08 Nov 2025
The importance of PPM in younger patients in TAVI valve choice
Sponsored by Medtronic
Summary
Kristoffer Russell discusses prosthesis–patient mismatch (PPM), which can increase mortality, heart failure hospitalisations, and reduce functional recovery, especially in younger patients. While less common after TAVI than surgical valve replacement, studies show up to 30% of younger, low-risk TAVI patients still experience moderate or severe PPM, which negatively affects long-term outcomes. Dr Russell emphasises careful pre-procedural planning, optimal valve expansion, and consideration of valve type to minimise PPM and improve outcomes, particularly in patients with longer life expectancy.