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Featured research - TAVI - Part 14

18 Nov 2025 – From PCR London Valves 2025

This featured research session presents pivotal findings on transcatheter aortic valve implantation (TAVI), including 30-day and one-year outcomes from the VANTAGE trial, novel concepts for assessing aortic stenosis severity, and the influence of mitral annular calcification on conduction disturbances. Additional topics cover the role of clinical...

Complex combined transcatheter interventions

18 Nov 2025 – From PCR London Valves 2025

This session addresses complex combined transcatheter interventions for multivalvular heart disease. It covers integrated transcatheter strategies for multiple valve pathologies, solutions for combined severe aortic stenosis and mitral regurgitation with heavy calcification, and approaches to concomitant atrial functional mitral and tricuspid regurgitation. The session also discusses...

TAVI: complex vascular access - Part 3

18 Nov 2025 – From PCR London Valves 2025

This session focuses on managing complex vascular access challenges in TAVI procedures. It includes case discussions on non-crossable aortic valve stenosis, transseptal TAVI for severe aortic regurgitation with porcelain aorta, and percutaneous implantation in patients with unconventional anatomy or conditions like shaggy syndrome. Strategies for severe...

TAVI valve-in-valve - Part 6

18 Nov 2025 – From PCR London Valves 2025

This session explores valve-in-valve TAVI procedures, addressing intricate cases such as triple valve scenarios, planning challenges in TAVI-in-TAVI, and overcoming obstacles in mitral valve-in-valve therapies. It also presents difficult cases involving dysfunctional stentless aortic bioprostheses and acute leaflet rupture during valve replacement, offering practical insights for...

TAVI: alternative access - Part 2

18 Nov 2025 – From PCR London Valves 2025

This session addresses alternative access routes for TAVI in patients with challenging vascular anatomy. Topics include transapical valve-in-valve procedures complicated by severe aortic regurgitation, percutaneous TAVI via the brachiocephalic trunk, and strategies for managing hostile vascular anatomies. Solutions for scenarios where transfemoral TAVI is not feasible...

Challenging mitral interventions

18 Nov 2025 – From PCR London Valves 2025

This session explores the complexities of mitral interventions, highlighting advancements and challenges in transcatheter mitral valve repair (TMVR). Topics include the benefits of a simplified single-step TMVR approach, the influence of hemodynamic parameters on MitraClip therapy outcomes, strategies for managing persistent pulmonary oedema, and approaches to...

TAVI and coronary artery disease - Part 2

18 Nov 2025 – From PCR London Valves 2025

This session focuses on the intersection of transcatheter aortic valve implantation (TAVI) and coronary artery disease, addressing complex clinical scenarios. It covers innovative approaches such as double "chimney" stenting with balloon-expandable TAVI, strategies for high-risk TAVR combined with multivessel PCI, advances in Medtronic Fx+ TAVR technology,...

When the interventional cardiologist meets the surgeon

18 Nov 2025 – From PCR London Valves 2025

This session highlights collaborative approaches between interventional cardiologists and surgeons in complex valve interventions. It includes cases such as transfemoral valve-in-valve TAVI in bio-Bentall patients with chronic aortic dissection, critical decision-making in life-threatening scenarios, the importance of access choice in TMVR, mechanical leaflet modification of failed...

TAV in TAVI with coronary protection - LIVE Case

18 Nov 2025 – From PCR London Valves 2025

Watch a LIVE case followed by a recorded case, regarding a 78-year-old female, with a previous TAVI in 2014 (Sapien 3 26) and sarcoidosis, who presented with symptomatic TAVI stenosis. There was a mis-commissural alignment, with the neoskirt plane above the coronary plane. Under general anesthesia,...

TAV in TAVI with coronary protection -  LIVE Case

Paravalvular leak closure - Part 4

18 Nov 2025 – From PCR London Valves 2025

This session delves into the complexities of paravalvular leak closure with a focus on challenging scenarios including unusual TAVI complications in the mitral position, management of mega paravalvular leaks using jumbo devices, and strategies when closure itself poses an obstacle. It also covers acute peri-operative aortic...

TAVI: nightmare in the cathlab - Cardiac arrest, aortic root rupture & duct occluder

16 Nov 2025 – From PCR London Valves 2025

Explore critical complications encountered during TAVI procedures in this session, which highlights urgent scenarios such as cardiac arrest from calcific leaflet shift, aortic root rupture, and embolisation events. It also covers salvage techniques like TAVR-in-TAVR-in-SAVR in cardiogenic shock and management of acute left main occlusion with...

TAVI: nightmare in the cathlab - Cardiac arrest, aortic root rupture & duct occluder

Late-Breaking Trials in transcatheter mitral, tricuspid and aortic interventions - Part 1

16 Nov 2025 – From PCR London Valves 2025

This session presents pivotal late-breaking trials in transcatheter mitral and aortic valve interventions. Explore one-year outcomes from the AltaValve early feasibility study featuring atrial fixation TMVR, interim results from the TARGET study assessing Cardiovalve for tricuspid regurgitation, five-year data on transapical TMVR, and outcomes of TAVI...

The Top Late-Breaking Trials - Part 1

Challenging mitral TEER: overcoming access limitations and anatomical challenges

16 Nov 2025 – From PCR London Valves 2025

This session delves into the challenges of mitral transcatheter edge-to-edge repair (TEER), focusing on complex cases such as denied access, patch dehiscence-induced regurgitation, and functional mitral regurgitation due to amyloid cardiomyopathy. It also highlights innovative imaging approaches, including the use of transthoracic echocardiography as a rescue...

Challenging mitral TEER: overcoming access limitations and anatomical challenges

Challenging tricuspid TEER

16 Nov 2025 – From PCR London Valves 2025

This session focuses on the intricacies of transcatheter tricuspid edge-to-edge repair (TEER) addressing iatrogenic tricuspid regurgitation, failed surgical valve repair, and approaches for patients unsuitable for valve replacement. It also examines the management of multiple clip detachments and the procedural nuances required to navigate complex tricuspid...

Complex combined interventions

16 Nov 2025 – From PCR London Valves 2025

This session presents complex combined interventions tackling multiple valvular and structural heart challenges simultaneously. It highlights innovative procedural approaches such as the 'super combo' techniques, strategies for managing deteriorative mitral regurgitation post-tricuspid valve replacement, and comprehensive management of torrential tricuspid regurgitation within rheumatic multivalvular disease contexts,...

Hotline - Valvular and structural interventions

16 Nov 2025 – From PCR London Valves 2025

This session presents pivotal advances in valvular and structural heart interventions, covering the SMART-MV trial on mitral valvotomy safety, outcomes of TAVR patients with tricuspid regurgitation undergoing TEER, and the application of the FLOWer embolic protection system across structural heart procedures. Additionally, it explores the impact...

Mitral TEER - LIVE Case

16 Nov 2025 – From PCR London Valves 2025

Watch this live case followed by a recorded case, regarding a 75-year-old male with type 2 DM, permanent AF, and severe LV dysfunction (30%), with a history of RCA PCI one month earlier and three hospitalizations for heart failure, presented with severe secondary mitral and tricuspid...

Mitral TEER - LIVE Case

Valve selection in urgent TAVI: evidence from small annulus studies - Hotline

16 Nov 2025 – From PCR London Valves 2025

This session presents cutting-edge research comparing self-expanding and balloon-expandable valves in urgent and emergent TAVI settings, with a focus on small aortic annuli. It includes data from the NAVULTRA and LANDMARK trials, featuring novel biomimetic balloon-expandable valves and early feasibility studies that shed light on valve...

Hotline - TAVI - Part 2

Hotline - Mitral and tricuspid valvular interventions

16 Nov 2025 – From PCR London Valves 2025

This session delves into innovative mitral and tricuspid valvular interventions, highlighting outcomes with the PASCAL precision system and advances in combined MitraClip and TriClip repairs. It discusses predictors of heart failure hospitalization post-transcatheter tricuspid valve repair (TTVR), coronary CT-based pacemaker implantation prediction, and novel devices aimed...

Shaping the future: top innovations at PCR London Valves 2025

16 Nov 2025 – From PCR London Valves 2025

Highlighting transformative innovations from PCR London Valves 2025, this session features advanced technologies such as the Luna TMVR with its unique intuitive design, the novel Tripair technology for tricuspid therapy, and insights into right heart remodeling following transcatheter tricuspid valve interventions with the DUO system, showcasing...

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