Georg Nickenig
Latest contributions
Cardiovalve hits the TARGET: advancing transcatheter valve replacement
18 Nov 2025 – From PCR London Valves 2025
This session highlights the features and procedural steps of the next-generation Cardiovalve systems for tricuspid and mitral valve replacement. It reviews interim results from the TARGET study, emphasizing echocardiographic findings and reverse remodeling effects, and discusses best practices for patient selection and the learning pathway to...
Spotlight on a selection of top Late-breaking Trials presented at PCR London Valves 2025
17 Nov 2025
View a snapshot of the results of these 4 trials in valvular and structural interventions presented in London during this year's Heart Team Course!
Featured research - Mitral valve interventions: Physiology & device innovation
17 Nov 2025 – From PCR London Valves 2025
This session highlights groundbreaking research on mitral valve interventions featuring advanced transcatheter techniques. Topics include coronary physiology assessment with vFFR in severe mitral regurgitation, predictive versus actual outcomes in TMVR, innovative devices like Epygon and INNOVALVE, and novel approaches such as the ReNiva posterior leaflet replacement...
Hot topics in structural heart: addressing patients' unmet needs with EVOQUE TTVR and SAPIEN THV-in-THV
17 Nov 2025 – From PCR London Valves 2025
This session addresses emerging topics in structural heart disease by examining patient-centered solutions such as EVOQUE transcatheter tricuspid valve replacement (TTVR) and SAPIEN transcatheter heart valve-in-heart valve (THV-in-THV) procedures. It covers the latest data from Europe on redo TAVI, lifetime management strategies beginning with initial prosthesis...
TARGET study interim results: safety and performance of Cardiovalve replacement system for tricuspid regurgitation
16 Nov 2025 – From PCR London Valves 2025
Georg Nickenig and Christopher Allen discuss transcatheter replacement for the tricuspid valve and a dedicated transfemoral device in this interview, focusing on the TARGET study.
TARGET set out to answer two questions: can tricuspid regurgitation (TR) be reduced to mild or zero, and what are the safety...
Emergency transcatheter valve interventions: alternative therapy or bridge to surgery?
16 Nov 2025 – From PCR London Valves 2025
This session offers a compelling case-based exploration of emergency transcatheter valve interventions, demonstrating their potential as life-saving alternatives or bridges to surgery in high-risk patients. Through detailed clinical scenarios including cardiogenic shock, acute papillary muscle rupture, and severe aortic regurgitation from infective endocarditis, participants gain practical...
Mitral TEER - LIVE case
16 Nov 2025 – From PCR London Valves 2025
This live educational case from Hospital Álvaro Cunqueiro in Vigo, Spain, offers an in-depth look at Mitral TEER, including patient presentation, imaging analysis, operator strategy, and device overview. The session also features a recorded case from the Heart and Diabetes Center NRW in Germany, providing comprehensive...
Late-Breaking Trials in transcatheter mitral, tricuspid and aortic interventions - Part 1
16 Nov 2025 – From PCR London Valves 2025
This session presents pivotal late-breaking trials in transcatheter mitral and aortic valve interventions. Explore one-year outcomes from the AltaValve early feasibility study featuring atrial fixation TMVR, interim results from the TARGET study assessing Cardiovalve for tricuspid regurgitation, five-year data on transapical TMVR, and outcomes of TAVI...
Updates in tricuspid interventions: from the procedure to follow-up
15 Apr 2025
Watch the replay of this webinar with G. Nickenig, J. Dreyfus, S. Kar and P. Lurz and learn about the follow-up results of the TRILUMINATE trial, and so much more!
Recurrent and residual tricuspid regurgitation after transcatheter repair - Assessment and management
26 Nov 2024 – From PCR London Valves 2024
Join us as we delve into the critical topic of recurrent and residual tricuspid regurgitation after transcatheter repair. Gain valuable insights on how to avoid these complications, learn to assess the underlying mechanisms and severity, and explore the latest options for interventional treatment. This session, developed...
Transcatheter mitral intervention for failed surgical valves and rings - The toolkit
26 Nov 2024 – From PCR London Valves 2024
Looking to enhance your approach to failed surgical mitral valves and rings? This video is a must-watch!
You’ll explore patient selection, master the steps of mitral valve-in-valve and valve-in-ring procedures, and learn strategies like valve cracking and LAMPOON to overcome key challenges.
Advanced imaging in tricuspid TEER - LIVE case
26 Nov 2024 – From PCR London Valves 2024
Watch a LIVE case followed by a recorded case on how to use imaging in tricuspid TEER:
- A 64-year-old male with a history of CABG and COPD, ICD implantation (2013) mitraclip (2018) and poor LV function (25%), presented a torrential functional tricuspid regurgitation. The operators implanted 2...
RESHAPING the transcatheter treatment of mitral and tricuspid regurgitation
25 Nov 2024 – From PCR London Valves 2024
Join this compelling session focused on the transcatheter treatment of mitral and tricuspid regurgitation. Explore detailed case discussions, including a mitral regurgitation case, a challenging MitraClip procedure, and a severe tricuspid regurgitation case. Discover key takeaways from the RESHAPE, MATTERHORN, and Tri.FR trials, and learn how...
Advanced mitral TEER - LIVE case
Recommended by PCR
24 Nov 2024 – From PCR London Valves 2024
Join us for a LIVE case followed by a recorded case highlighting advanced treatments for severe secondary mitral regurgitation:
- A 75-year-old man with permanent AF, a history of CABG, and symptomatic severe secondary MR (atrial and ischemic causes) with low LV function (45%) underwent mitral repair with...
Innovation never stops: Cardiovalve in action!
24 Nov 2024 – From PCR London Valves 2024
Join us as we explore the latest advancements in transcatheter tricuspid valve replacement technologies. This session develops the anatomical and imaging challenges associated with this rapidly developing clinical field and provides an update on the Cardiovalve tricuspid clinical program, illustrated by a recorded case.
PCR Tricuspid Focus Group - referral meeting in Bonn
13 Jun 2024
Join your peers for this meeting on 24 January 2025 in Bonn, Germany!
To repair or to replace the mitral valve: that is the question
16 May 2024 – From EuroPCR 2024
This session provides a comprehensive understanding of both transcatheter edge-to-edge repair (TEER) and transcatheter mitral valve replacement (TMVR) techniques, including their respective advantages, suitability criteria, and clinical outcomes. The session features insights from a surgeon's perspective on the considerations and techniques involved in mitral valve repair...
Clinical outcomes of transcatheter mitral and tricuspid valve repair and replacement
15 May 2024 – From EuroPCR 2024
TAVI updates: expanding indications
14 May 2024 – From EuroPCR 2024
This session presents the latest updates and evidence on the expanding indications for transcatheter aortic valve implantation (TAVI). It covers topics such as the impact of unfavorable aortic valve anatomy on TAVI outcomes, sex-specific differences in cardiac damage in aortic stenosis patients undergoing TAVI, the use...
Transcatheter tricuspid valve intervention - Too many patients, too little evidence
21 Nov 2023 – From PCR London Valves 2023
Watch this tricuspid valve session to explore the evolution of transcatheter tricuspid intervention, from a once deemed crazy concept to an everyday procedure. Reflect on the choice between replacement and repair for the tricuspid valve and understand the necessity of a multidisciplinary approach, uniting specialists in...
Tricuspid transcatheter valve replacement: Cardiovalve keeps things in motion
20 Nov 2023 – From PCR London Valves 2023
Participate in this session to stay informed about the latest advancements in TTVR, receive updates on the Cardiovalve tricuspid program, and gain insights into how imaging demonstrates the concept underlying Cardiovalve transcatheter valve replacement technology.
New devices for tricuspid valve intervention
20 Nov 2023 – From PCR London Valves 2023
Join this session for a quick overview of groundbreaking devices shaping tricuspid valve interventions: witness the first-in-man experience with a cross-caval device designed for the treatment of tricuspid regurgitation, navigate through a challenging case involving a patient with massive tricuspid regurgitation and a permanent pacemaker lead and...
Controversies in atrioventricular valves - The Heart Team ring, Vol II
19 Nov 2023 – From PCR London Valves 2023
This session offers an opportunity to engage in a real case discussion led by an advanced Heart Team. Participate in discussions on controversial decision-making scenarios and stay informed about the latest clinical evidence related to MitraClip, Tendyne, and TriClip therapies.
The Top Late-Breaking Trials: TRISCEND II, TRILUMINATE at 3 years, EuroSMR score, CLASP IID, OPERA-TAVI...
19 Nov 2023 – From PCR London Valves 2023
Discover the top late-breaking trials which were presented during PCR London Valves 2023:
- TRISCEND II: A randomised trial of transcatheter tricuspid valve replacement vs medical therapy
- Percutaneous edge-to-edge repair for tricuspid regurgitation: TRILUMINATE trial three-year outcomes
- Transcatheter mitral valve-in-valve vs. redo surgical replacement for degenerated bioprostheses
- Artificial intelligence derived risk...
Knocking mitral regurgitation down to improve outcomes: earlier is better, but better late than never! (Episode 2: the left side)
18 May 2023 – From EuroPCR 2023
Help optimize your patients' prognosis by attending this session! You'll learn how proper patient selection and timely interventions lead to lasting results and how to use the latest real-world registry data to gain insight into the safety and effectiveness of M TEER.
Valvular heart disease: novel transcatheter approaches
18 May 2023 – From EuroPCR 2023
Explore this thrilling session on transcatheter approaches for valvular heart disease, featuring the latest advancements, emerging techniques, and revolutionary research. Join your peer as they present novel strategies and devices aimed at improving valvular disease management.
Management of tricuspid valve regurgitation
11 Dec 2022
Watch the replay of the 2nd webinar on Tricuspid valve disease: patient pathways. You’ll learn all about 'Management of tricuspid valve regurgitation'
Transcatheter tricuspid valve intervention is booming: where are we now? and where are we going?
29 Nov 2022 – From PCR London Valves 2022
Watch these presentations to better understand what's happening in the field of tricuspid valve intervention and to appreciate the characteristics of current and newly emerging transcatheter devices.
A case-based tailored approach to the treatment of mitral valve disease: the Heart Team ring
28 Nov 2022 – From PCR London Valves 2022
Join an advanced Heart Team in a real case discussion to understand what "mitral valve complexity" really means and to learn how to optimise selection between repair and replacement options.
How to deal with residual or recurrent mitral regurgitation after failed surgical or transcatheter repair
28 Nov 2022 – From PCR London Valves 2022
Consul this session to learn more about the available treatment options after failed mitral surgical or transcatheter procedures, the factors that increase the likelihood of residual/recurrent mitral regurgitation, and more!
