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Featured research - Mitral valve interventions: Physiology & device innovation

17 Nov 2025 – From PCR London Valves 2025

This session highlights groundbreaking research on mitral valve interventions featuring advanced transcatheter techniques. Topics include coronary physiology assessment with vFFR in severe mitral regurgitation, predictive versus actual outcomes in TMVR, innovative devices like Epygon and INNOVALVE, and novel approaches such as the ReNiva posterior leaflet replacement...

Featured research - Mitral valve interventions: Physiology & device innovation

Left atrial appendage occlusion

17 Nov 2025 – From PCR London Valves 2025

This session focuses on the complexities and innovations in left atrial appendage occlusion (LAAO) procedures. It covers transesophageal ICE monitoring, challenges posed by existing atrial septal occluders, combined surgical and percutaneous approaches, and the practical experience with the Ultraseal device. These insights advance understanding of procedural...

TAVI: complex vascular access

17 Nov 2025 – From PCR London Valves 2025

This session addresses the challenges of complex vascular access in transcatheter aortic valve implantation (TAVI). It discusses strategies for navigating difficult thoraco-abdominal aortic anatomies, managing double aortic arches, and overcoming hostile femoral access. Case studies illustrate meticulous planning and innovative solutions essential for successful TAVI in...

Mitral TEER and LAA closure - LIVE Case

17 Nov 2025 – From PCR London Valves 2025

Watch a LIVE case followed by a recorded case regarding a 91-year-old female with permanent AF, LAD PCI three months earlier, and recurrent GID bleeding who presented with symptomatic severe primary mitral regurgitation due to P2 prolapse and flail. CT imaging showed a LAA with a...

Mitral TEER and LAA closure -  LIVE Case

TAVI: nightmare in the cathlab - Annular perforation, coronary obstruction & balloon rupture

17 Nov 2025 – From PCR London Valves 2025

This session presents critical case analyses of complicated TAVI procedures, highlighting unexpected and severe intra-procedural events such as annular perforation, leaflet modification complications, coronary obstructions, and device failures. It emphasizes prevention strategies, bailout techniques, and acute management to prepare clinicians for handling TAVI-related emergencies effectively.

TAVI: nightmare in the cathlab - Annular perforation, coronary obstruction & balloon rupture

TAVI in patients with concomitant valve and coronary artery disease

17 Nov 2025 – From PCR London Valves 2025

Focused on patients with concomitant valve and coronary artery disease, this session examines evaluation strategies for aortic stenosis burden, integrates recent trial data on combined TAVI and PCI, and discusses optimal management approaches in complex multi-valve disease scenarios through detailed case presentations and clinical outcomes.

TAVI in patients with concomitant valve and coronary artery disease

Challenging mitral TEER: Barlow's disease, fibro-elastic deficiency & abnormal valve morphology

17 Nov 2025 – From PCR London Valves 2025

This session examines the feasibility and technical considerations of mitral transcatheter edge-to-edge repair (TEER) in complex anatomical and pathological scenarios. Topics include applications in Barlow's disease, fibro-elastic deficiency, congenital heart anomalies, Anderson-Fabry disease, and post-cardiac transplantation, providing valuable insights into expanding TEER indications and overcoming anatomical...

Challenging mitral TEER: Barlow's disease, fibro-elastic deficiency & abnormal valve morphology

Pulmonary valve interventions

17 Nov 2025 – From PCR London Valves 2025

This session presents complex cases and innovative solutions in pulmonary valve interventions. It highlights a novel balloon-expandable valve for the right ventricular outflow tract, management of severe prosthetic pulmonary valve stenosis in congenital heart disease, approaches to residual lesions in Fallot's anomaly, treatment of double outlet...

Pulmonary valve interventions

Interventional management of an aortic root fistula after aortic-valve endocarditis

25 Jan 2021

This is a 44-year old male patient with an aortic root fistula to the right heart after past infective aortic valve endocarditis. Interventional shunt occlusion was successfully performed using a transcatheter closure device.

Interventional aortic root fistula closure

RHEIA - Transcatheter versus surgical aortic valve replacement in women with severe aortic stenosis

01 Sep 2024

While Chiara De Biase interviews Helene Eltchaninoff about the RHEIA trial results, which she presented at the ESC Congress 2024 in London, Panos Xaplanteris shares his perspective on the trial, offering all the essential information and key takeaways you need for your practice!

Author

Chiara De Biase

Author

Helene Eltchaninoff
Panagiotis Xaplanteris

Author

Panagiotis Xaplanteris
RHEIA

The FLAVOUR Randomized Clinical Trial: Comparison of Fractional Flow Reserve-guided and Intravascular Ultrasound-guided Percutaneous Coronary Intervention in Intermediate Coronary Artery Stenosis

22 Mar 2022

Daniele Giacoppo analyses the main results of the FLAVOUR trial which were presented by Bon-Kwon Koo, from Seoul National University Hospital, South Korea at the American College of Cardiology 2022. 

Daniele Giacoppo

Author

Daniele Giacoppo
The FLAVOUR Randomized Clinical Trial: Comparison of Fractional Flow Reserve-guided and Intravascular Ultrasound-guided Percutaneous Coronary Intervention in Intermediate Coronary Artery Stenosis

Everolimus-eluting stents or bypass surgery for mutivessel coronary artery disease: 10-year outcomes of multicenter randomized controlled BEST trial

20 Sep 2022

Nicola Ryan provides her take on the BEST trial which was presented by Jung-Min Ahn at TCT 2022.

It is a randomised, multicentre, non-inferiority trial comparing PCI with second-generation everolimus-eluting stents and CABG in patients with non-left main multivessel coronary artery disease. At two-year follow-up PCI was shown...

Nicola Ryan

Author

Nicola Ryan
10-Year Outcomes of Multicenter Randomized Controlled BEST Trial: Everolimus-Eluting Stents or Bypass Surgery for Mutivessel CAD

TRI.fr trial - Multicentric randomised evaluation of the transcatheter edge-to-edge repair in the treatment of severe isolated secondary tricuspid regurgitation

31 Aug 2024

Alex Sticchi provides his take on the results of the TRI.FR trial presented by Erwan Donal at the ESC Congress 2024 in London.

Alessandro Sticchi

Author

Alessandro Sticchi
Tri.fr trial
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