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Bifurcation lesions

Find all the latest content on bifurcation lesions published on this website.

The percutaneous treatment of coronary bifurcation lesions is very dynamic with an ongoing evolution in clinical approaches and techniques and the management of more complex cases continuing to evolve. Keep up-to-date about all these changes along with the latest research and devices as well as advances in imaging, the use of adjunctive pharmacotherapy, vascular access or understanding bleeding risks. Use the filters below to access PCRonline resources.

Keep on Learning! Benefit from PCR’s wide choice of education continuum on bifurcation lesions: Courses, educative tools and much else besides.

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Bifurcation lesion

264 results

Comparison of drug-coated versus conventional balloons for treatment of side branches of bifurcation lesions: the OCVC-BIF study

29 Oct 2025

Ali Nazmi Calik provides his take on the OCVC-BIF study presented by Takayuki Ishihara at TCT 2025, in San Francisco.

Author

Ali Nazmi Calik
Comparison of drug-coated versus conventional balloons for treatment of side branches of bifurcation lesions: The OCVC-BIF study

PCR @ TCT 2025 - Get the international perspective!

15 Oct 2025

Thanks to the contribution of a team of interventional cardiologists from around the globe, get the international perspective on Late-breaking Clinical Trials and Science released at TCT 2025 - check out the list below.

PCRonline @ TCT 2025 - get the international perspective!

Calcium nodule in circumflex ostium: a complex problem

31 Oct 2025

Analyse this case of an 83-year-old male patient, hypertensive, ex-smoker, with severe COPD and peripheral arterial disease with unstable angina. Coronary angiography revealed a severely calcified lesion in a complex anatomical area, making revascularisation a therapeutic challenge.

Jorge Perea

Author

Jorge Perea
Javier Suarez de Lezo

Author

Javier Suarez de Lezo
Soledad Ojeda

Author

Soledad Ojeda
Prof. Manuel Pan

Author

Manuel Pan
Calcium nodule in circumflex ostium: a complex problem

Coronary bifurcation lesions

08 Jul 2025

This updated chapter by T. Lefèvre provides a practical guide on strategies currently implemented in the treatment of coronary bifurcations, and highlights the main challenges and most debated issues to propose recommendations for an optimal approach. 

Authors :

Lefèvre T., Hovasse T.
The PCR Textbook chapter on Bifurcation lesions

PCI for complex bifurcation disease - LIVE Case

23 May 2025 – From EuroPCR 2025

A 60-year-old male patient presented with an inferior STEMI one month ago, which was treated with RCA and LCx PCI. He was referred for LAD/diagonal PCI. The LV function was reduced (EF 45 %). The team performed a DK crush PCI, guided by IVUS.

LIVE Educational Case...

PCI for complex bifurcation disease - LIVE Case

Complex multivessel disease - LIVE Case

21 May 2025 – From EuroPCR 2025

An 89-year-old male patient presented with stable angina, preserved LV function and some risk factors such as hypertension and diabetes. CT scan and angiography revealed occlusion of proximal RCA and bifurcation lesions on LAD and circumflex (medina 1,1,1). Operators treated the bifurcation lesions with provisional stenting.
Regarding...

Complex multivessel disease - LIVE Case

What are the essentials of the provisional strategy for non-left main true bifurcation lesions?

21 May 2025 – From EuroPCR 2025

Giuseppe Di Gioia and Jens Flensted Lassen explore the essentials of the provisional stenting strategy for non-left main true bifurcation lesions. This stepwise approach offers simplicity while preserving flexibility: start with one stent in the main vessel, and keep the option open for a second if...

What are the essentials of the provisional strategy for non-left main true bifurcation lesions?

What are the fundamentals of an upfront two-stent strategy for bifurcation PCI?

21 May 2025 – From EuroPCR 2025

Nicola Ryan explores the fundamentals of an upfront two-stent strategy in bifurcation PCI with Dejan Milasinovic. When the side branch shows significant, high-grade stenosis or extensive disease, direct treatment - via POBA, DCB, or a second stent - may be preferred. Anatomy guides the decision between...

What are the fundamentals of an upfront two-stent strategy for bifurcation PCI?

How to successfully approach calcified bifurcation lesions?

20 May 2025 – From EuroPCR 2025

Calcified bifurcation lesions remain one of the toughest challenges in interventional cardiology, combining two high-risk features into one complex scenario.

In this discussion, Dejan Milasinovic, Miroslaw Ferenc, and Mohamed Abdel Wahab explain why this subset deserves dedicated attention. They highlight the critical role of intra-coronary imaging to...

How to successfully approach calcified bifurcation lesions?

Comparison of stent geometry achieved by different side-branch ballooning techniques for bifurcation provisional stenting: the CRABBIS Trial

31 Mar 2025

Which ballooning technique is best after main vessel stenting in bifurcation PCI? This two-part study compares two key approaches: PKP (POT, kissing balloon inflation, final POT) and PSP (POT, isolated side branch dilation, final POT) to determine the optimal strategy.

Reviewer

Ali Nazmi Calik

Reviewer

Aaysha Cader
Comparison of stent geometry achieved by different side-branch ballooning techniques for bifurcation provisional stenting: the CRABBIS Trial