599 results
What are the key considerations for transcatheter mitral paravalvular leak management?
18 Nov 2025 – From PCR London Valves 2025
Nina Wunderlich and Patrick Calvert discuss mitral paravalvular leaks, which are relatively common. Percutaneous closure is now the default approach, and imaging is central to success: detailed pre-procedural assessment, 3D TOE during the procedure, and careful planning of transseptal puncture.
This interview was filmed at PCR London...
TAVI for aortic regurgitation in high surgical risk: outcomes in 700 patients from ALIGN-AR
12 Feb 2026 – From PCR London Valves 2025
Christopher Allen and Raj Makkar sit down to review the ALIGN-AR trial and its implications for treating native aortic regurgitation.
ALIGN-AR was a pivotal, single-arm, multicenter investigational study designed to evaluate a dedicated transcatheter solution in patients with moderate-to-severe native AR who were considered high risk for...
Is iatrogenic atrial septum defect closure a necessary procedure?
17 Nov 2025 – From PCR London Valves 2025
Philipp Lurz and Saibal Kar discuss iatrogenic atrial septal defects from transseptal procedures. Small ones usually close on their own, while large defects causing significant shunting need closure to prevent right heart overload. Some moderate defects may be beneficial by decompressing the left atrium, so closure...
What are the key considerations when managing combined mitral and tricuspid regurgitation?
17 Feb 2026 – From PCR London Valves 2025
Fabien Praz and Neil Fam talk about the management of patients with combined mitral and tricuspid regurgitation, who are often elderly with heart failure and multiple comorbidities. Careful assessment—including echocardiography, hemodynamics, and sometimes CT—is crucial to identify the dominant lesion. Surgery is preferred if feasible, but...
How do we meet the needs of women with heart valve disease?
17 Nov 2025 – From PCR London Valves 2025
In this interview, Ellen Ross and Marta Sitges discuss a recent initiative from Global Heart Hub - a patient association - which examined the realities faced by women living with heart valve disease. They outline the gaps identified, the call to action that followed, and how...
How are the new ESC/EACTS valvular guidelines going to impact my mitral programme?
17 Nov 2025 – From PCR London Valves 2025
Francesco Maisano interviews Michael Borger, co-chair of the 2025 ESC/EACS valvular heart disease guidelines, on their practical impact. The updated guidelines emphasize earlier intervention in primary mitral regurgitation, especially for asymptomatic patients with risk factors, while surgery remains preferred for low-risk patients. Michael Borger stresses the...
Mitral valve: PCR London Valves 2025 highlights
17 Nov 2025 – From PCR London Valves 2025
Together with Chris Allen, Course Directors Tiffany Patterson and Nina Wunderlich highlight the Mitral programme from PCR London Valves 2025. The Course began with fundamentals, including imaging and step-by-step procedural training, and then focused on complex cases, complications, and hands-on discussions. LIVE cases featured edge-to-edge repair,...
Five-year outcomes following early experience with transapical TMVR
16 Nov 2025 – From PCR London Valves 2025
In this discussion, Christopher Allen and Michael Reardon review the five-year results of an early transapical TMVR system implanted in very high-risk, inoperable patients.
The device showed sustained elimination of mitral regurgitation, with over 80% of patients maintaining trace or no MR at five years and no...
ENCIRCLE 1-year outcomes: Shaping the future of MR treatment with the SAPIEN M3 system
18 Nov 2025 – From PCR London Valves 2025
Fabien Praz talks with Mayra Guerrero and Henryk Dreger about the ENCIRCLE trial on the Sapien M3 transcatheter mitral valve, which shows strong safety, durable MR reduction, and improved symptoms, quality of life, and LV remodelling. High-quality CT and echo are essential for #TMVR, which is...
Featured research: innovative solutions for mitral valve repair and replacement
16 Nov 2025 – From PCR London Valves 2025
This featured research session offers a comprehensive exploration of mitral valve interventions, encompassing electrosurgical device removal techniques, transcatheter mitral valve replacement (TMVR) outcomes, and transcatheter edge-to-edge repair (TEER) in complex clinical contexts such as heart transplantation and acute valve syndromes. It further examines pulmonary artery systolic...
