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Registries and trials in mitral TEER

20 May 2026 – From EuroPCR 2026

This comprehensive session reviews registries and clinical trials in mitral transcatheter edge-to-edge repair (TEER). It includes discussions on novel TEER systems, international consensus on PASCAL implants, anatomical predictors of procedural success, and long-term outcomes including ventricular and atrial remodeling after intervention, as well as emerging therapies...

AI in imaging & the cathlab - opportunities in procedural planning & guidance

20 May 2026 – From EuroPCR 2026

This session explores the role of artificial intelligence in imaging and the cathlab, emphasizing computer vision applications distinct from language models. It discusses AI's integration into procedural planning and guidance, balancing algorithmic support with physician judgement to enhance interventional cardiology workflows.

Imaging the calcified lesions: what you need to see

20 May 2026 – From EuroPCR 2026

This session emphasizes critical imaging aspects necessary for assessing calcified coronary lesions. It addresses lesion-specific Agatston scoring, OCT-guided PCI optimization, coronary CT planning, histopathological insights, and predictors of stent underexpansion after calcium modification.

Optimal timing of aspirin discontinuation: when early is too early?

20 May 2026 – From EuroPCR 2026

This session critically evaluates the optimal timing for aspirin discontinuation after PCI, discussing outcomes of aspirin-free strategies initiated within one month versus three months post-procedure. It considers differential effects of DAPT duration based on ACS presentation and bleeding risk, supported by meta-analyses and real-world data to...

The PASCAL IID Registry: A prospective registry for transcatheter edge-to-edge repair in prohibitive risk patients with degenerative mitral regurgitation and complex mitral valve anatomy

17 Sep 2022

Alex Sticchi provides his take on the PASCAL IID Registry and an initial comparison with the CLASP IID. The trial was presented by Jörg Hausleiter during TCT Congress 2022.

Alessandro Sticchi

Author

Alessandro Sticchi
The PASCAL IID Registry: A Prospective Registry for Transcatheter Edge-to-Edge Repair in Prohibitive Risk Patients With Degenerative MR and Complex Mitral Valve Anatomy

EuroPCR 2024 – Short-term data from NOTION-2: TAVR versus SAVI for younger patients with aortic stenosis

15 May 2024

Paris, France, 14-17 May 2024. The Course Directors have selected 3 major Late Breaking Trials (LBTs) that were presented for the first time during the 2024 edition of EuroPCR. These trials were selected on account of their design, outcomes and potential to influence daily clinical practice....

Transcatheter edge-to-edge repair of functional mitral regurgitation in heart failure: Final five-year results from the COAPT Trial

06 Mar 2023

Alex Sticchi & Jonathan Curio provide their take on the clinical trial presented by Gregg W. Stone at the American College of Cardiology Scientific Sessions (ACC.23/WCC).

Jonathan Curio

Author

Jonathan Curio
Alessandro Sticchi

Author

Alessandro Sticchi
Transcatheter edge-to-edge repair of functional mitral regurgitation in heart failure: Final five-year results from the COAPT Trial

Controlled ring expansion during aortic valve-in-valve: a proof-of-concept CT-scan analysis

24 Jun 2024

Analyze this EIJ image to see how surgical aortic bioprostheses with expandable ring technology can significantly enhance future ViV procedures.

Controlled ring expansion during aortic valve-in-valve: a proof-of-concept CT-scan analysis

MitrAI score: machine learning models to predict mortality at 12, 24, 36 and 48 months in patients with primary and secondary MR treated by TEER

31 Aug 2024

Jonathan Curio provides his take on the MitrAI score study which was presented by Luigi Biasco at ESC Congress 2024 in London.

Jonathan Curio

Author

Jonathan Curio
MitrAI

The JenaValve Trilogy™ heart valve system in high surgical risk patients with symptomatic, severe aortic regurgitation: The ALIGN AR Trial

25 Oct 2023

Nicola Ryan provides her take on the ALIGN AR trial which was presented by Vinod H. Thourani at TCT Congress 2023. The Align AR trial is a prospective single-arm investigation device exemption study assessing the safety and efficacy of the Trilogy transcatheter heart valve system in patients with...

Nicola Ryan

Author

Nicola Ryan
Initial Outcomes of the JenaValve Trilogy Transcatheter Aortic Valve Replacement System in High-Risk Patients with Symptomatic Severe Native Aortic Regurgitation (ALIGN-AR)

NOTION-3 - Percutaneous coronary intervention in patients undergoing transcatheter aortic valve implantation

01 Sep 2024

Make the most of the insights from Jacob Thomsen Loenborg’s interview with Chiara De Biase and Ali Nazmi Calik’s article to capture the key takeaways from this trial, simultaneously published in the NEJM, presented at the ESC Congress 2024 in London.

Author

Chiara De Biase
Jacob Lønborg

Author

Jacob Lønborg
Ali Nazmi Calik

Author

Ali Nazmi Calik
NOTION 3

Early intervention in patients with asymptomatic severe aortic stenosis and left ventricular myocardial fibrosis (EVOLVED)

30 Oct 2024

Ali Nazmi Calik provides his take on the EVOLVED trial presented by Marc Dweck at TCT 2024 in Washington.

Ali Nazmi Calik

Author

Ali Nazmi Calik
Early intervention in patients with asymptomatic severe aortic stenosis and left ventricular myocardial fibrosis (EVOLVED)

When transfemoral TAVI is not an option: rethinking alternative access strategies

18 Jun 2026

In this article, Ulrich Schäfer explores the evolving landscape of access strategies in transcatheter aortic valve implantation (TAVI). While the transfemoral approach remains the gold standard, a significant proportion of patients are not suitable due to peripheral vascular disease or anatomical constraints.
Drawing on clinical evidence and...

Author

Ulrich Schaefer
Alternative access, if transfemoral is not working
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