latest research, emerging tools, devices and techniques, vascular access; the role of adjunctive pharmacotherapy; imaging techniques such as echocardiography as well as understanding bleeding risks or patient selection. Find out more…

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Mitral valve replacement and repair

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Interventions in shock

17 Nov 2025 – From PCR London Valves 2025

This session addresses critical interventions in cardiogenic shock, highlighting innovative approaches such as combined valve procedures, management of acute functional mitral regurgitation in STEMI, and advanced transcatheter edge-to-edge repair techniques in refractory heart failure. It offers a comprehensive exploration of strategies to navigate complex hemodynamic instability...

Transcatheter mitral valve-in-valve: alternative strategy for optimal alignment

17 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter mitral valve-in-valve procedures, emphasizing alternative strategies for optimal alignment and lifetime management planning. It delves into engineering the landing zone for challenging anatomies, the integration of the LAMPOON procedure in TMVR valve-in-valve cases, and addresses complexities arising from mitral annular calcification.

Transcatheter mitral valve-in-valve: alternative strategy for optimal alignment

Transcatheter mitral valve-in-valve: transcatheter rescue, balloon migration & more

17 Nov 2025 – From PCR London Valves 2025

This session addresses transcatheter mitral valve-in-valve and valve-in-ring interventions in complex clinical contexts. It includes cases of rescue procedures in valvular dysfunction, ECMO-assisted mitral valve-in-ring implantation in severe left ventricular dysfunction, and innovative approaches to mitral ring anatomy challenges, offering practical insights and procedural tips for...

Transcatheter mitral valve-in-valve: transcatheter rescue, balloon migration & more

From diagnosis to device: decision-making and planning for mitral valve interventions

17 Nov 2025 – From PCR London Valves 2025

This session offers a comprehensive overview of decision-making and procedural planning for transcatheter mitral valve interventions. It emphasizes patient-specific factors, advanced imaging for valve morphology assessment, device selection, and the integration of emerging technologies to tailor optimal treatment strategies for mitral valve disease.

From diagnosis to device: decision-making and planning for mitral valve interventions

What are the key considerations for transcatheter mitral paravalvular leak management?

18 Nov 2025 – From PCR London Valves 2025

Nina Wunderlich and Patrick Calvert discuss mitral paravalvular leaks, which are relatively common. Percutaneous closure is now the default approach, and imaging is central to success: detailed pre-procedural assessment, 3D TOE during the procedure, and careful planning of transseptal puncture. 

This interview was filmed at PCR London...

What are the key considerations for transcatheter mitral paravalvular leak management?

TAVI for aortic regurgitation in high surgical risk: outcomes in 700 patients from ALIGN-AR

12 Feb 2026 – From PCR London Valves 2025

Christopher Allen and Raj Makkar sit down to review the ALIGN-AR trial and its implications for treating native aortic regurgitation. 

ALIGN-AR was a pivotal, single-arm, multicenter investigational study designed to evaluate a dedicated transcatheter solution in patients with moderate-to-severe native AR who were considered high risk for...

Outcomes in 700 patients from ALIGN-AR regarding TAVI for AR in high surgical risk

Is iatrogenic atrial septum defect closure a necessary procedure?

17 Nov 2025 – From PCR London Valves 2025

Philipp Lurz and Saibal Kar discuss iatrogenic atrial septal defects from transseptal procedures. Small ones usually close on their own, while large defects causing significant shunting need closure to prevent right heart overload. Some moderate defects may be beneficial by decompressing the left atrium, so closure...

Is iatrogenic atrial septum defect closure a necessary procedure?

What are the key considerations when managing combined mitral and tricuspid regurgitation?

17 Feb 2026 – From PCR London Valves 2025

Fabien Praz and Neil Fam talk about the management of patients with combined mitral and tricuspid regurgitation, who are often elderly with heart failure and multiple comorbidities. Careful assessment—including echocardiography, hemodynamics, and sometimes CT—is crucial to identify the dominant lesion. Surgery is preferred if feasible, but...

What are the key considerations when managing combined mitral and tricuspid regurgitation?

How do we meet the needs of women with heart valve disease?

27 Mar 2026 – From PCR London Valves 2025

In this interview, Ellen Ross and Marta Sitges discuss a recent initiative from Global Heart Hub - a patient association - which examined the realities faced by women living with heart valve disease. They outline the gaps identified, the call to action that followed, and how...

How do we meet the needs of women with heart valve disease?

How are the new ESC/EACTS valvular guidelines going to impact my mitral programme?

17 Nov 2025 – From PCR London Valves 2025

Francesco Maisano interviews Michael Borger, co-chair of the 2025 ESC/EACS valvular heart disease guidelines, on their practical impact. The updated guidelines emphasize earlier intervention in primary mitral regurgitation, especially for asymptomatic patients with risk factors, while surgery remains preferred for low-risk patients. Michael Borger stresses the...

How are the 2025 ESC/EACTS valvular guidelines going to impact my mitral programme?