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Featured research - TAVI - Part 14

18 Nov 2025 – From PCR London Valves 2025

This featured research session presents pivotal findings on transcatheter aortic valve implantation (TAVI), including 30-day and one-year outcomes from the VANTAGE trial, novel concepts for assessing aortic stenosis severity, and the influence of mitral annular calcification on conduction disturbances. Additional topics cover the role of clinical...

Complications of valve-in-valve TAVI

18 Nov 2025 – From PCR London Valves 2025

This session addresses the complex complications associated with valve-in-valve TAVI procedures. Topics include delayed coronary compromise, unexpected clinical scenarios, the importance of recognizing surgical bioprosthesis types, the dual role of calcium in TAVI, and intricate left ventricular complications that can arise post valve-in-valve interventions.

Complex combined transcatheter interventions

18 Nov 2025 – From PCR London Valves 2025

This session addresses complex combined transcatheter interventions for multivalvular heart disease. It covers integrated transcatheter strategies for multiple valve pathologies, solutions for combined severe aortic stenosis and mitral regurgitation with heavy calcification, and approaches to concomitant atrial functional mitral and tricuspid regurgitation. The session also discusses...

Transcatheter tricuspid valve replacement: pioneering techniques and solutions for high-risk patients

18 Nov 2025 – From PCR London Valves 2025

This session explores advanced transcatheter tricuspid valve replacement techniques and outcomes. It features cases of TricValve dysfunction due to intrinsic regurgitation, pioneering 'chimney technique' implantation in complex patients, right heart remodeling post-intervention, and innovative solutions including percutaneous heterotopic bicaval valve implantation following pericardiectomy.

Transcatheter tricuspid valve replacement: pioneering techniques and solutions for high-risk patients

TAVI: complex vascular access - Part 3

18 Nov 2025 – From PCR London Valves 2025

This session focuses on managing complex vascular access challenges in TAVI procedures. It includes case discussions on non-crossable aortic valve stenosis, transseptal TAVI for severe aortic regurgitation with porcelain aorta, and percutaneous implantation in patients with unconventional anatomy or conditions like shaggy syndrome. Strategies for severe...

TAVI: alternative access - Part 2

18 Nov 2025 – From PCR London Valves 2025

This session addresses alternative access routes for TAVI in patients with challenging vascular anatomy. Topics include transapical valve-in-valve procedures complicated by severe aortic regurgitation, percutaneous TAVI via the brachiocephalic trunk, and strategies for managing hostile vascular anatomies. Solutions for scenarios where transfemoral TAVI is not feasible...

Transcatheter solutions for failed mitral TEER

18 Nov 2025 – From PCR London Valves 2025

This session presents innovative transcatheter solutions for managing failed mitral TEER procedures. It highlights advanced closure strategies for inter-clip mitral regurgitation, percutaneous approaches for recurrent mitral regurgitation, novel chordae tendineae replacement techniques, and potential bailout strategies including atrial flow regulation implantation for recurrent heart failure.

Imaging to the rescue

11 Dec 2025 – From GulfPCR-GIM 2025

This session highlighted the pivotal role of advanced intracoronary imaging techniques, particularly OCT, in complex case management such as in-stent restenosis and thrombus evaluation. Through real-world cases, it demonstrated how imaging complements physiology to guide therapeutic decisions, including the use of drug-coated balloons beyond native coronary...

Imaging to the rescue

Primary Outcomes of a Pivotal Multicenter Randomized Trial Comparing the AGENT Paclitaxel-Coated Ballon with Conventional Ballon Angioplasty for In-Stent Restenosis (AGENT IDE)

27 Oct 2023

Mirvat Alasnag provides her take on the AGENT IDE trial which was presented by Robert W. Yeh at TCT Congress 2023. This pivotal randomized trial compares the safety and efficacy of the AGENT DCB to conventional balloon angioplasty in patients with ISR. It is the first...

Dr. Mirvat Alasnag

Author

Mirvat Alasnag
Primary Outcomes of a Pivotal Multicenter Randomized Trial Comparing the AGENT Paclitaxel-Coated Ballon with Conventional Ballon Angioplasty for In-Stent Restenosis (AGENT IDE)

The greatest advance in the next 40 years would be to remove the need for angioplasty

17 May 2017

Spencer B. King performed some of the first coronary angioplasty procedures in the USA—having recently received a thank-you from the first patient that he treated. He tells The Daily Wire that the steerable guidewire, rather than the stent, was the greatest advance in angioplasty and that...

Authors :

Spencer B. King
Spencer B. King

COVID-19 vaccines: Burning questions from the community and real-world applicability

13 Jan 2021

View a number of questions of interest to the interventional cardiovascular community, as well as the real-world applicability of COVID-19 vaccine trials.

COVID-19 vaccines: Burning questions from the community and real-world applicability

The AQUATIC trial: Assessment of quitting versus using aspirin therapy in patients with stabilized coronary artery disease after stenting who require long-term oral anticoagulation

01 Sep 2025

Chiara De Biase provides her take on the results of AQUATIC presented by Martine Gilard at ESC Congress 2025 in Madrid.

Author

Chiara De Biase
The AQUATIC trial [Assessment of quitting versus using aspirin therapy in patients with stabilized coronary artery disease after stenting who require long-term oral anticoagulation: Rationale for and design of the AQUATIC double-blind randomized trial]
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