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Challenging mitral TEER: Barlow's disease, fibro-elastic deficiency & abnormal valve morphology

17 Nov 2025 – From PCR London Valves 2025

This session examines the feasibility and technical considerations of mitral transcatheter edge-to-edge repair (TEER) in complex anatomical and pathological scenarios. Topics include applications in Barlow's disease, fibro-elastic deficiency, congenital heart anomalies, Anderson-Fabry disease, and post-cardiac transplantation, providing valuable insights into expanding TEER indications and overcoming anatomical...

Challenging mitral TEER: Barlow's disease, fibro-elastic deficiency & abnormal valve morphology

Tricuspid valve interventions in complex scenarios - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session delves into transcatheter interventions for the tricuspid valve in complex clinical scenarios. It covers techniques for native annular reduction via TEER, management of lead-related regurgitation, challenging cases of torrential regurgitation with device detachment, and innovative methods facilitating valve-in-ring implantation, enhancing procedural efficacy in tricuspid...

Tricuspid interventions: knowns and unknowns

17 Nov 2025 – From PCR London Valves 2025

Explore the evolving landscape of transcatheter tricuspid valve interventions in this session, which presents the latest evidence from registries and randomized trials. Discussions include the new Euro tricuspid regurgitation risk score, clinical controversies, real-world patient scenarios, and insights into optimal medical therapy and device selection to...

Tricuspid interventions: knowns and unknowns

Cardiogenic shock: transcatheter solutions

17 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter solutions for cardiogenic shock, highlighting rescue therapies such as mitral clip intervention in hypertrophic obstructive cardiomyopathy, valve-in-valve TAVI during CPR, and sequential mechanical circulatory support. It presents complex clinical cases illustrating stepwise approaches combining mechanical support and percutaneous valve repair to...

Transcatheter mitral valve-in-valve, valve-in-ring, and valve-in-MAC

17 Nov 2025 – From PCR London Valves 2025

This session provides an expert overview of transcatheter mitral valve-in-valve, valve-in-ring, and valve-in-MAC procedures. It focuses on unique anatomical and technical considerations, advanced imaging and pre-procedural planning methods, and procedural techniques including device selection and sizing, guided by experienced high-volume operators to optimize procedural success.

Transcatheter mitral valve-in-valve, valve-in-ring, and valve-in-MAC

TAVI valve-in-valve - Paravalvular leak management & complex anatomies

17 Nov 2025 – From PCR London Valves 2025

This session explores the complexities of valve-in-valve TAVI procedures, with a focus on managing paravalvular leaks in failed bioprosthetic valves. It covers challenging cases where surgery is not an option, intricate anatomical considerations, differential diagnosis of paravalvular leaks, and strategies for redo TAVI interventions to optimize...

TAVI valve-in-valve - Paravalvular leak management & complex anatomies

Transcatheter mitral valve-in-valve: alternative strategy for optimal alignment

17 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter mitral valve-in-valve procedures, emphasizing alternative strategies for optimal alignment and lifetime management planning. It delves into engineering the landing zone for challenging anatomies, the integration of the LAMPOON procedure in TMVR valve-in-valve cases, and addresses complexities arising from mitral annular calcification.

Transcatheter mitral valve-in-valve: alternative strategy for optimal alignment

TAVI Valve-in-Valve: Managing unexpected anatomical challenges

17 Nov 2025 – From PCR London Valves 2025

This session examines valve-in-valve interventions in TAVI, highlighting management of concomitant left main disease, unique case narratives such as "The Highlander story," and the unpredictability inherent in these procedures. It also reviews successful transfemoral TAV-in-SAV interventions in acute heparin-induced thrombocytopenia and addresses treatment of degenerated sutureless...

TAVI Valve-in-Valve: Managing unexpected anatomical challenges

New transcatheter mitral valve devices

17 Nov 2025 – From PCR London Valves 2025

This session reviews emerging transcatheter mitral valve devices and their clinical applications. Topics include managing recurrent mitral regurgitation with combined ELASTA-Clip and TMVR approaches, TMVR use in elderly patients, surgical perspectives on device selection, multimodal percutaneous strategies for functional mitral regurgitation, and TMVR as a novel...

Paravalvular leak closure - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session is dedicated to paravalvular leak (PVL) closure techniques, featuring percutaneous approaches after surgical valve implantation and TAVI complications such as annulus rupture. It includes advanced management using multiple plugs for long-tunnel mitral PVLs, innovative transformation from pop-up to plug strategies, and transapical approaches following...

Interventions in shock

17 Nov 2025 – From PCR London Valves 2025

This session addresses critical interventions in cardiogenic shock, highlighting innovative approaches such as combined valve procedures, management of acute functional mitral regurgitation in STEMI, and advanced transcatheter edge-to-edge repair techniques in refractory heart failure. It offers a comprehensive exploration of strategies to navigate complex hemodynamic instability...

TAVI for pure aortic regurgitation: different animal, different challenges, different approaches

17 Nov 2025 – From PCR London Valves 2025

This session delves into the unique anatomical and pathophysiological challenges posed by pure aortic regurgitation and their impact on treatment strategies. It reviews clinical outcomes with established and new transcatheter devices, and presents emerging technologies that promise to advance therapeutic options for this distinct patient population.

TAVI for pure aortic regurgitation: different animal, different challenges, different approaches

Unusual structural interventions: infective endocarditis, ventricular septal rupture & hypertrophic obstructive cardiomyopathy

17 Nov 2025 – From PCR London Valves 2025

This session explores unusual structural interventions, focusing on percutaneous solutions for right-sided infective endocarditis, post-myocardial infarction ventricular septal rupture closure, and novel septal reduction techniques for hypertrophic obstructive cardiomyopathy. It presents challenging cases and device selection considerations in complex structural heart disease.

Unusual structural interventions: infective endocarditis, ventricular septal rupture & hypertrophic obstructive cardiomyopathy

Featured research - TAVI: cutting-edge developments

17 Nov 2025 – From PCR London Valves 2025

This featured research session reviews cutting-edge developments in TAVI, addressing challenges and outcomes in young patients with bicuspid aortic valve stenosis, prognostic significance of concomitant valvular disease, and long-term results of prophylactic chimney stenting and prosthetic valve performance in bicuspid stenosis.

Featured research - TAVI: cutting-edge developments

From diagnosis to device: decision-making and planning for mitral valve interventions

17 Nov 2025 – From PCR London Valves 2025

This session offers a comprehensive overview of decision-making and procedural planning for transcatheter mitral valve interventions. It emphasizes patient-specific factors, advanced imaging for valve morphology assessment, device selection, and the integration of emerging technologies to tailor optimal treatment strategies for mitral valve disease.

From diagnosis to device: decision-making and planning for mitral valve interventions

Valve interventions in grown-up congenital heart disease

17 Nov 2025 – From PCR London Valves 2025

This session presents complex valve interventions in patients with grown-up congenital heart disease, showcasing innovative transcatheter approaches including combined TAVI and pulmonary valve implantation in high-risk patients. Cases highlight management strategies in elderly patients with concomitant conditions such as patent ductus arteriosus and severe left ventricular...

Early Career Research Award Final

17 Nov 2025 – From PCR London Valves 2025

Highlighting pioneering research in structural heart interventions, this session presents studies on the impact of transcatheter tricuspid valve replacement (TTVR) on left ventricular geometry and function, myocardial remodeling in aortic stenosis, physiological responses after mitral and tricuspid edge-to-edge repairs, advancing the understanding of device effects on...

Paravalvular leaks and VSD percutaneous closure - Recorded cases

17 Nov 2025 – From PCR London Valves 2025

Recorded case 1: A 56-year-old female with a prior mechanical mitral valve replacement (Star GK, 2018), permanent AF, and normal LV function presented with recurrent HF admissions due to paravalvular leaks. She was treated with implantation of multiple plugs via a transseptal approach using a Destination...

Paravalvular leaks and VSD percutaneous closure - Recorded cases

Leaflet modification techniques: latest acronyms, concepts and best practice

17 Nov 2025 – From PCR London Valves 2025

Gain comprehensive insights into leaflet modification techniques with a focus on the latest acronyms, concepts, and best practices. This session covers step-by-step approaches to transcatheter electrosurgical leaflet modification, including BASILICA, SHORTCUT, and UNICORN, alongside troubleshooting strategies and the innovative SURPLUS surgical technique.

Leaflet modification techniques: latest acronyms, concepts and best practice

TAVI valve-in-valve

16 Nov 2025 – From PCR London Valves 2025

This session presents complex valve-in-valve TAVI cases, illustrating advanced techniques such as valve fracture and snaring in difficult anatomies, approaches for pure aortic regurgitation in degenerated surgical valves, and strategies overcoming challenges in stentless bioprostheses and previous aortic repairs.

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