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Mitral valve replacement and repair

Find all the latest content on mitral valve replacement and repair published on this website.

Building on the years of experience with TAVI, mitral valve replacement and repair is now beginning to take-off with a vast array of new techniques and options. Certain devices, for instance in mitral repair, are now widely used. To understand this complex field a knowledge and mastery is required covering the latest research, emerging tools, devices and techniques, vascular access; the role of adjunctive pharmacotherapy; imaging techniques such as echocardiography as well as understanding bleeding risks or patient selection. Find out more…

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Mitral valve replacement and repair

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M-TEER with Mitraclip Gen5

03 Feb 2026

An 83-year-old female patient with HFrEF due to NICM and a history of arterial hypertension and persistent atrial fibrillation was referred with worsening exertional dyspnea, severe functional mitral regurgitation and moderate tricuspid regurgitation.

How would you treat this patient?

Tobias Kister

Author

Tobias Kister
M-TEER with Mitraclip Gen5

Mixed mitral valve disease in an irradiated chest with eggshell-like left atrium

26 Jan 2026

Managing mixed mitral valve disease is particularly challenging in patients with prior chest irradiation and extensive calcification.

A 40-year-old man presents with severe symptomatic MR, renal impairment, and an unusual eggshell-like left atrium. Imaging reveals complex mitral anatomy and critical constraints for transcatheter therapy.

How would you approach...

Konstantinos Spargias

Author

Konstantinos Spargias
Mixed mitral valve disease in an irradiated chest with eggshell-like left atrium

Severe mitral regurgitation in a patient at high risk for surgery with a suboptimal anatomy for M-TEER: what other options can we find?

04 Feb 2026

A 78-year-old male presents with recurrent hospitalisations for HFpEF and severe degenerative MR. Multimodality imaging reveals fibro-calcific leaflet disease, restricted motion, and a short posterior leaflet, making him a suboptimal candidate for M-TEER and prompting consideration of transcatheter mitral valve replacement. How would you treat?

Author

Federico De Marco
Elena Dipiertro

Author

Elena Dipietro

Author

Matteo Biroli
Severe MR in a high-risk patient with a suboptimal anatomy for M-TEER: what other options can we find?

Abstracts - Part 2

11 Dec 2025 – From GulfPCR-GIM 2025

This session compiles recent clinical abstracts addressing diverse topics in interventional cardiology. Highlights include the HYBRID-CTO approach from a prospective case series, the cardiovascular impact of empagliflozin in type 2 diabetes, off-label use of intravascular lithotripsy for resistant in-stent lesions, and experiences with non-hyperaemic pressure ratios...

Abstracts - Part 2

Innovation and teamwork in structural heart interventions

11 Dec 2025 – From GulfPCR-GIM 2025

This session explores innovations and collaborative approaches in structural heart interventions, focusing on aortic and mitral valve procedures. It addresses procedural indications, challenges, and the evolving roles of non-physician allied professionals. Interactive elements foster knowledge exchange and support the growth of expertise in the structural heart...

Innovation and teamwork in structural heart interventions

PCR London Valves 2025: Best of Social Media Coverage

20 Nov 2025

This year’s coverage was built on innovative formats to support one clear strategy: sharing strong messages and high-quality education through well-prepared, creative content. The #PCRLV social media team was led by Pamela Gatto, and divided into 6 tracks: aortic, mitral, tricuspid, closure, imaging and nursing.

PCR London Valves 2025: Best of Social Media Coverage

Unusual structural interventions - Part 2

18 Nov 2025 – From PCR London Valves 2025

This session highlights unusual structural interventions in cardiology, featuring comprehensive CT screening for left atrial appendage closure, management of procedural complications, novel access techniques for balloon aortic valvuloplasty, transcatheter treatment of mitral bioprosthetic valve vegetation, and percutaneous ventricular septal rupture closure success criteria.

Complications of mitral TEER

18 Nov 2025 – From PCR London Valves 2025

This session addresses complications associated with mitral transcatheter edge-to-edge repair (TEER), showcasing innovative bailout methods such as snare-assisted retrieval of undeployed devices, managing leaflet perforations with latest-generation devices, cases of valve-adjacent tears, mechanical support considerations when pumps fail, and the clinical impact of iatrogenic fossa ovalis...

Featured research - Mitral valve interventions - Part 4

18 Nov 2025 – From PCR London Valves 2025

This research-focused session presents contemporary evidence and clinical outcomes related to mitral valve interventions. It includes data on transapical mitral valve-in-ring implantation from the European Tendyne registry, prognostic utility of CT-derived fatty muscle fraction in mitral TEER, and comparative outcomes between transapical TMVR and mitral TEER....

From GDMT to TEER: management of secondary mitral regurgitation and the timing of transcatheter intervention

18 Nov 2025 – From PCR London Valves 2025

Delve into the comprehensive management of secondary mitral regurgitation, from guideline-directed medical therapy (GDMT) to transcatheter edge-to-edge repair (TEER). This session elucidates the pathophysiology of atrial and ventricular secondary mitral regurgitation, explores optimized heart failure treatments, and reviews the latest evidence on TEER as a therapeutic...

From GDMT to TEER: management of secondary mitral regurgitation and the timing of transcatheter intervention