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MASTER-DAPT: “the MASTER of high-bleeding risk trials”

28 Aug 2021

Marco Valgimigli (Lugano, Switzerland) presented the results of the MASTER DAPT trial on Saturday, August 28, in a Hot Line session of the ESC Congress 2021. Luis G. Ortega-Paz provides his PICOT & SWOT analysis of this study.

Luis Ortega-Paz

Author

Luis Ortega-Paz
ESC Congress 2021 - MASTER-DAPT : “the MASTER of high-bleeding risk trials”

Elixir Medical completes enrollment in BIOADAPTOR randomized controlled trial of Dynamx Coronary Bioadaptor System

15 Feb 2022

EuroPCR 2025 – One-month dual antiplatelet therapy followed by prasugrel monotherapy at a reduced dose: the 4D-ACS randomised trial

21 May 2025

Paris, France, 20-23 May 2025. The EuroPCR Course Directors have selected 3 major late-breaking trials that will be presented for the first time during the 2025 edition of EuroPCR. These trials were selected because of their design, results, and potential to impact practice, among them is the...

EuroPCR 2025 – One-month dual antiplatelet therapy followed by prasugrel monotherapy at a reduced dose: the 4D-ACS randomised trial

MitrAI score: machine learning models to predict mortality at 12, 24, 36 and 48 months in patients with primary and secondary MR treated by TEER

31 Aug 2024

Jonathan Curio provides his take on the MitrAI score study which was presented by Luigi Biasco at ESC Congress 2024 in London.

Jonathan Curio

Author

Jonathan Curio
MitrAI

Simultaneous high-risk PCI and TAVI with hemodynamic support: a stepwise approach using Impella CP SmartAssist

26 Jun 2025

What’s the safest approach when surgical options are off the table? This real-life case shows how complex coronary revascularsation and TAVI were performed in a single session, supported by Impella.

Explore the rationale behind the sequence, the device choices, and the outcome in a high-risk patient with...

Simultaneous high-risk PCI and TAVI with hemodynamic support: a stepwise approach using Impella CP SmartAssist

Surgical left atrial appendage occlusion in VHD without AF: OPINION Trial

03 Sep 2025

Alex Sticchi provides his take on the results of the OPINION trial presented by Yang Wang at the ESC Congress 2025 in Madrid.

Alessandro Sticchi

Author

Alessandro Sticchi
OPINION Trial: 1-year outcomes

Amulet IDE: Amplatzer Amulet left atrial appendage occluder randomised controlled trial

31 Aug 2021

Luigi Biasco reports the best of Dj Lakkireddy (Overland Park, USA)'s presentation of the AMULET IDE trial at the Monday, August 30 Hot Line session of the ESC Congress 2021.

Luigi Biasco

Author

Luigi Biasco
ESC Congress 2021 - Amulet IDE: Amplatzer Amulet left atrial appendage occluder randomised controlled trial

Cardiac Surgery and the COVID-19 outbreak: what does it mean?

25 Mar 2020

A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak has been declared a Public Health Emergency of International Concern by the WHO since January 2020. The rapid, exponential, increase in confirmed cases makes prevention and control of coronavirus disease (COVID-19) extremely critical. Although clinical manifestations of...

Peter Matt

Author

Peter Matt
Prof. Francesco Maisano

Author

Francesco Maisano
Which cardiac operations should be performed ?

RENOVATE-COMPLEX-PCI: Intravascular imaging-guided versus angiography-guided procedural optimization in complex percutaneous coronary intervention

06 Mar 2023

Daniele Giacoppo reports the main results of the RENOVATE-COMPLEX-PCI trial presented by Joo-Yong Hahn, from the Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, in a Late-Breaking Trial session at the American College of Cardiology (ACC) 2023 / World...

Daniele Giacoppo

Author

Daniele Giacoppo
RENOVATE-COMPLEX-PCI: Intravascular imaging-guided versus angiography-guided procedural optimization in complex percutaneous coronary intervention

OPTION – Indobufen or aspirin on top of clopidogrel after coronary drug-eluting stent implantation

08 Nov 2022

Ali Nazmi Calik provides his take on OPTION, which was presented during AHA 2022 in Chicago.

Author

Ali Nazmi Calik
OPTION – Indobufen or aspirin on top of clopidogrel after coronary drug-eluting stent implantation

Future directions of drug-coated balloon angioplasty

06 Feb 2025

Fernando Alfonso and Javier Cuesta discuss the growing role of drug-coated balloons as an alternative to stents in percutaneous coronary interventions. Highlighting advantages like reduced in-stent restenosis, they emphasize the need for robust clinical studies to refine DCB use.

Dr. F. Alfonso

Author

Fernando Alfonso
Javier Cuesta

Author

Javier Cuesta
Future directions of drug-coated balloon angioplasty

Evidence base: A description of the key, so far published, studies in the space of drug coated balloons

23 Jan 2025

Authored by Hector Garcia-Garcia and Jorge Sanz-Sanchez, this article examines pivotal randomized clinical trials on drug-coated balloons in coronary artery disease. It highlights their role in managing in-stent restenosis, de novo small vessel lesions, and large vessel lesions while exploring future directions through ongoing trials.

Author

Hector Garcia-Garcia
Jorge Sanz Sanchez

Author

Jorge Sanz-Sanchez
Evidence base: A description of the key, so far published, studies in the space of drug coated balloons

ILUMIEN IV: OPTIMAL PCI - Optical Coherence Tomography Guided Coronary Stent Implantation Compared with Angiography: A Multicenter Randomized Trial in Percutaneous Coronary Intervention

29 Aug 2023

Claudio Laudani and Daniele Giacoppo report the main results of the ILUMIEN IV trial presented by Ziad Ali, from the St. Francis Hospital, Roslyn, and Clinical Trials Center, Cardiovascular Research Foundation, New York, in a Hot Line session at the European Society of Cardiology congress 2023...

Claudio Laudani

Author

Claudio Laudani
Daniele Giacoppo

Author

Daniele Giacoppo
ILUMIEN IV: OCT versus angiography
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