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Transcatheter solutions in young and congenital heart disease patients

17 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter solutions tailored for young and congenital heart disease patients, featuring challenging edge-to-edge repair in extracardiac Fontan physiology, systemic AV valve TEER in congenital anomalies, multidisciplinary management of repaired tetralogy of Fallot with tricuspid regurgitation, innovative TAVI in young congenital patients, and...

Pills and pumps: targeting heart failure before and after surgical and transcatheter valve interventions

18 Nov 2025 – From PCR London Valves 2025

This session examines the integrated role of heart failure therapies in the peri- and post-procedural management of patients undergoing surgical and transcatheter valve interventions. It reviews current and emerging clinical trial data, discusses identifying high-risk patients, and explores advanced modalities such as cardiac resynchronization and circulatory...

Pills and pumps: targeting heart failure before and after surgical and transcatheter valve interventions

Getting to the heart of access: mastering femoral puncture and vascular closure

18 Nov 2025 – From PCR London Valves 2025

This session provides an in-depth understanding of femoral anatomy and the critical role of imaging in ensuring safe vascular access via femoral puncture. It covers the latest equipment used for vascular access and closure, highlighting haemostasis techniques and closure devices. Interactive case scenarios offer practical insights...

Featured research - Mitral valve interventions - Part 4

18 Nov 2025 – From PCR London Valves 2025

This research-focused session presents contemporary evidence and clinical outcomes related to mitral valve interventions. It includes data on transapical mitral valve-in-ring implantation from the European Tendyne registry, prognostic utility of CT-derived fatty muscle fraction in mitral TEER, and comparative outcomes between transapical TMVR and mitral TEER....

Paravalvular leak closure - Part 3

18 Nov 2025 – From PCR London Valves 2025

This session addresses the complexities of paravalvular leak closure, emphasizing resilience in procedural approaches. It covers sizing balloon techniques that enhance treatment efficacy in aortic paravalvular leaks and explores closure strategies following Ozaki procedures. Management of mitral paravalvular leaks in high-risk patients and innovative solutions for...

TAVI complications - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session explores complex and uncommon complications associated with TAVI procedures, highlighting challenging clinical scenarios such as neurological complications in bicuspid valves, management of critically unstable left ventricles, and outcomes in complex valve interventions. Each topic offers valuable lessons for improving procedural safety and patient outcomes...

Featured research - TAVI - Part 14

18 Nov 2025 – From PCR London Valves 2025

This featured research session presents pivotal findings on transcatheter aortic valve implantation (TAVI), including 30-day and one-year outcomes from the VANTAGE trial, novel concepts for assessing aortic stenosis severity, and the influence of mitral annular calcification on conduction disturbances. Additional topics cover the role of clinical...

TAVI in challenging anatomies

18 Nov 2025 – From PCR London Valves 2025

This session focuses on the challenges of performing TAVI in complex anatomical settings. It covers issues such as valve compression, hypertrophic cardiomyopathy-related left ventricular responses, alternative management strategies during crises, and handling anatomical complexities like membranous septal aneurysm at the annulus and sinus of Valsalva in...

A randomised, multicenter, non-inferiority comparison of intravascular lithotripsy and super-high-pressure non-compliant balloons for treatment of calcified and refractory coronary lesions - The VICTORY trial

27 Oct 2025

Mirvat Alasnag provides her take on the VICTORY trial presented by Matthias Bossard at TCT 2025 in San Francisco.

Dr. Mirvat Alasnag

Author

Mirvat Alasnag
VICTORY: Intravascular lithotripsy vs. super-high-pressure PTCA in calcified and refractory coronary lesions

Impella percutaneous ventricular assist device malrotation in social media: a call to action

20 Apr 2023

The data from this study suggest that, from a SoMe perspective, correct Impella orientation is often overlooked, and that Impella malrotation is a common issue in real-world clinical practice, potentially associated with relevant complications. 

Alessandro Beneduce

Author

Alessandro Beneduce
Luca Baldetti

Author

Luca Baldetti

Author

Anna Mara Scandroglio
Mamas Mamas

Author

Mamas Mamas
Alaide Chieffo

Author

Alaide Chieffo
Impella pVAD Malrotation in social media

30 years of primary PCI – a tale of perseverance

16 May 2023

Over the last 30 years, primary PCI (pPCI) has evolved from an experimental ‘rescue’ intervention to an essential routine procedure – performed daily in cathlabs around the world – which is responsible for saving millions of lives. However, its path to success was far from smooth.

30 years of primary PCI – a tale of perseverance

BRIGHT-4 – Bivalirudin plus a high-dose infusion versus heparin monotherapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a randomised trial

07 Nov 2022

Nicola Ryan provides her take on the BRIGHT-4 study, which was presented during AHA 2022 in Chicago, & simultaneously published in the Lancet.

This study was a randomised control trial designed to assess if bivalirudin plus a high dose infusion for 2-4 hours post PPCI was superior to unfractionated...

Nicola Ryan

Author

Nicola Ryan
BRIGHT-4 – Bivalirudin plus a high-dose infusion versus heparin monotherapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a randomised trial

Ivus or angiography guidance for PCI in complex coronary bifurcation lesions (DKCRUSH-VIII)

31 Mar 2026

Nicola Ryan provides her take on DKCRUSH-VIII, a randomised controlled trial comparing IVUS versus angiography guidance for PCI, predominantly using the DKCRUSH technique in patients with complex bifurcation lesions, as presented by Shaoliang Chen at ACC.26 in New Orleans.

Nicola Ryan

Author

Nicola Ryan
DKCrush VIII: Ivus or angiography guidance for PCI in complex coronary bifurcation lesions

Intravascular ultrasound-guided versus angiography-guided percutaneous coronary intervention in acute coronary syndromes: The multicenter, randomized, blinded, IVUS-ACS Trial

09 Apr 2024

Marco Spagnolo and Daniele Giacoppo report the main results of the IVUS-ACS trial presented by Shao-Liang Chen, from the Nanjing First Hospital, Nanjing Medical University, Nanjing, in a Featured Clinical Research session at ACC.24 in Atlanta and simultaneously published in The Lancet.(1)

Daniele Giacoppo

Author

Daniele Giacoppo
Marco Spagnolo

Author

Marco Spagnolo
IVUS-guided vs angiography-guided PCI in acute coronary syndromes
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