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Mitral valve replacement and repair

Latest mitral valve replacement and repair content in interventional cardiology - research, practice, and education

Building on the years of experience with TAVI, mitral valve replacement and repair (TMVR) is now beginning to take-off with a vast array of new techniques and options. Certain devices, for instance in mitral repair, are now widely used. To understand this complex field a knowledge and mastery is required covering the latest research, emerging tools, devices and techniques, vascular access; the role of adjunctive pharmacotherapy; imaging techniques such as echocardiography as well as understanding bleeding risks or patient selection. Find out more…

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Mitral valve replacement and repair

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Complex combined transcatheter interventions

18 Nov 2025 – From PCR London Valves 2025

This session addresses complex combined transcatheter interventions for multivalvular heart disease. It covers integrated transcatheter strategies for multiple valve pathologies, solutions for combined severe aortic stenosis and mitral regurgitation with heavy calcification, and approaches to concomitant atrial functional mitral and tricuspid regurgitation. The session also discusses...

Challenging mitral interventions

18 Nov 2025 – From PCR London Valves 2025

This session explores the complexities of mitral interventions, highlighting advancements and challenges in transcatheter mitral valve repair (TMVR). Topics include the benefits of a simplified single-step TMVR approach, the influence of hemodynamic parameters on MitraClip therapy outcomes, strategies for managing persistent pulmonary oedema, and approaches to...

Paravalvular leak closure - Part 4

18 Nov 2025 – From PCR London Valves 2025

This session delves into the complexities of paravalvular leak closure with a focus on challenging scenarios including unusual TAVI complications in the mitral position, management of mega paravalvular leaks using jumbo devices, and strategies when closure itself poses an obstacle. It also covers acute peri-operative aortic...

Transcatheter mitral valve replacement in practice

18 Nov 2025 – From PCR London Valves 2025

This session provides an in-depth overview of transcatheter mitral valve replacement (TMVR) in clinical practice, focusing on patient and anatomical suitability assessments including imaging parameters and risk factors for left ventricular outflow tract obstruction. It covers anatomical preparation techniques such as leaflet modification, prior clip removal,...

Transcatheter mitral valve replacement in practice

Cardiovalve hits the TARGET: advancing transcatheter valve replacement

18 Nov 2025 – From PCR London Valves 2025

This session highlights the features and procedural steps of the next-generation Cardiovalve systems for tricuspid and mitral valve replacement. It reviews interim results from the TARGET study, emphasizing echocardiographic findings and reverse remodeling effects, and discusses best practices for patient selection and the learning pathway to...

Cardiovalve hits the TARGET: advancing transcatheter valve replacement

From GDMT to TEER: management of secondary mitral regurgitation and the timing of transcatheter intervention

18 Nov 2025 – From PCR London Valves 2025

Delve into the comprehensive management of secondary mitral regurgitation, from guideline-directed medical therapy (GDMT) to transcatheter edge-to-edge repair (TEER). This session elucidates the pathophysiology of atrial and ventricular secondary mitral regurgitation, explores optimized heart failure treatments, and reviews the latest evidence on TEER as a therapeutic...

From GDMT to TEER: management of secondary mitral regurgitation and the timing of transcatheter intervention

Featured research - Mitral valve interventions - Part 4

18 Nov 2025 – From PCR London Valves 2025

This research-focused session presents contemporary evidence and clinical outcomes related to mitral valve interventions. It includes data on transapical mitral valve-in-ring implantation from the European Tendyne registry, prognostic utility of CT-derived fatty muscle fraction in mitral TEER, and comparative outcomes between transapical TMVR and mitral TEER....

Unusual structural interventions - Part 2

18 Nov 2025 – From PCR London Valves 2025

This session highlights unusual structural interventions in cardiology, featuring comprehensive CT screening for left atrial appendage closure, management of procedural complications, novel access techniques for balloon aortic valvuloplasty, transcatheter treatment of mitral bioprosthetic valve vegetation, and percutaneous ventricular septal rupture closure success criteria.

Complications of mitral TEER

18 Nov 2025 – From PCR London Valves 2025

This session addresses complications associated with mitral transcatheter edge-to-edge repair (TEER), showcasing innovative bailout methods such as snare-assisted retrieval of undeployed devices, managing leaflet perforations with latest-generation devices, cases of valve-adjacent tears, mechanical support considerations when pumps fail, and the clinical impact of iatrogenic fossa ovalis...

PCR: Collaborative, inclusive and global

15 Nov 2025 – From PCR London Valves 2025

At PCR, collaboration and inclusion are at the heart of everything we do.

Together, we create an environment where expertise is shared, talents complement each other, and diversity becomes a strength. It is this collective spirit that drives interventional cardiology forward and inspires innovation every day.

During PCR London...

PCR: Collaborative, inclusive and global