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First-in-human studies in cardiovascular devices: from first 10 patients to global innovation — How efficient early studies advance emerging technologies

20 May 2026 – From EuroPCR 2026

Understand the pivotal role of first-in-human studies in advancing cardiovascular device innovation through operational insights from early patient experiences. This session reviews cutting-edge technologies including percutaneous left ventricular assist devices, transcatheter leaflet augmentation, physiology-guided PCI, synchronized diaphragmatic stimulation, pulmonary artery denervation, and perspectives on translating early...

Innovation in transcatheter mitral valve interventions

21 May 2026 – From EuroPCR 2026

This comprehensive session presents the latest innovations in transcatheter mitral valve interventions, highlighting cutting-edge devices and clinical experiences. Topics include early feasibility studies of novel hemivalve systems, first-in-human experiences with new mitral valve replacement technologies, advances in transcatheter edge-to-edge repair (TEER) with one-year outcome data, and...

Routine primary PCI: what can go wrong?

21 May 2026 – From EuroPCR 2026

This session offers an in-depth examination of potential complications during routine primary PCI, focusing on prevention and management strategies. Key learning points include understanding no-reflow phenomena, managing STEMI in post-CABG patients, and handling thrombus burden effectively. Real-world cases illustrate decision-making processes and therapeutic approaches to optimize...

Routine primary PCI: what can go wrong?

Mitral paravalvular leak closure: case-bases strategies

20 May 2026 – From EuroPCR 2026

This session presents case-based strategies for mitral paravalvular leak closure, highlighting complex percutaneous approaches including multivalvular failure management, apical access techniques, and transatrial direct surgical valve-in-MAC procedures. It features challenging clinical scenarios demonstrating innovative solutions for hemolytic leaks and complex paravalvular defects.

Insight from recent evidence in coronary artery disease: value of DCB for de novo lesions (SELUTION) and imaging for left main PCI (OPTIMAL)

21 May 2026 – From EuroPCR 2026

This session reviews pivotal recent evidence impacting daily practice in coronary artery disease management. It discusses the role of drug-coated balloons (DCB) for de novo lesions as evaluated in the SELUTION trial and evaluates intracoronary imaging strategies for left main PCI as presented in the OPTIMAL...

Insight from recent evidence in coronary artery disease: value of DCB for de novo lesions (SELUTION) and imaging for left main PCI (OPTIMAL)

The structural bailout playbook: managing complications

21 May 2026 – From EuroPCR 2026

The session presents a practical structural bailout playbook focused on managing complex complications during structural heart interventions. It features challenging cases such as unusual atrial septal defect closure complications, navigation of a displaced patent ductus arteriosus stent in infants, percutaneous closure of mitral paravalvular leaks with...

The structural bailout playbook: managing complications

Revascularisation in patients with multivessel disease and severe left ventricular impairment

21 May 2026 – From EuroPCR 2026

This session focuses on revascularisation strategies for patients with multivessel coronary disease complicated by severe left ventricular impairment. It emphasizes patient selection criteria, the crucial role of the heart team in decision-making, and optimization of percutaneous revascularisation outcomes. The content includes comprehensive case presentations and discussions...

Revascularisation in patients with multivessel disease and severe left ventricular impairment

Advanced heart failure: left ventricular assist device as bridge to optimise guided-directed medical therapy

21 May 2026 – From EuroPCR 2026

This session explores advanced heart failure management with a focus on guided-directed medical therapy and the role of left ventricular assist devices (LVAD) as a bridge to therapy optimization. It discusses clinical, imaging, and biological parameters indicating LVAD use and highlights devices such as the Impella...

Advanced heart failure: left ventricular assist device as bridge to optimise guided-directed medical therapy

Intercostal embolization of a stuck rotational atherectomy burr

02 Mar 2021

An elective right coronary artery PCI was scheduled in an 83-year-old gentleman. Due to the presence of severely diffuse and calcified disease, rotational atherectomy was decided, but the burr got entrapped in the severely calcified and tortuous proximal segment of the artery...

Embolization of a rotational atherectomy burr

GLORIOUS - Efficacy of restrictive versus liberal oxygenation or Exenatide in patients undergoing coronary artery bypass grafting or aortic valve replacement – a randomised clinical trial

21 Nov 2024

Edoardo Zancanaro provides his take on the GLORIOUS trial presented by Sebastian Wiberg at AHA 2024 in Chicago.

Edoardo Zancanaro

Author

Edoardo Zancanaro
GLORIOUS

RESHAPE-HF2 - Percutaneous repair of moderate-to-severe or severe functional mitral regurgitation in patients with symptomatic heart failure

01 Sep 2024

Nicola Ryan provides her take on the RESHAPE-HF2 trial presented by Stefan Anker at the ESC Congress 2024 in London and simultaneously published in the NEJM.

The RESHAPE-HF 2 trial is a prospective randomised control trial comparing transcatheter mitral valve repair (TEER) and guideline-directed medical therapy to guideline-directed medical...

Nicola Ryan

Author

Nicola Ryan
RESHAPE-HF2

TACSI: Dual or single antiplatelet therapy after CABG in patients with acute coronary syndrome

03 Sep 2025

Aaysha Cader provides her take on TACSI presented by Anders Jeppsson at ESC Congress 2025 in Madrid.

Author

Aaysha Cader
TACSI: Dual or single antiplatelet therapy after CABG in patients with acute coronary syndrome

NEO-MINDSET: Early withdrawal of aspirin after percutaneous coronary intervention for acute coronary syndrome

02 Sep 2025

Daniele Giacoppo reports and provides his perspective on the main results of the ambitious NEOMINDSET trial, presented by Pedro Lemos from the Hospital Israelita Albert Einstein, São Paulo, Brazil, during a Late Breaking Trials session at the ESC Congress 2025 in Madrid, and simultaneously published in the New...

Daniele Giacoppo

Author

Daniele Giacoppo
NEO-MINDSET: Early withdrawal of aspirin after percutaneous coronary intervention for acute coronary syndrome
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