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First-in-human studies in cardiovascular devices: from first 10 patients to global innovation — How efficient early studies advance emerging technologies

20 May 2026 – From EuroPCR 2026

Understand the pivotal role of first-in-human studies in advancing cardiovascular device innovation through operational insights from early patient experiences. This session reviews cutting-edge technologies including percutaneous left ventricular assist devices, transcatheter leaflet augmentation, physiology-guided PCI, synchronized diaphragmatic stimulation, pulmonary artery denervation, and perspectives on translating early...

Mitral paravalvular leak closure: case-bases strategies

20 May 2026 – From EuroPCR 2026

This session presents case-based strategies for mitral paravalvular leak closure, highlighting complex percutaneous approaches including multivalvular failure management, apical access techniques, and transatrial direct surgical valve-in-MAC procedures. It features challenging clinical scenarios demonstrating innovative solutions for hemolytic leaks and complex paravalvular defects.

Prognostics elements on multivessel disease and coronary artery disease

20 May 2026 – From EuroPCR 2026

This session examines key prognostic elements in multivessel and coronary artery disease, featuring studies on mechanical circulatory support across LDL-C levels, biomarkers impacting periprocedural myocardial infarction, autologous cell therapy outcomes for refractory angina, and novel risk stratification indices. It also addresses prognosis in cancer patients and...

Management of rare clinical scenarios in the cathlab

20 May 2026 – From EuroPCR 2026

This session addresses the management of rare and complex clinical scenarios encountered in the catheterization laboratory. Cases include dyspnea in coronary artery bypass graft patients, aortocoronary dissection management, complications during coronary sinus reducer implantation, coronary artery aneurysms related to IgG4 vasculitis, ibuprofen-induced Kounis syndrome, and challenging...

A randomised trial comparing imaging-guided PCI with Orsiro vs Xience

18 May 2021

Previous clinical trials suggested that ultra-thin strut biodegradable polymer sirolimus-eluting stent (BP-SES) may be associated with lower target lesion failure (TLF) when compared to durable polymer everolimus-eluting stents (DP-EES). However, the possible underlying mechanisms remain unclear. Therefore, the all-comers CASTLE study was designed to assess the...

Authors :

A randomised trial comparing imaging-guided PCI with Orsiro vs Xience

The FLAVOUR Randomized Clinical Trial: Comparison of Fractional Flow Reserve-guided and Intravascular Ultrasound-guided Percutaneous Coronary Intervention in Intermediate Coronary Artery Stenosis

22 Mar 2022

Daniele Giacoppo analyses the main results of the FLAVOUR trial which were presented by Bon-Kwon Koo, from Seoul National University Hospital, South Korea at the American College of Cardiology 2022. 

Daniele Giacoppo

Author

Daniele Giacoppo
The FLAVOUR Randomized Clinical Trial: Comparison of Fractional Flow Reserve-guided and Intravascular Ultrasound-guided Percutaneous Coronary Intervention in Intermediate Coronary Artery Stenosis

Everolimus-eluting stents or bypass surgery for mutivessel coronary artery disease: 10-year outcomes of multicenter randomized controlled BEST trial

20 Sep 2022

Nicola Ryan provides her take on the BEST trial which was presented by Jung-Min Ahn at TCT 2022.

It is a randomised, multicentre, non-inferiority trial comparing PCI with second-generation everolimus-eluting stents and CABG in patients with non-left main multivessel coronary artery disease. At two-year follow-up PCI was shown...

Nicola Ryan

Author

Nicola Ryan
10-Year Outcomes of Multicenter Randomized Controlled BEST Trial: Everolimus-Eluting Stents or Bypass Surgery for Mutivessel CAD
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